Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 1.085
Filter
1.
Rev. bras. med. esporte ; 29: e2022_0168, 2023. tab, graf
Article in English | LILACS | ID: biblio-1394832

ABSTRACT

ABSTRACT Introduction: Several programs to encourage physical activity has been encouraged to reduce the sedentary lifestyle in China. Running is among them because it has potentially positive effects on cardiovascular diseases, hypertension, diabetes mellitus, and hypercholesterolemia, in addition to the intrinsic psychological and social benefits of outdoor sports. Objective: Explore the protective effect of running on the cardiac system by analyzing strategies for cultivating exercise health awareness. Methods: A group of ten healthy volunteers, five women aged 25-35 years, underwent a 45-minute running program, performed four times a week for three weeks. Data collected by spirometry and cardiac monitoring were collected, treated, compared, and discussed. This paper introduced the concept of subjective exercise intensity to find the best analysis and judgment of Cardiac Function. Finally, a quantitative investigation involving the analysis of 315 questionnaires explored the current status of sports health awareness in running fans. Results: Heart rate amplitude during running remained in the range of 120-160, belonging to the normal heart rate range for the surveyed audience. In most cases, women's heart rate was higher than men's (P<0.05). The exercise intensity was fixed at a frequency below the value of 16, which is a slightly strenuous stage, and the relative exercise intensity was controlled between 50% and 71.5%. Conclusion: Running has a good cardiac protective effect, and its followers are highly aware of sports health. Due to the beneficial effect of sports practice, its dissemination is recommended as a form of physical and social therapeutic activity. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.


RESUMO Introdução: Com o intuito de reduzir o índice de sedentarismo na China, diversos programas de incentivo à atividade física foram estimulados. A corrida está dentre eles pois tem potenciais efeitos positivos nas doenças cardiovasculares, hipertensão arterial, diabetes mellitus e hipercolesterolemia, além dos benefícios psicológicos e sociais intrínsecos na prática esportiva ao ar livre. Objetivo: Explorar o efeito protetor da corrida no sistema cardíaco analisando as estratégias para a cultura da consciência sanitária do exercício. Métodos: Um grupo de dez voluntários saudáveis, com cinco mulheres e idade entre 25 a 35 anos foram submetidos a um programa de corrida por 45 minutos, realizado quatro vezes por semana, durante três semanas. Dados coletados por espirometria e monitoramento cardíaco foram coletados, tratados, comparados e discutidos. Este artigo introduziu o conceito de intensidade de exercício subjetivo para encontrar a melhor análise e julgamento da Função Cardíaca. Por fim, uma investigação quantitativa envolvendo a análise de 315 questionários explorou a situação atual da conscientização em saúde esportiva em adeptos da corrida. Resultados: A amplitude de frequência cardíaca durante a corrida manteve-se na faixa de 120-160, pertencente à faixa normal de frequência cardíaca ao público pesquisado. A frequência cardíaca das mulheres foi maior do que a dos homens na maioria dos casos (P<0,05). A intensidade do exercício fixou-se numa frequência inferior ao valor de 16, que é um estágio ligeiramente extenuante, e a intensidade relativa do exercício ficou controlada entre 50% e 71,5%. Conclusão: A corrida apresenta um bom efeito protetor cardíaco, seus adeptos possuem elevada conscientização da saúde esportiva. Devido ao efeito salutar da prática esportiva, recomenda-se a sua divulgação como forma de atividade terapêutica física e social. Nível de evidência II; Estudos terapêuticos - investigação dos resultados do tratamento.


RESUMEN Introducción: Con el fin de reducir el estilo de vida sedentario en China, se han estimulado varios programas para fomentar la actividad física. La carrera se encuentra entre ellos porque tiene potenciales efectos positivos sobre las enfermedades cardiovasculares, la hipertensión, la diabetes mellitus y la hipercolesterolemia, además de los beneficios psicológicos y sociales intrínsecos del deporte al aire libre. Objetivo: Explorar el efecto protector de correr sobre el sistema cardíaco analizando las estrategias para cultivar la conciencia de la salud del ejercicio. Métodos: Un grupo de diez voluntarios sanos, cinco mujeres, con edades comprendidas entre los 25 y los 35 años, fueron sometidos a un programa de carrera durante 45 minutos, realizado cuatro veces por semana durante tres semanas. Los datos recogidos por la espirometría y la monitorización cardíaca fueron recogidos, tratados, comparados y discutidos. Este trabajo introdujo el concepto de intensidad subjetiva del ejercicio para encontrar el mejor análisis y juicio de la Función Cardíaca. Por último, una investigación cuantitativa que incluyó el análisis de 315 cuestionarios exploró el estado actual de la conciencia de la salud deportiva en los aficionados a las carreras. Resultados: La amplitud de la frecuencia cardíaca durante la carrera se mantuvo en el rango de 120-160, perteneciendo al rango de frecuencia cardíaca normal para el público encuestado. La frecuencia cardíaca de las mujeres fue mayor que la de los hombres en la mayoría de los casos (P<0,05). La intensidad del ejercicio se fijó en una frecuencia inferior al valor de 16, que es una etapa ligeramente agotadora, y la intensidad relativa del ejercicio se controló entre el 50% y el 71,5%. Conclusión: La acción de correr presenta un buen efecto cardioprotector, sus adeptos poseen alta conciencia de la salud deportiva. Debido al efecto saludable de la práctica deportiva, se recomienda su difusión como forma de actividad terapéutica física y social. Nivel de evidencia II; Estudios terapéuticos - investigación de los resultados del tratamiento.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Young Adult , Cardiovascular Diseases/prevention & control , Exercise/physiology , Diabetes Mellitus/prevention & control , Heart Rate/physiology , Hypercholesterolemia/prevention & control
3.
Rev. ADM ; 79(4): 213-217, jul.-ago. 2022.
Article in Spanish | LILACS | ID: biblio-1395859

