ABSTRACT
Introducción. La resonancia magnética nuclear es un estudio ampliamente usado, que se ha convertido actualmente en una herramienta imprescindible para la toma de decisiones terapéuticas en los pacientes con cáncer de recto. El objetivo de este estudio fue esclarecer si los informes actuales cumplen con las recomendaciones internacionales respecto a los ítems que deben incluir para tomar mejores decisiones en el manejo y el seguimiento de los pacientes. Métodos. Estudio observacional, retrospectivo, de una cohorte de seguimiento de pacientes con cáncer de recto a quienes se les realizó resonancia magnética nuclear para estadificación o re-estadificación posterior a una terapia neoadyuvante, entre julio de 2020 y julio del 2022, en 2 centros de referencia de la ciudad de Medellín, Colombia. Resultados. En total se evaluaron 205 informes de resonancia magnética nuclear tomadas en pacientes con cáncer de recto, de los cuales el 50,2 % fueron de diagnóstico inicial sin terapia neoadyuvante y el 49,7 % fueron informes de re-estadificación posterior a terapia neoadyuvante. Se evaluaron 13 ítems de los reportes de las resonancias. Se encontró que un 2 % de los reportes fueron de alta calidad, 14,6 % de moderada calidad y 83,4 % de baja calidad. Conclusiones. La mayoría de los reportes de resonancia magnética nuclear en pacientes con cáncer de recto son de baja calidad, por lo tanto, serán necesarias estrategias que mejoren la comunicación, la estandarización y la calidad de los estudios.
Introduction. Magnetic resonance imaging (MRI) is the widely used study, which today has become an essential tool for therapeutic decisions in patients with rectal cancer. The objective of this study was to clarify whether current reports comply with international recommendations regarding the items they should have to make better decisions in the patients management and follow-up. Methods. Observational, retrospective study of a follow-up cohort of patients with rectal cancer who underwent MRI for staging or re-staging after neoadjuvant therapy, between July 2020 and July 2022, in two reference centers in the city of Medellín, Colombia. Results. In total, 205 MRI reports in patients with rectal cancer were reviewed, of which 50.2% were initial diagnosis without neoadjuvant therapy and 49.7% were reports of restaging after neoadjuvant therapy; 13 items from the MRI reports were evaluated. It was found that 2% of the reports were of high quality, 14.6% of moderate quality and 83.4% of low quality. Conclusions. Most MRI reports in patients with rectal cancer are of low quality; therefore, strategies will be necessary to improve communication, standardization and quality of the studies.
Subject(s)
Humans , Rectal Neoplasms , Magnetic Resonance Imaging , Technology Assessment, Biomedical , Diagnostic Imaging , Colorectal Surgery , Neoadjuvant TherapyABSTRACT
The rupture of the anterior cruciate ligament is common during physical activities; however, when associated with a multiple ligament injury, it represents an uncommon condition. The diagnosis of this injury is commonly delayed or missed. Consequently, the incidence of this injury may in fact be higher than reported. We present a case of a 27-year-old man with complete tear of the anterior cruciate ligament and of the medial collateral ligament and partial tear of the posterior cruciate, lateral collateral and patellar ligaments treated surgically.
A ruptura do ligamento cruzado anterior é comum durante atividades físicas; entretanto, quando associada a lesão ligamentar múltipla, representa uma condição incomum. O diagnóstico desta lesão é comumente tardio ou esquecido. Consequentemente, a incidência desta lesão pode de facto ser superior à relatada. Apresentamos o caso de um homem de 27 anos com ruptura completa do ligamento cruzado anterior e do ligamento colateral medial e ruptura parcial dos ligamentos cruzado posterior, colateral lateral e patelar tratados cirurgicamente.
La rotura del ligamento cruzado anterior es común durante las actividades físicas; sin embargo, cuando se asocia con una lesión de múltiples ligamentos, representa una condición poco común. El diagnóstico de esta lesión comúnmente se retrasa o se pasa por alto. En consecuencia, la incidencia de esta lesión puede ser mayor de lo informado. Presentamos el caso de un varón de 27 años con rotura completa del ligamento cruzado anterior y del ligamento colateral medial y rotura parcial de los ligamentos cruzado posterior, colateral lateral y rotuliano tratados quirúrgicamente.
