The subcutaneous capsules for foreign body in fetal rabbits: preliminary report

In terms of wound healing, there are fundamental intrinsic and extrinsic differences between fetuses (scar-free healing) and adults. The fetus exhibits less typical inflammatory response (signifiquently neutropenic) with an underdeveloped self-nonself immunologic identity and a lack of cellular immunity. The recruitment of inflammatory cells to a wound may play an important role in the resulting cellular processes and ultimately affect the quality of the healing response. Foreign bodies can act as a source of infection and immunologic reactions. In contrast, there have been few studies of the wound healing of fetus with foreign bodies, where in adults, wounds are healed by tissue regeneration rather than capsule formation and a foreign body reaction. In this study, the wound healing process in an adult rabbit and fetus group, in which either silicone or a sponge was inserted in the uterus, were compared. All specimens showed capsule formation with fibroblast, collagen deposition, neovascularization, and infiltration of inflammatory cells. However, the fetal specimen exhibited mainly acute inflammatory responses and the capsule contained less fibroblasts and collagen deposition. In addition, myofibroblast expression, which mediates wound contracture, was lower in the fetal specimen. These findings were common with cotton implants, which were expected to induce a severe inflammatory response. The inflammatory response induced by foreign materials in fetal tissue showed similar response with that of incisional wound healing. This study may provide a basis for the use of implants such as silicone in future fetal surgery.

Utero septado con duplicación cervical y tabique vaginal: una malformación rara / Septate uterus with cervical duplication. A rare malformation

Se presentan dos casos de una malformación mulleriana que incluye útero septado con duplicación cervical y tabique vaginal longitudinal total. Existen pocos casos informados previamente en la literatura médica. Se realiza la discución y una revisión de la literatura

Utero didelfo, imperfuracao vaginal unilateral e agenesia renal ipsilateral: descricao de um caso / Uterus didelphys, unilateral imperfurated vagina and ipsilateral renal agenesis: a case report

A combinacao do utero didelfo com imperfuracao vaginal unilateral e agenesia renal ipsilateral e rara e, em geral, e encontrada em mulheres com ciclos menstruais normais. Nestes casos, devido ao acumulo de sangue menstrual na hemivagina obstruida, as pacientes podem apresentar massa pelvica e dismenorreia severa. Neste artigo e descrito um caso de uma paciente de 14 anos, a qual apresentava dor pelvica ha 6 meses. Os autores revisam tambem a embriologia, diagnostico e manejo desta rara associacao

Sistemas moleculares en la interacciones celulares: II. Iimplantación embrionaria en mamíferos / Molecular systems in the cellular interactions: II. Embrionary implantation in mammals

En el presente trabajo se revisan los sistemas moleculares de reconocimiento y adhesión celulares que participan en la implantación embrionaria de los mamíferos.En el proceso de implantación embrionaria, las interacciones son compejas, ya que son diversos tipos celulares los involucrados: las células del trofoblasto del embrión interactúan con varias células uterinas y con sus respectivas matrices extracelulare; participando lactosaminoglicanos, integrinas, cadherinas y galactosil transferasas.

Flujo genital y embarazo / Genital exuaste and pregnancy

Se trata de un estudio prospectivo sobre flujo genital en 73 pacientes gestantes, en las que se practicò examen en fresco del flujo que luego se tratò con agentes tòpicos, estableciendose la utilidad d la terapèutica mediante examen en fresco posterior. Se propone como una alternativa para el tratamiento de las colpitis en las pacientes de bajos recursos econòmicos, asi como para su empleo en areas perifèricas y rurales