ABSTRACT

La cardiopatía isquémica es un padecimiento que se caracteriza por la falta de oxígeno del músculo cardiaco y es la principal causa de infarto de miocardio. Existen múltiples factores que predisponen al desarrollo de ésta como la obesidad, la hiperlipidemia, el sedenta- rismo, tabaquismo, diabetes e hipertensión. Dadas las características que configuran la fisiopatología de la cardiopatía isquémica, existen diversas consideraciones que deben ser tomadas en cuenta toda vez que el estomatólogo brinde atención a un paciente con este padecimiento. El objetivo del presente artículo es conocer todo lo relacionado con la fisiopatología de la cardiopatía isquémica, sus manifestaciones clínicas, su tratamiento médico y lo más importante, las consideraciones que deben tomarse en el consultorio dental cuando se atienda a un paciente que padezca esta condición (AU)


Ischemic heart disease is a condition characterized by a lack of oxygen in the heart muscle and is the main cause of myocardial infarction. There are multiple factors that predispose to the development of this, such as obesity, hiyperlipidemia, sedentary lifestyle, smoking, diabetes and hypertension. Given the characteristics that make up the pathophysiology of ischemic heart disease, there are various considerations that must be taken into account whenever the stomatologist provides care to a patient with this condition. The objective of this article is to know everything related to the pathophysiology of ischemic heart disease, its clinical manifestation, its medical treatment and most importantly, the considerations that must be taken in the dental office when caring for a patient with this condition (AU)


Subject(s)
Humans , Myocardial Ischemia/etiology , Myocardial Ischemia/drug therapy , Dental Care for Chronically Ill/methods , Myocardial Infarction/complications , Cardiovascular Diseases/prevention & control , Risk Factors , Myocardial Ischemia/epidemiology , Adrenergic beta-Antagonists/therapeutic use , Sedentary Behavior , Fibrinolytic Agents/therapeutic use , Nitrates/therapeutic use
4.
Int. j. cardiovasc. sci. (Impr.) ; 35(3): 304-315, May-June 2022. tab, graf
Article in English | LILACS | ID: biblio-1375639

ABSTRACT

Abstract Background Obesity and overweight in childhood can increase the risk of developing cardiovascular disease throughout live. Objectives This study provides an update of a meta-analysis of randomized clinical trials (RCT) published in 2014, to assess the effects of physical activity interventions on preventing cardiovascular risk factors in childhood. Methods This update combines data from the previous search with new data obtained from June 2013 to June 2020. Searches were performed on PubMed, EMBASE and Cochrane CENTRAL. The RCTs enrolled used interventions with physical activity longer than six months in school children aged 6-12 years, and evaluated body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol (TC), triglyceride (TG), and low-density lipoprotein (LDL) and high-density lipoprotein (HDL) levels. Data analysis was performed using a random-effects model and a P value <0.05 was considered statistically significant. Results A total of 28,603 articles were retrieved, and 17 RCTs (11,952 subjects) were included. Physical activity interventions were associated with reduction in SBP [−2.11mmHg (95%CI −3.67, −0.54), I243%], DBP [−2.08mmHg (95%CI −3.68, −0,49), I265%] and TG [-0.08mmol/L (95% CI -0.13, -0.03), I20%], and increase in TC [0.17mmol/L (95%CI 0.04, 0.30), I20%]. However, the interventions were not associated with reductions in BMI [−0.03 kg/m2 (95%CI −0.17, 0.10), I20%]. Conclusion This update confirms and reinforces the beneficial effects of physical activity intervention in reducing systolic and diastolic blood pressure and TG levels.


Subject(s)
Humans , Male , Female , Child , Cardiovascular Diseases/prevention & control , Exercise , Heart Disease Risk Factors , Sports , Students , Exercise Test , Pediatric Obesity , Physical Conditioning, Human
6.
Int. j. cardiovasc. sci. (Impr.) ; 35(3): 400-409, May-June 2022. tab, graf
Article in English | LILACS | ID: biblio-1375644

ABSTRACT

Abstract Background: Due to the growing concern about work-related social and health aspects, occupational health and safety has become relevant. Objective: This work aims to develop a model to assist cardiovascular risk management in a team of haul truck operators, who work in rotating shifts at a mining company in Brazil. Methods: This longitudinal study evaluated risk factors for cardiovascular diseases of 191 mineworkers at three times points - 2010, 2012, and 2015. In addition, the risk of developing cardiovascular diseases was calculated, and the risk factors were analyzed using the chi-square test, the U Mann-Whitney test, and binary logistic regression. The significance level was set at 5%. Results: In the study period, body weight, body mass index (BMI), waist-to-height ratio (WHR), systolic (SBP), and diastolic blood pressure (DBP), total cholesterol, high-density lipoprotein cholesterol (HDL-C), and triglycerides levels of the study group increased. In 2015, there was a high prevalence of alcohol intake, overweight or obesity, central obesity, inadequate WHR, high blood pressure, total cholesterol above 190 mg/dL, and triglycerides above 150 mg/dL. An association was identified between increased cardiovascular risk and age, SBP, HDL-C, low-density lipoprotein cholesterol (LDL-C), and elevated glucose levels. Conclusion: Intense interventions for reduction and prevention of elevated alcohol intake, blood pressure levels, WHR, metabolic syndrome, blood glucose, and LDL-C levels, and low HDL-C levels are needed. In addition, a close monitoring of mine workers over 38 years of age who smoke, consume alcoholic beverages, and have altered blood glucose levels is important.