Subject(s)
Humans , Male , Adult , Magnetic Resonance Imaging , Ligaments, Articular/diagnostic imaging , Anterior Cruciate Ligament/diagnostic imaging , Posterior Cruciate Ligament/diagnostic imaging , Patellar Ligament/diagnostic imaging , Medial Collateral Ligament, Knee/diagnostic imagingABSTRACT
Wunderlich syndrome is a rare and life-threatening disease characterized by nontraumatic renal hemorrhage in the subscapular and perinephritic space. It is a very rare clinical entity in pregnancy and so far there is no clear guidance on how to manage this condition during pregnancy. We report the case of a 34-year-old patient with a 29+2-week pregnancy who developed a Wunderlich syndrome, which was successfully treated, preserving the pregnancy until its end.
El síndrome de Wunderlich es una enfermedad con poca incidencia y potencialmente mortal que se caracteriza por una hemorragia renal no traumática en el espacio subescapular y perinefrítico. Es una entidad clínica muy rara en el embarazo y hasta el momento no existe una guía clara sobre el manejo de esta afección durante el embarazo. Reportamos el caso de una paciente de 34 años cursando embarazo de 29+2 semanas quien manifestó un síndrome de Wunderlich el cuál fue tratado con éxito logrando preservar el embarazo hasta su término.
Subject(s)
Humans , Female , Pregnancy , Adult , Pregnancy Complications, Neoplastic/pathology , Angiomyolipoma/pathology , Kidney Neoplasms/pathology , Pregnancy Complications, Neoplastic/surgery , Pregnancy Complications, Neoplastic/diagnosis , Shock, Hemorrhagic/etiology , Syndrome , Magnetic Resonance Imaging , Angiomyolipoma/surgery , Angiomyolipoma/diagnostic imaging , Flank Pain/etiology , Delivery, Obstetric , Embolization, Therapeutic , Kidney Neoplasms/surgery , Kidney Neoplasms/diagnostic imagingABSTRACT
La obstrucción nasal se caracteriza por un flujo aéreo insuficiente y una resistencia aumentada en las cavidades nasales, afectando la calidad de vida y el sueño de los pacientes. Este estudio busca comparar la eficacia del tratamiento médico y quirúrgico en pacientes con obstrucción nasal, utilizando evaluaciones subjetivas (escalas NOSE y EVA) y objetivas (rinomanometría anterior activa). El siguiente es un estudio experimental y prospectivo con corte longitudinal, realizado en el Hospital de Clínicas, Paraguay. Se incluyeron 40 pacientes con obstrucción nasal, divididos en grupos de tratamiento médico (corticoides nasales) y quirúrgico (turbinoplastia, septumplastia o ambos). Se evaluaron pre y post tratamiento con las escalas NOSE y EVA, y la rinomanometría anterior activa. La muestra incluyó 52.5% hombres y 47.5% mujeres, con una edad promedio de 32.18±11.59 años. La principal causa de obstrucción nasal fue la rinitis crónica (62.5%). Los tratamientos mostraron mejoras significativas en las evaluaciones subjetivas y objetivas. En el grupo médico, la EVA mejoró en 2.63 puntos en mujeres y 2.00 en hombres, mientras que el grupo quirúrgico mostró mejoras más pronunciadas. La NOSE también mostró reducciones significativas, especialmente en pacientes sometidos a turbinoplastia y septumplastia combinada. La rinomanometría anterior activa reflejó un aumento en el flujo nasal global en todos los grupos tratados. Tanto los tratamientos médicos como quirúrgicos son efectivos en la mejora de la obstrucción nasal, con mayores beneficios observados en los tratamientos quirúrgicos. Las evaluaciones subjetivas y objetivas son herramientas valiosas y complementarias para la evaluación del tratamiento en pacientes con obstrucción nasal. Estos resultados destacan la importancia de una evaluación integral en el manejo de la obstrucción nasal.
