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Clin. biomed. res ; 39(1): 1-8, 2019.
Article in Portuguese | LILACS | ID: biblio-1025955

ABSTRACT

Introdução: Exames diagnósticos contrastados oferecem riscos para o desenvolvimento de Insuficiência Renal Aguda pós-contraste (IRA-PC), principalmente em pacientes com doença renal prévia. O objetivo deste estudo foi verificar se a função renal foi avaliada antes e após a realização de exame contrastado. Métodos: Coorte retrospectiva com 2778 pacientes que realizaram tomografia computadorizada (TC) contrastada em que foi verificada a creatinina sérica (CrS) pré e pós-exame, presença de fatores de risco, incidência de IRA-PC e óbito até 10 meses pós-TC. Resultados: Somente 263 (9,5%) apresentaram avaliação da função renal pré e pós-exame dentro dos prazos estabelecidos (7 dias para pacientes internados e 180 dias para ambulatoriais pré-exame, e 48 a 72 horas pós-exame), sendo que 91,6% eram de pacientes internados. IRA-PC foi observada em 38 (14,4%) pacientes e foi associada ao uso de medicamentos nefrotóxicos (Odds Ratio 1,645; IC95%: 1,138­2,390) e maior risco de óbito pós-exame (Razão de Incidência 1,84; IC95%:1,17-2,83). Conclusão: A grande maioria dos pacientes não apresentava adequada avaliação da função renal pré e pós-TC, principalmente em nível ambulatorial. Sugere-se o estabelecimento de medidas educativas para promover a aderência do corpo clínico à avaliação da função renal para pacientes de risco para IRA-PC. (AU)


Introduction: Contrast-enhanced diagnostic tests involve risks for the development of post-contrast acute kidney injury (PC-AKI), especially in patients with previous renal disease. The aim of this study was to investigate whether renal function was evaluated before and after the contrast-enhanced test. Methods: In this retrospective cohort of 2778 patients who underwent contrast-enhanced computed tomography (CT), pre- and post-CT serum creatinine (SCr), presence of risk factors, incidence of PC-AKI, and death within 10 months post-CT were investigated. Results: Only 263 (9.5%) patients had pre- and post-CT renal function evaluation performed within the established time frames (7 days for inpatients and 180 days for outpatients pre-CT and 48 to 72 hours post-CT), with 91.6% being inpatients. PC-AKI was observed in 38 (14.4%) patients and was associated with use of nephrotoxic drugs (odds ratio: 1.645, 95% CI: 1.138-2.390) and higher risk of death post-CT (incidence ratio: 1.84; 95% CI: 1.17-2.83). Conclusion: The vast majority of patients did not undergo an adequate pre- and post-CT renal function evaluation, especially at the outpatient level. Educational measures should be developed to promote adherence of clinical staff to renal function evaluation for patients at risk for PC-AKI. (AU)


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Tomography, X-Ray Computed/adverse effects , Acute Kidney Injury/chemically induced , Tomography, X-Ray Computed/mortality , Risk Factors , Acute Kidney Injury/epidemiology
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