Subject(s)
Humans , Male , Female , Occupational Health , Miners , Heart Disease Risk Factors , Tobacco Use Disorder , Alcohol Drinking , Cardiovascular Diseases/prevention & control , Longitudinal Studies , Metabolic Syndrome , Metabolic Syndrome/complications , Shift Work Schedule , Hypercholesterolemia
7.
Rev. urug. cardiol ; 37(1): e201, jun. 2022. tab, graf
Article in Spanish | LILACS, BNUY, UY-BNMED | ID: biblio-1390034

ABSTRACT

Antecedentes: aunque la enfermedad cardiovascular (ECV) es la principal causa de muerte de las mujeres en Uruguay, ellas no lo perciben. Objetivos: el propósito de este estudio fue evaluar la percepción, el conocimiento y las conductas de prevención de las ECV entre mujeres por grupos de edad, nivel socioeconómico (NSE) y región, así como su conocimiento sobre factores de riesgo, síntomas y comportamientos cardiosaludables. Métodos: en 2020 se encuestaron vía web 700 mujeres de entre 20 y 70 años, residentes en Uruguay (Montevideo: 301, interior del país: 399). Se pautó publicidad en redes sociales para convocar a la población objetivo a participar. Las integrantes de la muestra, que completaron una encuesta autoadministrada, presentaban distribución similar a la población general en cuanto al NSE y la edad. Resultados: las mujeres encuestadas percibieron a la ECV como principal problema de salud (PS) en el 10% y como primera CM en el 18%. Las montevideanas, comparadas con las del interior, tuvieron mayores niveles de percepción (PS: 13% vs. 7%-CM: 20% vs. 17%); así como las de NSE alto vs. las de medio-bajo (PS: 17% vs. 8%-CM: 29% vs. 14%). La percepción y el conocimiento sobre ECV son bajos, las jóvenes son las menos informadas (escasos/muy escasos: 62%). Los médicos advierten poco sobre síntomas (23%) y estrategias de prevención (48%). Conclusión: la percepción de las mujeres encuestadas sobre la ECV es baja, existiendo brechas por edad, NSE y región. En la consulta, los médicos informan poco sobre el tema. Es necesario un esfuerzo continuo para mejorar la percepción de las mujeres sobre la ECV en su propio género, intentando llegar principalmente a las poblaciones de mayor riesgo.


Background: although cardiovascular disease (CVD) is the main cause of death for women in Uruguay, they do not perceive it. Objectives: the purpose of this study was to evaluate the perception, knowledge, and prevention behaviors of CVD among women by age group, socioeconomic level (SEL), and region, as well as knowledge of risk factors, symptoms, and heart-healthy behaviors. Method and result: online survey of 700 women residents of Uruguay (Montevideo: 301, interior of the country: 399), was conducted in 2020, ages between 20 and 70 years. Advertising was scheduled on social networks, calling the target population to participate in that research by completing a selfadministered survey, obtaining a set of cases with a similar distribution to the general population in terms of SEL and age. CVD was perceived in 10% as the main health problem (HP) and 18% as the first CD. Women from Montevideo vs. interior had higher levels of perception (HP: 13% vs. 7%-CD: 20% vs. 17%); as well as those of high vs. those of mediumlow SEL (HP: 17% vs. 8%-CD: 29% vs. 14%). The perception and knowledge about CVD are low, with young women being the least informed (little/very little: 62%). Doctors report little on symptoms (23%) and prevention (48%). Conclusion: the perception of the women surveyed about CVD is low, with gaps by age, NSE and region. Doctors inform little about this topic during clinical visits. A continuous effort is necessary to improve women's perception of CVD in their own gender, trying to reach mainly the populations at greatest risk.


Antecedentes: embora a doença cardiovascular (DCV) seja a principal causa de morte das mulheres no Uruguai, elas não a percebem. Objetivos: o objetivo deste estudo foi avaliar a percepção, conhecimento e comportamentos de prevenção de DCV entre mulheres por faixa etária, nível socioeconômico (NSE) e região, bem como o conhecimento de fatores de risco, sintomas, doenças cardíacas e comportamentos saudáveis para o coração. Método e resultado: em 2020, 700 mulheres entre 20 e 70 anos, residentes no Uruguai, foram entrevistadas via web (Montevidéu: 301, interior do país: 399). A publicidade foi agendada nas redes sociais, convocando a população alvo a participar da referida pesquisa através do preenchimento de um inquérito autoaplicável, obtendose um conjunto de casos com distribuição semelhante à população geral em termos de NSE e idade. As mulheres pesquisadas perceberam a DCV como principal problema de saúde (PS) em 10% e como principal CM em 18%. As mulheres de Montevidéu vs. interior apresentaram níveis mais elevados de percepção (PS: 13% vs. 7%-CM: 20% vs. 17%); bem como as de NSE alto vs. as de médiobaixo (PS: 17% vs. 8%-CM: 29% vs. 14%). A percepção e o conhecimento sobre DCV são baixos, sendo as mulheres jovens as menos informadas (pouco/muito pouco: 62%). Os médicos informam pouco sobre síntomas (23%) e prevenção (48%). Conclusão: a percepção das mulheres pesquisadas sobre DCV é baixa, com diferenças por idade, NSE e região. Os médicos informam pouco sobre esse tema durante as consultas clínicas. É necessário um esforço contínuo para melhorar a percepção das mulheres sobre as DCV em seu próprio gênero, tentando atingir principalmente as populações de maior risco.


Subject(s)
Humans , Female , Adult , Middle Aged , Aged , Young Adult , Perception , Cardiovascular Diseases/prevention & control , Health Knowledge, Attitudes, Practice , Socioeconomic Factors , Uruguay/epidemiology , Cardiovascular Diseases/epidemiology , Cross-Sectional Studies , Risk Factors , Health Surveys , Cause of Death , Age Distribution
8.
Arch. pediatr. Urug ; 93(1): e801, jun. 2022. tab
Article in Spanish | LILACS, BNUY, UY-BNMED | ID: biblio-1383633

ABSTRACT

Se presentan, en un trabajo conjunto, las recomendaciones para la evaluación cardiovascular de personas menores de 35 años que realizan ejercicio y deportes. Se establecen pautas en cuanto a la valoración y la habilitación que tendrá dicha evaluación, quiénes estarán a cargo de su realización y cuáles son los componentes fundamentales de una correcta valoración cardiovascular. Se toman en cuenta los antecedentes familiares y personales, el examen físico exhaustivo y se considera conveniente la realización del ECG como parte integrante obligatorio. Se hacen referencia a otros estudios funcionales como opcionales, así como la posible derivación a los especialistas cuando se considere necesario.


We hereby present joint recommendations for cardiovascular assessment of people under 35 years of age who do exercise and sports. We set the guidelines regarding evaluation and score of such assessment, the agents in charge of implementing it and the main components of a correct cardiovascular assessment. We take into account the family and personal history and perform a comprehensive physical examination as well as an ECG as a mandatory part of this comprehensive approach. We mention other optional functional studies as well as reference to specialists whenever necessary.