Nasal obstruction is characterized by insufficient airflow and increased resistance in the nasal cavities, affecting patients' quality of life and sleep. This study aims to compare the efficacy of medical and surgical treatment in patients with Nasal obstruction, using subjective evaluations (NOSE and VAS scales) and objective evaluations (active anterior rhinomanometry). This is an experimental and prospective longitudinal study conducted at the Hospital de Clínicas, Paraguay. Forty patients with Nasal obstruction were included, divided into medical treatment (nasal corticosteroids) and surgical treatment (turbinoplasty, septoplasty, or both) groups. Pre- and post-treatment evaluations were performed using the NOSE and VAS scales, and active anterior rhinomanometry. The sample included 52.5% men and 47.5% women, with an average age of 32.18±11.59 years. The main cause of Nasal obstruction was chronic rhinitis (62.5%). Treatments showed significant improvements in subjective and objective evaluations. In the medical group, VAS improved by 2.63 points in women and 2.00 in men, while the surgical group showed more pronounced improvements. The NOSE also showed significant reductions, especially in patients undergoing combined turbinoplasty and septoplasty. Active anterior rhinomanometry reflected an increase in overall nasal flow in all treated groups. Both medical and surgical treatments are effective in improving Nasal obstruction, with greater benefits observed in surgical treatments. Subjective and objective evaluations are valuable and complementary tools for assessing treatment in patients with Nasal obstruction. These results highlight the importance of a comprehensive evaluation in the management of Nasal obstruction.
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Nasal Obstruction/diagnostic imaging , Nasal Cavity/pathology , Nasal Cavity/diagnostic imaging , Paranasal Sinuses/diagnostic imaging , Surgical Procedures, Operative , Magnetic Resonance Imaging/methods , Tomography, X-Ray Computed , Prospective StudiesABSTRACT
Introducción: el cólico nefrítico es una de las causas más frecuentes de consulta en puerta de emergencia. Cuando se presenta en una paciente embarazada, genera un desafío diagnóstico y terapéutico que requiere un abordaje multidisciplinario. Materiales y métodos: se realizó una búsqueda bibliográfica en la base de datos MedLine/PubMed considerando revisiones sistemáticas de literatura, reportes de casos clínicos, estudios observacionales retrospectivos publicados en los últimos 10 años, con el objetivo de obtener sustento informativo para crear un algoritmo diagnóstico y terapéutico que plantee el manejo del cólico nefrítico en la embarazada, dirigido a médicos emergencistas, urólogos y ginecólogos. Resultados: se obtuvieron en total 39 artículos, que fueron analizados, trabajando finalmente en base a 17 textos, que son los citados. Discusión: el diagnóstico se basa en la historia clínica, examen físico, pruebas de laboratorio e imagen. Tratamiento de inicio conservador, que incluye hidratación, analgésicos y antieméticos, reservando la utilización de antibióticos para cuadros infecciosos. De no funcionar éste, se optará por tratamiento intervencionista. Conclusiones: la embarazada con cólico nefrítico se estudia en base a paraclínica humoral y de imagen (ecografía, resonancia nuclear magnética y tomografía axial computada de baja dosis). El tratamiento es principalmente conservador, ante la falla del mismo o ante cuadros infecciosos es quirúrgico.
Introduction: renal colic is one of the most frequent causes of emergency room visits. When it occurs in a pregnant patient, it generates a diagnostic and therapeutic challenge that requires a multidisciplinary approach. Materials and methods: a bibliographic search was carried out in the MedLine/PubMed database considering systematic literature reviews, clinical case reports, retrospective observational studies published in the last 10 years with the aim of obtaining information to create a diagnostic and therapeutic algorithm for the management of nephritic colic in pregnant women, aimed at emergency physicians, urologists and gynecologists. Results: a total of 39 articles were obtained and analyzed, finally working on the basis of 17 texts, which are those cited. Discussion: diagnosis is based on clinical history, physical examination, laboratory and imaging tests. Conservative initial treatment, including hydration, analgesics and antiemetics, reserving the use of antibiotics for infectious conditions. If this does not work, interventional treatment will be chosen. Conclusions: pregnant women with renal colic are studied on the basis of humoral and imaging (ultrasound, magnetic resonance imaging and low dose computed axial tomography). The treatment is mainly conservative; in case of failure or infectious conditions, surgery is performed.
Introdução: a cólica renal é uma das causas mais frequentes de consulta no departamento de emergência. Quando ocorre em uma paciente grávida, gera um desafio diagnóstico e terapêutico que exige uma abordagem multidisciplinar. Materiais e métodos: foi realizada uma pesquisa bibliográfica no banco de dados MedLine/PubMed, considerando revisões sistemáticas da literatura, relatos de casos clínicos, estudos observacionais retrospectivos publicados nos últimos 10 anos, com o objetivo de obter informações para a criação de um algoritmo diagnóstico e terapêutico para o manejo da cólica nefrética em gestantes, destinado a médicos de emergência, urologistas e ginecologistas. Resultados: um total de 39 artigos foi obtido e analisado, sendo que, por fim, trabalhamos com base em 17 textos, que são os citados. Discussão: o diagnóstico é baseado na história clínica, exame físico, exames laboratoriais e de imagem. O tratamento inicial é conservador, incluindo hidratação, analgésicos e antieméticos, reservando o uso de antibióticos para quadros infecciosos. Se isso não funcionar, o tratamento intervencionista será escolhido. Conclusões: as gestantes com cólica renal são estudadas com base em exames humorais e de imagem (ultrassom, ressonância magnética e tomografia axial computadorizada de baixa dose). O tratamento é principalmente conservador, com cirurgia em caso de falha ou condições infecciosas.