Apresentamos através dum paper conjunto recomendações para a avaliação cardiovascular de pessoas de 35 anos de idade que praticam exercício e esportes. Estabelecem-se as diretrizes quanto à qualificação dessa avaliação, quem a realizará e quais são os componentes fundamentais de uma correta avaliação cardiovascular. Consideramos obrigatório incluir a história familiar e pessoal, o exame físico exaustivo e o ECG opcional. Referimo-nos a outros estudos funcionais opcionais, assim como ao possível encaminhamento para especialistas quando for necessário.


Subject(s)
Humans , Child , Adolescent , Adult , Young Adult , Sports , Cardiovascular Diseases/prevention & control , Exercise , Physical Examination , Cardiovascular Diseases/diagnosis , Death, Sudden, Cardiac/prevention & control , Electrocardiography , Medical History Taking
10.
Int. j. cardiovasc. sci. (Impr.) ; 35(1): 68-79, Jan.-Feb. 2022. tab
Article in English | LILACS | ID: biblio-1356304

ABSTRACT

Abstract Background The long incubation periods of cardiovascular diseases offer opportunities for controlling risk factors. In addition, preventive interventions in childhood are more likely to succeed because lifestyle habits become ingrained as they are repeated. Objective To investigate the effects of recreational physical activities, in combination or not with a qualitative nutritional counseling, in cardiometabolic risk factors of students with dyslipidemia and abdominal obesity. Methods Students (8-14 years old) were randomly divided into three groups (n=23 each): i ) Control; ii ) PANC, students undergoing Physical Activity and Nutritional Counseling, and iii ) PA, students submitted to Physical Activity, only. Blood samples (12-h fasting) were collected for biochemical analysis and anthropometric markers were also assessed. Two-Way RM-ANOVA and Holm-Sidak's test, and Friedman ANOVA on Ranks and Dunn's test were applied. P ≤ 0.05 was considered significant. Effect sizes were evaluated by Hedges' g and Cliff's δ for normal and non-Gaussian data, respectively. Results Compared to the control group and to baseline values, both interventions caused significant average reductions in total cholesterol (11%; p <0.001), LDL-c (19%; p=0.002), and non-HDL-c (19%; p=0.003). Furthermore, students in the PANC group also experienced a significant decrease in body fat compared to baseline (p=0.005) and to control (5.2%; g=0.541). Conclusions The proposed strategies were effective to reduce cardiometabolic risk factors in children and adolescents. The low cost of these interventions allows the implementation of health care programs in schools to improve the students' quality of life.


Subject(s)
Humans , Male , Female , Child , Adolescent , Food and Nutrition Education , Dyslipidemias/prevention & control , Obesity, Abdominal/prevention & control , Cardiometabolic Risk Factors , Life Style , Quality of Life , Students , Cardiovascular Diseases/prevention & control , Exercise , Delivery of Health Care , Dyslipidemias/diet therapy , Adolescent Nutrition , Obesity, Abdominal/diet therapy
12.
Arq. bras. cardiol ; 118(1): 68-74, jan. 2022. tab
Article in English, Portuguese | LILACS | ID: biblio-1360106

ABSTRACT

Resumo Fundamento Apesar da grande proporção de octogenários com embolia pulmonar aguda, há pouca informação indicando a estratégia de manejo ideal, especialmente medidas terapêuticas, como a terapia lítica. Objetivos O número de pacientes idosos diagnosticados com embolia pulmonar aguda aumenta constantemente. Porém, o papel do tratamento trombolítico não está claramente definido entre os octogenários. Nosso objetivo é avaliar a efetividade da terapia lítica em pacientes octogenários diagnosticados com embolia pulmonar. Métodos Cento e quarenta e oito indivíduos (70,3% de mulheres, n=104) com mais de 80 anos foram incluídos no estudo. Os pacientes foram divididos em dois grupos: tratamento trombolítico versus não-trombolítico. As taxas de mortalidade hospitalar e episódios de sangramento foram definidos como desfechos do estudo. Valor de p <0,05 foi considerado como estatisticamente significativo. Resultados A mortalidade hospitalar reduziu significativamente no grupo trombolítico em comparação ao não-trombolítico (10,5% vs. 24,2%; p=0,03). Episódios de sangramento menores foram mais comuns no braço que recebeu o tratamento trombolítico, mas grandes hemorragias não diferiram entre os grupos (35,1% vs. 13,2%, p<0,01; 7% vs. 5,5% p=0,71, respectivamente). O escore de PESI alto (OR: 1,03 IC95%; 1,01-1,04 p<0,01), a terapia trombolítica (OR: 0,15 IC95%; 0,01-0,25, p< 0,01) e níveis altos de troponina (OR: 1,20 IC95%; 1,01-1,43, p=0,03) estiveram independentemente associados a taxas de mortalidade hospitalar na análise de regressão multivariada. Conclusão A terapia trombolítica esteve associada à mortalidade hospitalar reduzida em detrimento do aumento geral das complicações de sangramento em octogenários.


Abstract Background Despite the high proportion of octogenarians with acute pulmonary embolism, there is little information indicating the optimal management strategy, mainly therapeutic measures, such as lytic therapy. Objectives The number of elderly patients diagnosed with acute pulmonary embolism increases constantly. However, the role of thrombolytic treatment is not clearly defined among octogenarians. Our objective is to evaluate the effectiveness of lytic therapy in octogenarian patients diagnosed with pulmonary embolism. Methods One hundred and forty eight subjects (70.3% women, n=104) aged more than eighty years were included in the study. The patients were divided in two groups: thrombolytic versus non-thrombolytic treatment. In-hospital mortality rates and bleeding events were defined as study outcomes. P-value <0.05 was considered as statistical significance. Results In-hospital mortality decreased significantly in the thrombolytic group compared to the non-thrombolytic group (10.5% vs. 24.2% p=0.03). Minor bleeding events were more common in the arm that received thrombolytic treatment, but major hemorrhage did not differ between the groups (35.1% vs. 13.2%, p<0.01; 7% vs. 5.5% p=0.71, respectively). High PESI score (OR: 1.03 95%CI; 1.01-1.04 p<0.01), thrombolytic therapy (OR: 0.15 95%CI; 0.01-0.25, p< 0.01) and high troponin levels (OR: 1.20 95%CI; 1.01-1.43, p=0.03) were independently associated with in-hospital mortality rates in the multivariate regression analysis. Conclusion Thrombolytic therapy was associated with reduced in-hospital mortality at the expense of increased overall bleeding complications in octogenarians.


Subject(s)
Humans , Child , Adolescent , Cardiovascular Diseases/etiology , Cardiovascular Diseases/prevention & control , Metabolic Syndrome/epidemiology , Pediatric Obesity/therapy , Body Composition , Weight Loss/physiology , Body Mass Index , Atrial Natriuretic Factor/metabolism
13.
Arq. bras. cardiol ; 118(1): 33-40, jan. 2022. tab, graf
Article in English, Portuguese | LILACS | ID: biblio-1360114

ABSTRACT

Resumo Fundamento A ação do peptídeo natriurético atrial (ANP) na natriurese, diurese e vasodilatação, resistência à insulina, fígado, rim e tecido adiposo pode contribuir para o desenvolvimento metabólico e cardiovascular saudável. Embora o nível circulante de ANP seja reduzido em pacientes com obesidade, sua resposta à perda de peso ainda é pouco explorada em populações pediátricas. Objetivo Avaliar os efeitos das variações do ANP em resposta à intervenção interdisciplinar para perda de peso na Síndrome Metabólica (SMet) e nos riscos cardiometabólicos em adolescentes com obesidade. Métodos 73 adolescentes com obesidade participaram de uma terapia interdisciplinar para perda de peso de 20 semanas, incluindo uma abordagem clínica, nutricional, psicológica e de exercícios físicos. A composição corporal, análises bioquímicas e pressão sanguínea foram avaliadas. A SMet foi classificada de acordo com a Federação Internacional de Diabetes (IDF) (2007). Após o tratamento, os voluntários foram divididos de acordo com os níveis de plasma do ANP aumento (n=31) ou ANP redução (n=19). Resultados Ambos os grupos apresentaram redução significativa de peso corporal, índice de massa corporal (IMC) e circunferências de cintura, pescoço e quadril (CC, CP e CQ, respectivamente), e aumento da massa livre de gordura (MLG). É interessante observar que houve uma redução significativa na gordura corporal, na razão de TG/HDL-c e na prevalência de SMet (de 23% para 6%) somente no grupo com ANP aumento. Conclusão Este estudo sugere que o aumento nos níveis séricos de ANP após a terapia para perda de peso pode estar associado a melhorias nos riscos cardiometabólicos e na prevalência reduzida de SMet em adolescentes com obesidade.


Abstract Background The action of atrial natriuretic peptide (ANP) on natriuresis, diuresis and vasodilatation, insulin resistance, liver, kidney, and adipose tissue may contribute to the healthy metabolic and cardiovascular development. Even though the circulating level of ANP is reduced in patients with obesity, its response to weight loss remains poorly explored in pediatric populations. Objective To evaluate the effects of ANP variations in response to interdisciplinary weight loss intervention on metabolic syndrome (MetS) and cardiometabolic risks in adolescents with obesity. Methods 73 adolescents with obesity attended a 20-week clinical interdisciplinary weight loss therapy including clinical, nutritional, psychological and exercise training approach. Body composition, biochemical analyses and blood pressure were evaluated. MetS was classified according to the International Diabetes Federation (IDF) (2007). After the treatment, volunteers were divided according to Increasing (n=31) or Decreasing (n=19) ANP plasma levels. Results Both groups present significant reduction of body weight, Body Mass Index (BMI), waist, neck and hip circumferences (WC, NC and HC, respectively) and increasing fat-free mass (FFM). Interestingly, a significant reduction in body fat, TG/HDL-c ratio and MetS prevalence (from 23% to 6%) was observed in the Increased ANP group only. Conclusion This study suggests that an increase in ANP serum levels after weight loss therapy could be associated with improvements in cardiometabolic risks and the reduced prevalence of MetS in adolescents with obesity.


Subject(s)
Humans , Child , Adolescent , Cardiovascular Diseases/etiology , Cardiovascular Diseases/prevention & control , Metabolic Syndrome/epidemiology , Pediatric Obesity/therapy , Body Composition , Weight Loss/physiology , Body Mass Index , Atrial Natriuretic Factor/metabolism
14.
Article in Chinese | WPRIM | ID: wpr-940987