Subject(s)
Humans , Female , Pregnancy , Algorithms , Guidelines as Topic , Pregnant Women , Renal Colic , Analgesics , Anti-Bacterial Agents , Antiemetics , Therapeutics , Ultrasonics , Magnetic Resonance Imaging , Tomography , Ultrasonography , Urologists , Gynecologists , Emergency Room VisitsABSTRACT
SUMMARY: Endometriosis, defined as the presence of endometrial glands and stroma outside the uterine cavity, is a chronic inflammatory condition that affects between 8 % and 44 % of women of reproductive age. Occasionally it presents as a sensitive mass in the abdominal wall, in relation to a surgical scar. On the other hand, in the most severe stage of endometriosis, intestinal involvement is common, and endometriotic disease of the appendix may be present even in appendices with macroscopically normal appearance. Simultaneous affectation of both locations is very rare. Nevertheless, treatment of choice is the excision of both lesions with safety margins. The aim of this manuscript was to report a case of simultaneous deep endometriosis affecting the total abdominal wall and vermiform appendix, resected in a single surgical procedure, which subsequently required abdominal wall repair with mesh plasty. Since desmoid tumors and endometriosis share similar clinical signs and unspecific imaging exams, both options should be considered in case of abdominal wall mass in female patients of childbearing age, especially if they have a history of uterine-related surgery.
La endometriosis se define como la presencia de glándulas endometriales y estroma fuera del útero. Es una afección crónica que afecta entre el 8 % y el 44 % de las mujeres en edad reproductiva. Ocasionalmente se presenta como una masa sensible en la pared abdominal, en relación con una cicatriz quirúrgica. Por otro lado, en su estadio más grave de la endometriosis, la afectación intestinal es común y puede afectar al apéndice, pudiendo estar presente incluso en apéndices de apariencia macroscópicamente normal. La afectación de ambas localizaciones simultáneamente es muy infrecuente. Sin embargo, el tratamiento de ambas lesiones es su exéresis quirúrgica con márgenes de seguridad. El objetivo de este manuscrito fue reportar un caso de endometriosis profunda simultánea que afectaba la pared abdominal total y el apéndice vermiforme, las que fueron resecadas en un solo tiempo quirúrgico, incluyendo posteriormente reparación de la pared abdominal con uso de malla. Dado que los tumores desmoides y la endometriosis comparten signos clínicos similares y exámenes de imágenes inespecíficos, se deben considerar ambas opciones en caso de masas en la pared abdominal de mujeres en edad fértil, especialmente si tienen antecedentes de cirugía relacionada con el útero.
Subject(s)
Humans , Female , Adult , Abdominal Wall/surgery , Endometriosis/surgery , Endometriosis/pathology , Appendix/surgery , Appendix/pathology , Surgical Mesh , Magnetic Resonance Imaging , Abdominal Wall/pathology , Endometriosis/diagnostic imagingABSTRACT
SUMMARY: Volume abnormalities in subcortical structures, including the hippocampus, amygdala, thalamus, caudate, putamen, and globus pallidus have been observed in schizophrenia (SZ) and bipolar disorder (BD), not all individuals with these disorders exhibit such changes. In addition, the specific patterns and severity of volume changes may vary between individuals and at different stages of the disease. The study aims to compare the volumes of these subcortical structures between healthy subjects and individuals diagnosed with SZ or BD. Volumetric measurements of lateral ventricle, globus palllidus, caudate, putamen, hippocampus, and amygdale were made by MRI in 52 healthy subjects (HS), 33 patients with SZ, and 46 patients with BD. Automatic segmentation methods were used to analyze the MR images with VolBrain and MRICloud. Hippocampus, amygdala and lateral ventricle increased in schizophrenia and bipolar disorder patients in comparison with control subjects using MRIcloud. Globus pallidus and caudate volume increased in patients with schizophrenia and bipolar disorder compared control subjects using Volbrain. We suggested that our results will contribute in schizophrenia and bipolar disorder patients that assessment of the sub-cortical progression, pathology, and anomalies of subcortical brain compositions. In patients with psychiatric disorders, VolBrain and MRICloud can detect subtle structural differences in the brain.