ABSTRACT

OBJECTIVE@#To evaluate the effectiveness of different screening strategies for type 2 diabetes to prevent cardiovascular disease in a community-based Chinese population from economically developed areas based on the Chinese electronic health records research in Yinzhou (CHERRY) study.@*METHODS@#A Markov model was used to simulate different systematic diabetes screening strategies, including: (1) screening among Chinese adults aged 40-70 years recommended by the 2020 Chinese Guideline for the prevention and Treatment of Type 2 Diabetes (Strategy 1); (2) screening among Chinese adults aged 35 to 70 years recommended by the 2022 American Diabetes Association Standard of Medical Care in Diabetes (Strategy 2); and (3) screening among Chinese adults aged 35-70 years with overweight or obesity recommended by the 2021 United States Preventive Services Task Force Recommendation Statement on Screening for Prediabetes and Type 2 Diabetes (Strategy 3). According to the guidelines, individuals who were screened positively (fasting plasma glucose ≥ 7.0 mmol/L) would be introduced to intensive glycemic targets management (glycated hemoglobin < 7.0%).The Markov model simulated different screening scenarios for ten years (cycles) with parameters mainly from the CHERRY study or published literature. Number of cardiovascular disease events or deaths could be prevented and number needed to screen (NNS) were calculated to compare the effectiveness of the different strategies. One-way sensitivity analysis on the sensitivity of screening methods and probabilistic sensitivity analysis on uncertainties of diabetes incidence, the sensitivity of screening methods, and intensive glycemic management effects were conducted.@*RESULTS@#Totally 289 245 Chinese adults aged 35-70 years without cardiovascular diseases or diagnosed diabetes at baseline were enrolled. In terms of the number of cardiovascular disease events could be prevented, Strategy 1 for systematic diabetes screening among the adults aged 35-70 years was 222 (95%UI: 180-264), Strategy 2 for systematic diabetes screening among the adults aged 40-70 years was 227 (95%UI: 185-271), and Strategy 3 for systematic diabetes screening among the adults aged 35-70 years with obesity or overweight (body mass index ≥ 24 kg/m2) was 131 (95%UI: 98-164), compared with opportunistic screening. NNS per cardiovascular disease event for the strategies 1, 2 and 3 were 1 184 (95%UI: 994-1 456), 1 274 (95%UI: 1 067-1 564) and 814 (95%UI: 649-1 091), respectively. Compared with Strategy 1, NNS per cardiovascular disease event for Strategy 2 increased by 90 (95%UI: -197-381) with similar effectiveness of cardiovascular prevention; however, NNS per cardiovascular disease event for Strategy 3 was reduced by 460 (95%UI: 185-724) in contrast to the Strategy 2, suggesting that the Strategy 3 was more efficient. The results were consistent in multiple sensitivity analyses.@*CONCLUSION@#Systematic screening for diabetes based on the latest guidelines in economically developed areas of China can reduce cardiovascular events and deaths. However, merely lowering the starting age of screening from 40 to 35 years seems ineffective for preventing cardiovascular disease, while screening strategy for Chinese adults aged 35-70 years with overweight or obesity is recommended to improve efficiency.


Subject(s)
Adult , Cardiovascular Diseases/prevention & control , China/epidemiology , Cost-Benefit Analysis , Diabetes Mellitus, Type 2/prevention & control , Humans , Mass Screening/methods , Obesity , Overweight , United States
15.
Article in Chinese | WPRIM | ID: wpr-940986

ABSTRACT

OBJECTIVE@#To evaluate the effectiveness of statin treatment strategies based on risk assessment for the primary prevention of cardiovascular diseases by the Western guidelines in a community-based Chinese population from economically developed areas using data from the Chinese electronic health records research in Yinzhou (CHERRY) study.@*METHODS@#A Markov model was used to evaluate the effectiveness of the following statin treatment strategies, including: (1) usual care without cardiovascular risk assessment(Strategy 0); (2) using the World Health Organization (WHO) non-laboratory-based risk charts with statin treatment for high-risk group (risk ≥ 20%) (Strategy 1); (3) using the WHO laboratory-based risk charts with statin treatment for high-risk group (risk ≥ 20%) (Strategy 2); and (4) using the Prediction for Atherosclerotic cardiovascular disease Risk in China (China-PAR) model with statin treatment for high-risk group (risk ≥ 10%, Strategy 3). According to the guidelines, adults in the medium-risk group received lifestyle intervention, and adults in the high-risk group received life-style intervention and statin treatment under these strategies. The Markov model simulated different strategies for ten years (cycles) using parameters from the CHERRY study, published data, meta-analyses and systematic reviews for Chinese. The number of cardiovascular events or deaths, as well as the number need to treat (NNT) with statin per cardiovascular event or death prevented, were calculated to compare the effectiveness of different strategies. One-way sensitivity analysis on the uncertainty of incidence rate of cardiovascular diseases, and probabilistic sensitivity analysis on the uncertainty of hazard ratios of interventions were conducted.@*RESULTS@#Totally 225 811 Chinese adults aged 40-79 years without cardiovascular diseases at baseline were enrolled. In contrast to the usual care without risk assessment-based statin treatment strategy, Strategy 1 using the WHO non-laboratory-based risk charts could prevent 3 482 [95% uncertainty interval (UI): 2 110-4 661] cardiovascular events, Strategy 2 using the WHO laboratory-based risk charts could prevent 3 685 (95%UI: 2 255-4 912) events, and Strategy 3 using the China-PAR model could prevent 3 895 (95%UI: 2 396-5 181) events. NNTs with statin per cardiovascular event prevented were 22 (95%UI: 14-54), 21 (95%UI: 14-52), and 27 (95%UI: 17-67), respectively. Strategy 3 could prevent more cardiovascular events, while Strategies 1 and 2 required fewer numbers need to treat with statin per cardiovascular event prevented. The results were consistent in the sensitivity analyses.@*CONCLUSION@#The statin treatment strategies based on risk assessment for the primary prevention of cardiovascular diseases recommended by the Western guidelines could achieve substantive health benefits in adults from developed areas of China. Using the China-PAR model for cardiovascular risk assessment could prevent more cardiovascular diseases while using the WHO risk charts seems more efficient.


Subject(s)
Adult , Cardiovascular Diseases/prevention & control , China/epidemiology , Cost-Benefit Analysis , Humans , Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use , Primary Prevention
16.
Chinese Journal of Stomatology ; (12): 462-473, 2022.
Article in Chinese | WPRIM | ID: wpr-935888

ABSTRACT

With the aging process of population in the society, the prevalence of cardiovascular diseases (CVD) in China is increasing continuously and the number of dental patients with CVD is increasing gradually too. Due to the lack of guidelines for dental patients with CVD in our country, how to implement standardized preoperative evaluation and perioperative risk prevention remains a problem to be solved for dentists at present. The present expert consensus was reached by combining the clinical experiences of the expert group of the Fifth General Dentistry Special Committee, Chinese Stomatological Association and respiratory and cardiology experts in diagnosis and treatment for CVD patients, and by systematically summarizing the relevant international guidelines and literature regarding the relationship between CVD and oral diseases and the diagnosis and treatment of dental patients with heart failure, hypertension and antithrombotic therapy. The consensus aims to provide, for the dental clinicians, the criteria on diagnosis and treatment of CVD in dental patients in China so as to reduce the risk and complications, and finally to improve the treatment levels of dental patients with CVD in China.