Se han observado anomalías de volumen en las estructuras subcorticales, incluidos el hipocampo, la amígdala, el tálamo, el núcleo caudado, el putamen y el globo pálido, en la esquizofrenia (SZ) y el trastorno bipolar (BD); no todos los individuos con estos trastornos presentan tales cambios. Además, los patrones específicos y la gravedad de los cambios de volumen pueden variar entre individuos y en diferentes etapas de la enfermedad. El estudio tuvo como objetivo comparar los volúmenes de estas estructuras subcorticales entre sujetos sanos e individuos diagnosticados con SZ o BD. Se realizaron mediciones volumétricas del ventrículo lateral, globo pálido, núcleo caudado, putamen, hipocampo y amígdala mediante resonancia magnética en 52 sujetos sanos (HS), 33 pacientes con SZ y 46 pacientes con BD. Se utilizaron métodos de segmentación automática para analizar las imágenes de resonancia magnética con VolBrain y MRICloud. El hipocampo, la amígdala y el ventrículo lateral aumentaron en pacientes con esquizofrenia y trastorno bipolar en comparación con sujetos de control que utilizaron MRIcloud. El globo pálido y el núcleo caudado aumentaron en pacientes con esquizofrenia y trastorno bipolar en comparación con los sujetos control que utilizaron Volbrain. Sugerimos que en pacientes con esquizofrenia y trastorno bipolar, nuestros resultados contribuirán a la evaluación de la progresión subcortical, la patología y las anomalías de las composiciones cerebrales subcorticales. En pacientes con trastornos psiquiátricos, VolBrain y MRICloud pueden detectar diferencias estructurales sutiles en el cerebro.
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Schizophrenia/diagnostic imaging , Bipolar Disorder/diagnostic imaging , Magnetic Resonance Imaging/methods , Organ Size , Schizophrenia/pathology , Bipolar Disorder/pathology , Cross-Sectional Studies , Retrospective Studies , Cloud ComputingABSTRACT
Introducción: El amniocele es una hernia del saco amniótico a través de un defecto en la pared del útero, el cual puede deberse a ruptura uterina, secundario a daños preexistentes, anomalías uterinas o en un útero sin cicatrices. Caso clínico: Presentamos el caso de una paciente de 37 años, con antecedente de dos partos por cesárea, a quien en la semana 25,5 de embarazo se le diagnostica por ecografía amniocele en la pared anterior de útero contenido por la vejiga, además de signos ecográficos de acretismo placentario. La posterior realización de resonancia magnética confirma el diagnóstico. Se realiza manejo expectante con estancia continua intrahospitalaria estricta. Resolución obstétrica a las 34 semanas por cesárea, con extracción fetal por fondo uterino sin complicaciones, con posterior realización de histerectomía con placenta in situ. Conclusiones: Este reporte de caso ilustra la importancia de la identificación temprana de esta condición por ser una complicación infrecuente, pero de grave pronóstico fetomaterno en ausencia de atención inmediata.
Introduction: Amniocele is a hernia of the amniotic sac through a defect in the uterine wall, which can be caused by uterine rupture secondary to preexisting damage, uterine anomalies, or a scarless uterus. Case report: We present a case of a 37-year-old patient with a history of two previous cesarean deliveries. At 25.5 weeks of gestation, the diagnosis of amniocele in the anterior uterine wall, contained by the bladder, along with ultrasound signs of placenta accreta, was confirmed through ultrasound. Subsequent magnetic resonance imaging further confirmed the diagnosis. Expectant management with strict continuous intrahospital stay was implemented. Obstetric resolution was achieved at 34 weeks through cesarean delivery, with uncomplicated fetal extraction through the uterine fundus. Subsequently, a hysterectomy was performed with the placenta left in situ. Conclusions: This case report illustrates the importance of early identification of this condition due to its infrequent but serious feto-maternal prognosis in the absence of immediate attention.
Subject(s)
Humans , Female , Pregnancy , Adult , Placenta Accreta/diagnostic imaging , Ultrasonography, Prenatal , Placenta Accreta/surgery , Uterine Rupture , Magnetic Resonance Imaging , Cesarean Section , Amnion , Hernia/diagnostic imaging , HysterectomyABSTRACT
Introducción: Las malformaciones del desarrollo cortical se deben a alteraciones en la migración del neuroblasto durante la formación de la corteza cerebral. Se desconoce su frecuencia en embarazos monocoriales. Objetivo: Reportar el caso de un embarazo monocorial con diagnóstico de malformación del desarrollo cortical en uno de los fetos y revisar la literatura referente a su diagnóstico y pronóstico. Método: Mujer de 19 años, embarazo monocorial biamniótico de 26 semanas, que acudió con estudio ecográfico y resonancia fetal que evidenció en uno de los fetos asimetría de los hemisferios cerebrales, hipoplasia de la cisura de Silvio izquierda con simplificación del patrón giral por focos de paquigiria y polimicrogiria, con confirmación posnatal de alteración en la migración neuronal asociada a hipoplasia vermiana. Resultados: Se encontraron en la literatura tres casos de embarazo múltiple monocorial con trastorno de la migración neuronal con recién nacidos vivos. Los hallazgos más comunes fueron microcefalia, lisencefalia e hipoplasia cerebelosa. Conclusiones: El diagnóstico prenatal del trastorno de la migración neuronal se realiza con ecografía y resonancia fetal. La más frecuente es la alteración de la migración neuronal tipo II. El pronóstico depende del tipo de alteración; sin embargo, la mayoría de los casos presentan trastornos epileptiformes con alteraciones del neurodesarrollo.
Introduction: Malformations of cortical development are the result from alterations in the neuroblast migration during the cerebral cortex formation. Its frequency in monochorial multiple pregnancies remains unknown. Objective: To report a case of monochorial multiple pregnancy with diagnosis of malformation of the cortical development in one of the fetuses. In addition, to review the literature regarding the diagnosis and prognosis of this entity. Method: A 19-year-old female with a monochorial diamniotic pregnancy of 26 weeks gestation, arrived with an ultrasound anatomy scan visit, and fetal magnetic resonance imaging, we detected asymmetry in the cerebral hemispheres one of the fetuses, hypoplasia of the left sulcus of Sylvius with simplification of the gyrus pattern due to clusters of pachygyria and polymicrogyria. Those findings were confirmed afterbirth, with a definite diagnosis of neuronal migration disorder associated with vermian hypoplasia. Results: Three cases of monochorial pregnancy with neuronal migration disorder with live newborn, common findings like microcephaly, lissencephaly and vermian hypoplasia. Conclusions: Prenatal diagnosis with neuronal migration disorder is done via ultrasound and magnetic resonance imaging. Neuronal migration disorders type II are the most common of them. Prognosis depends on the type of disorder; however, most patients have epileptiform activity and neurodevelopment impairment.
Subject(s)
Humans , Female , Pregnancy , Young Adult , Malformations of Cortical Development/diagnostic imaging , Pregnancy, Twin , Prenatal Diagnosis , Prognosis , Magnetic Resonance Imaging , Echoencephalography , UltrasonographyABSTRACT
Contexto: A rotura da inserção distal do tendão semimembranoso é uma lesão ocasionada no tendão de um dos músculos do grupo isquiotibiais, acarretando dor no joelho. Para o diagnóstico da lesão do tendão semimembranoso, a ressonância magnética é a principal modalidade de imagem. Descrição do caso: Homem de 63 anos acusa dor no joelho esquerdo há 1 semana. Apresenta melhora da dor com repouso e medicação. Ao exame físico, apresenta teste de Waldron positivo e testes de McMurray e Appley negativos, com edema articular, sem hematomas, apresentando limitação à movimentação devido à dor. A ressonância magnética apresenta a rotura do semimembranoso, e o tratamento foi realizado com medicação analgésica e anti-inflamatória. Discussão: Essa rotura é rara, e surge de uma força em valgo em uma perna hiperextendida externamente. O uso de esteroides anabolizantes pode aumentar o risco de rotura do tendão. Contudo, a ultrassonografia é um método de fácil acesso e é cada vez mais utilizada. O diagnóstico é realizado por meio de ressonância magnética. Seu tratamento pode ser realizado com anti-inflamatórios ou reparo cirúrgico. Conclusão: Relatamos um caso de rotura do tendão semimembranoso, composta por uma sintomatologia como dor no joelho, que pode ser tratada com anti-inflamatório ou reparo cirúrgico.