Subject(s)
Cardiovascular Diseases/prevention & control , China/epidemiology , Consensus , Dental Care , Humans , Oral Medicine
17.
Article in English | WPRIM | ID: wpr-928841

ABSTRACT

BACKGROUND@#Although the age-adjusted incidence and mortality of cancer and cardiovascular disease (CVD) have been decreasing steadily in Japan, both diseases remain major contributors to morbidity and mortality along with the aging society. Herein, we aim to provide a prescription of 10 health tips for long and healthy life named the "Lifelong Health Support 10 (LHS10)."@*METHOD@#The LHS10 was developed by the preventive medicine specialists at the National Cerebral and Cardiovascular Center in Suita, where it has been used for health guidance to prevent CVD, cancer, and cognitive decline in addition to their major risk factors such as hypertension, diabetes, and obesity. It consisted of the lifestyle modification recommendations of the 2014 Japanese Society of Hypertension guidelines and the 2017 Japan Atherosclerosis Society Guidelines for preventing atherosclerotic CVD. Further, it came in line with other international lifestyle modification guidelines. In this narrative review, we summarized the results of several Japanese epidemiological studies investigating the association between the LHS10 items and the risk of cancer, CVD, and other chronic diseases including dementia, diabetes, and chronic kidney disease.@*RESULTS@#The LHS10 included avoiding smoking and secondhand smoke exposure, engaging in physical activity, refraining from excessive alcohol drinking, reducing fried foods and sugary soft drinks, cutting salt in food, consuming more vegetables, fruits, fish, soy foods, and fibers, and maintaining proper body weight. All items of the LHS10 were shown to reduce the risk of cancer, CVD, and other chronic diseases.@*CONCLUSIONS@#The LHS10 can be a helpful tool for health guidance.


Subject(s)
Cardiovascular Diseases/prevention & control , Humans , Hypertension/prevention & control , Japan/epidemiology , Life Style , Neoplasms , Prescriptions , Risk Factors
18.
Article in Chinese | WPRIM | ID: wpr-927321

ABSTRACT

Atherosclerotic cardiovascular disease is the general name of a series of diseases based on atherosclerosis. With the development of the social economy and the progress of population aging in China, the burden of atherosclerotic cardiovascular disease is increasing. However, in recent years some clinical studies have proved that the traditional blood lipid indicators, including low-density lipoprotein cholesterol, have some limitations in the risk control of atherosclerotic cardiovascular disease, and the blood lipid indicators need to be further supplemented and improved. This consensus expounds non-traditional blood lipid indexes from the perspectives of test and clinic, mainly including apolipoprotein B and lipoprotein a, non-high density lipoprotein cholesterol and lipoprotein residue, and non-fasting blood lipid. This consensus systematically expounds the pathophysiological mechanism of non-traditional blood lipid indexes, the relationship with cardiovascular disease, detection methods and performance, intervention, control and application in the state of cardiovascular disease, and gives the corresponding clinical expert suggestion.


Subject(s)
Atherosclerosis/prevention & control , Cardiovascular Diseases/prevention & control , Consensus , Humans , Lipids , Lipoproteins , Risk Factors
19.
Rev. latinoam. enferm. (Online) ; 30: e3512, 2022. tab, graf
Article in Portuguese | LILACS, BDENF | ID: biblio-1365888

ABSTRACT

Resumo Objetivo Validar um material educativo digital interativo no formato de livro eletrônico sobre prevenção e redução do risco cardiovascular na perspectiva das pessoas vivendo com vírus da imunodeficiência humana. Método Trata-se de um estudo metodológico baseado na teoria de pesquisa de avaliação, do tipo análise de resultados, que envolve produção tecnológica. Os dados foram coletados em todo o Brasil por meio de um questionário virtual composto por itens para avaliação geral, visual, linguagem, usabilidade, conteúdo e aparência do material educativo. Para atestar a validade, adotou-se o Índice de Concordância mínimo de 80%. Resultados Participaram do estudo 309 pessoas vivendo com vírus da imunodeficiência humana, a maioria (84,3%) do sexo masculino, com idade entre 19 e 65 anos e ensino superior completo (29,3%). Mais de 90% dos participantes avaliaram o livro como adequado para tirar dúvidas e realizar cuidados preventivos à saúde cardiovascular. Todos os itens avaliados alcançaram índice acima de 0,80. A avaliação geral de todos os itens alcançou média de 0,92, sendo a avaliação geral (0,97) e o conteúdo (0,94). Conclusão O material educativo mostrou-se válido, adequado e pertinente para promover a alfabetização em saúde, e poderá contribuir com a promoção da saúde e prevenção de doenças cardiovasculares.


Abstract Objective To validate interactive digital educational material in the form of an electronic book about the prevention and reduction of cardiovascular risk from the perspective of people living with the Human Immunodeficiency Virus. Method This is a methodological study based on the theory of evaluation research, of the results analysis type, which involves technological production. The data were collected throughout Brazil by means of a virtual questionnaire consisting of items for general, visual, language, usability, content and appearance assessment of the educational material. A minimum Agreement Index of 80% was adopted in order to certify validity. Results 309 individuals living with the Human Immunodeficiency Virus participated in the study, the majority (84.3%) being male, aged between 19 and 65 years old and with complete higher education (29.3%). More than 90% of the participants assessed the book as suitable for solving doubts and providing preventive care for cardiovascular health. All the items evaluated reached an index above 0.80. The general evaluation of all the items reached a mean of 0.92, with general assessment (0.97) and content assessment (0.94). Conclusion The educational material proved to be valid, adequate and relevant to promote literacy in health, and could contribute to health promotion and to the prevention of cardiovascular diseases.


Resumen Objetivo Validar un material educativo digital interactivo en forma de libro electrónico sobre prevención y reducción del riesgo cardiovascular desde la perspectiva de las personas que viven con el virus de la inmunodeficiencia humana. Método Se trata de un estudio metodológico basado en la teoría de la investigación evaluativa, del tipo análisis de resultados, que incluye producción tecnológica. Los datos fueron recolectados en todo Brasil a través de un cuestionario virtual compuesto por ítems de evaluación general e ítems que evalúan el aspecto visual, el lenguaje, la usabilidad, el contenido y la apariencia del material educativo. Para comprobar la validez se adoptó un Índice de Concordancia mínimo del 80%. Resultados Participaron en el estudio 309 personas que viven con el virus de la inmunodeficiencia humana, la mayoría (84,3%) era del sexo masculino, tenía entre 19 y 65 años y estudios superiores completos (29,3%). Más del 90% de los participantes calificaron el libro como adecuado para aclarar dudas y realizar cuidados preventivos para la salud cardiovascular. Todos los ítems evaluados alcanzaron un índice superior a 0,80. La evaluación general de todos los ítems alcanzó una media de 0,92, la evaluación general fue 0,97 y la de contenido 0,94. Conclusión El material educativo demostró ser válido, adecuado y relevante para promover la alfabetización en salud y puede contribuir a la promoción de la salud y a la prevención de enfermedades cardiovasculares.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Cardiovascular Diseases/prevention & control , HIV Infections , Health Education , Acquired Immunodeficiency Syndrome , Educational Technology , Validation Study , Health Literacy
20.
Cad. Saúde Pública (Online) ; 38(8): e00266221, 2022. tab, graf
Article in English | LILACS | ID: biblio-1384286

ABSTRACT

This study aims to assess the non-additivity effects of gender, race, and schooling on ideal cardiovascular health among participants of the Brazilian Longitudinal Study of Adult Health - ELSA-Brasil. This is a cross-sectional study using data from the baseline of ELSA-Brasil, conducted from 2008 to 2010. The American Heart Association defined a score of ideal cardiovascular health (ICH) as the sum of indicators for the presence of seven favorable health factors and behaviors: non-smoking, ideal body mass index, physical activity and healthy diet, adequate levels of total cholesterol, normal blood pressure, and absence of diabetes mellitus. Multiplicative and additive interactions between gender, race, and schooling were assessed using the Poisson regression model to discuss intersectionality. The mean cardiovascular health score was 2.49 (SD = 1.31). This study showed a positive interaction between gender and schooling (women with high school and higher education) in both additive and multiplicative scales for the score of ideal cardiovascular health. We observed a trend towards higher mean values of cardiovascular health for increased schooling, with a marked difference among women. The lowest cardiovascular health scores observed reinforce the importance of understanding the psychosocial experiences that influence health attitudes, access to health care, and healthy lifestyle choices, which affect ICH, to reduce inequities in health and propose more adequate public policies that assist and prevent cardiovascular diseases.


Este estudo visa avaliar a não-aditividade dos efeitos de gênero, raça e escolaridade na saúde cardiovascular ideal entre os participantes do Estudo Longitudinal de Saúde do Adulto - ELSA-Brasil. Trata-se de um estudo transversal utilizando dados da linha de base do ELSA-Brasil, realizado entre 2008-2010. A Associação Americana do Coração definiu a pontuação de saúde cardiovascular ideal (ICH) como a soma dos indicadores da presença de sete fatores e comportamentos favoráveis à saúde: não fumante, índice de massa corporal ideal, atividade física e dieta saudável, níveis adequados de colesterol total, pressão arterial normal e ausência de diabetes mellitus. Interações multiplicativas e aditivas entre gênero, raça e escolaridade foram avaliadas usando o modelo de Poisson, como uma abordagem para discutir a interseccionalidade. A pontuação média de saúde cardiovascular foi de 2,49 (DP = 1,31). Este estudo encontrou uma interação positiva entre gênero e escolaridade (mulheres com Ensino Médio e Superior), tanto na escala aditiva quanto na escala multiplicativa, para a pontuação de saúde cardiovascular ideal. Houve tendência para maiores valores médios de saúde cardiovascular com o aumento da escolaridade, com diferença acentuada entre as mulheres. As pontuações mais baixas de saúde cardiovascular observadas reforçam a importância de compreender-se as experiências psicossociais que influenciam as atitudes em relação aos serviços de saúde, ao acesso à saúde e às escolhas de estilo de vida saudável, que afetam a ICH, para reduzir as desigualdades em saúde e propor políticas públicas mais adequadas como uma estratégia de assistência e prevenção das doenças cardiovasculares.


Este estudio tiene como objetivo evaluar los efectos no aditivos de género, raza y educación en la salud cardiovascular ideal entre los participantes del Estudio Longitudinal de Salud del Adulto -ELSA-Brasil. Se trata de un estudio transversal realizado a partir de datos de línea de base de ELSA-Brasil entre 2008-2010. La Asociación Americana del Corazón definió el puntaje ideal de salud cardiovascular (ICH) como la suma de indicadores de la presencia de siete factores y comportamientos favorables a la salud: no fumador, índice de masa corporal ideal, actividad física y alimentación saludable, niveles adecuados de colesterol total, presión arterial normal y ausencia de diabetes mellitus. Las interacciones multiplicativas y aditivas entre género, raza y educación se evaluaron utilizando el modelo de Poisson como un enfoque para discutir la interseccionalidad. La puntuación media de salud cardiovascular fue de 2,49 (DE = 1,31). Este estudio encontró una interacción positiva entre el género y la educación (mujeres con educación secundaria y universitaria), tanto en la escala aditiva como en la escala multiplicativa, para puntajes ideales de salud cardiovascular. Hubo una tendencia a valores medios más altos de salud cardiovascular conforme aumenta el nivel de educación, con una marcada diferencia entre las mujeres. Los puntajes más bajos de salud cardiovascular refuerzan la importancia de comprender las experiencias psicosociales que influyen en las actitudes hacia la salud, el acceso a la salud y la elección de un estilo de vida saludable, que inciden en el ICH, para reducir las desigualdades en salud y proponer políticas públicas más adecuadas como estrategia de asistencia y prevención de enfermedades cardiovasculares.


Subject(s)
Humans , Female , Adult , Cardiovascular Diseases/prevention & control , Brazil , Cross-Sectional Studies , Risk Factors , Longitudinal Studies , Educational Status
SELECTION OF CITATIONS
SEARCH DETAIL