Subject(s)
Humans , Male , Middle Aged , Rupture , Tendons , Pain , Magnetic Resonance Imaging , Knee JointABSTRACT
The finding of a lipoma in the middle ear is much rarer than its occurrence in the external auditory canal or even the inner ear, with fewer than seven cases described in the literature and none of them in Spain or South America. Despite its benign nature, the location of the lipoma may compromise structures that play a significant role in auditory preservation or balance control, necessitating surgical removal as a curative treatment. The main objective of this article is to describe the presentation of lipomas in the middle ear as a possible, although rare, etiology to consider in patients presenting with hearing loss, instability, or both symptoms concurrently, seeking otorhinolaryngological evaluation.
El hallazgo de un lipoma en el oído medio es mucho más raro que su ocurrencia en el canal auditivo externo o incluso en el oído interno, con menos de siete casos descritos en la literatura y ninguno de ellos en España o Sudamérica. A pesar de su naturaleza benigna, la ubicación del lipoma puede comprometer estructuras que desempeñan un papel significativo en la preservación auditiva o en el control del equilibrio, lo que hace necesaria la extirpación quirúrgica como tratamiento curativo. El objetivo principal de este artículo es describir la presentación de los lipomas en el oído medio como una posible, aunque rara, etiología a considerar en pacientes que presentan pérdida de audición, inestabilidad o ambos síntomas simultáneamente, buscando evaluación otorrinolaringológica.
Subject(s)
Humans , Female , Middle Aged , Ear Neoplasms/diagnostic imaging , Magnetic Resonance Imaging/methods , Lipoma/diagnostic imagingABSTRACT
When examining patients who present both fluctuating auditory symptoms and vestibular symptoms, which can be mistaken for an ear disease, it is important to consider cochlear-carotid fistula as a condition that could generate these clinical manifestations. In this case, additional imaging tests should be performed to demonstrate the lack of continuity at that level and rule out other entities. The objective is to describe the cochleo-carotid dehiscence in a 39-year-old woman and propose it as a possible etiology of a third window syndrome, in order to discuss the relationship between clinical findings, neurotologic examination, and magnetic resonance imaging.
Al examinar a pacientes que presentan síntomas auditivos fluctuantes y síntomas vestibu-lares, que pueden ser confundidos con una enfermedad del oído, es importante considerar la fístula coclear-carotídea como una condición que podría generar estas manifestaciones clínicas. En este caso, se deben realizar pruebas de imagen adicionales para demostrar la falta de continuidad en ese nivel y descartar otras entidades. El objetivo es describir la dehiscencia cocleo-carotídea en una mujer de 39 años y proponerla como una posible etiología del síndrome de la tercera ventana, con el fin de discutir la relación entre los hallazgos clínicos, el examen neurotológico y la resonancia magnética.
Subject(s)
Humans , Female , Adult , Magnetic Resonance Imaging/methods , Carotid Artery, Internal/diagnostic imaging , Cochlea/diagnostic imagingABSTRACT
El síndrome de Brown-Séquard es el conjunto de signos y síntomas causado por hemisección medular de diversos orígenes. Puede generarse por múltiples causas; las traumáticas son las más frecuentes. Las causas menos frecuentes son patología inflamatoria, isquémica, tumoral o infecciosa. Se presenta un niño de 12 años, con instauración aguda y progresiva de un síndrome de hemisección medular derecho, con parálisis hipo/arrefléctica homolateral y afectación de sensibilidad termoalgésica contralateral. En la resonancia magnética de médula espinal, se observó compromiso inflamatorio en hemimédula derecha a nivel de segunda y tercera vértebras torácicas. Con diagnóstico de mielitis transversa idiopática, inició tratamiento con corticoide intravenoso a altas dosis con evolución clínica favorable y restitución de las funciones neurológicas.
Brown-Séquard syndrome refers to a set of signs and symptoms caused by hemisection of the spinal cord from various sources. It may have multiple causes; traumatic injuries are the most frequent ones. The less common causes include inflammation, ischemia, tumors, or infections. This report is about a 12-year-old boy with an acute and progressive course of right hemisection of the spinal cord, with ipsilateral hypo/areflexic paralysis and contralateral loss of thermalgesic sensation. The MRI of the spinal cord showed inflammation in the right side of the spinal cord at the level of the second and third thoracic vertebrae. The patient was diagnosed with idiopathic transverse myelitis and was started on intravenous high-dose corticosteroids; he showed a favorable clinical course and recovered neurological functions.
Subject(s)
Humans , Male , Child , Spinal Cord Injuries/complications , Brown-Sequard Syndrome/diagnosis , Brown-Sequard Syndrome/etiology , Myelitis , Magnetic Resonance Imaging , Inflammation/complicationsABSTRACT
Introducción y objetivo: Demostrar el valor del plano axial del complejo posterior, como apoyo a la detección antenatal de sintelencefalia, variante de holoprosencefalia. Método: Se incluyeron todas las pacientes con diagnóstico de sintelencefalia evaluadas desde el año 2008. En todos los casos se consignaron los datos clínicos, de neurosonografía (NSG), de resonancia magnética (RM) y genética. Resultados: Cuatro casos fueron diagnosticados en el segundo trimestre y en todos se realizó estudio genético y RM. Tres tuvieron en su evolución anomalías extra-SNC y dos de ellos alteraciones cromosómicas, una de ellas incompatible con la vida extrauterina. Lo hallazgos descritos en neuroimagen para esta afección fueron detectados en la NSG, con una excelente correlación con RM, ya fuera esta última realizada en periodo fetal o posnatal. Conclusión: El diagnóstico prenatal de variantes de holoprosencefalia es difícil, considerando la existencia de una fusión medial más acotada que en las formas clásicas. El presente estudio demuestra la utilidad del plano del complejo posterior para la sospecha diagnóstica de sintelencefalia.
Introduction and objective: To demonstrate the value of the axial plane of the posterior complex, as a clue for the antenatal detection of synthelencephaly, a variant of holoprosencephaly. Method: All patients diagnosed with syntelencephaly evaluated since 2008 were included. In all cases, clinical, neurosonography (NSG), magnetic resonance imaging (MRI) and genetic data were recorded. Results: Four cases were diagnosed in the second trimester and in all of them a genetic study and MRI were performed. Three had extra-CNS anomalies in their evolution and two of them chromosomal anomalies, one of them incompatible with extrauterine life. Neuroimaging findings described for this condition were detected by NSG, with an excellent correlation with MRI, whether the latter was performed in the fetal or postnatal period. Conclusion: The prenatal diagnosis of holoprosencephaly variants is difficult, considering the existence of a more limited medial fusion than in the classical forms. The present study demonstrates the usefulness of the posterior complex plane for the diagnostic suspicion of synthelencephaly.
Subject(s)
Humans , Female , Pregnancy , Adult , Young Adult , Magnetic Resonance Imaging , Echoencephalography/methods , Holoprosencephaly/diagnostic imaging , Prenatal Diagnosis , Septum Pellucidum/diagnostic imaging , Retrospective StudiesABSTRACT
INTRODUCTION@#A previous prospective, randomised controlled trial showed that animated videos shown to children before magnetic resonance imaging (MRI) scan reduced the proportion of children needing repeated MRI sequences and improved confidence of the children staying still for at least 30 min. Children preferred the interactive video. We hypothesised that the interactive video is non-inferior to showing two videos (regular and interactive) in improving children's cooperativeness during MRI scans.@*METHODS@#In this Institutional Review Board-approved prospective, randomised, non-inferiority trial, 558 children aged 3-20 years scheduled for elective MRI scan from June 2017 to March 2019 were randomised into the interactive video only group and combined (regular and interactive) videos group. Children were shown the videos before their scan. Repeated MRI sequences, general anaesthesia (GA) requirement and improvement in confidence of staying still for at least 30 min were assessed.@*RESULTS@#In the interactive video group ( n = 277), 86 (31.0%) children needed repeated MRI sequences, two (0.7%) needed GA and the proportion of children who had confidence in staying still for more than 30 min increased by 22.1% after the video. In the combined videos group ( n = 281), 102 (36.3%) children needed repeated MRI sequences, six (2.1%) needed GA and the proportion of children who had confidence in staying still for more than 30 min increased by 23.2% after the videos; the results were not significantly different between the two groups.@*CONCLUSION@#The interactive video group demonstrated non-inferiority to the combined videos group.
Subject(s)
Child , Humans , Child, Preschool , Adolescent , Young Adult , Anesthesia, General , Magnetic Resonance Imaging , Prospective Studies , Simulation Training , Video RecordingABSTRACT
INTRODUCTION@#Ultrasonography (US) is the current standard of care for imaging surveillance in patients at risk of hepatocellular carcinoma (HCC). Magnetic resonance imaging (MRI) has been explored as an alternative, given the higher sensitivity of MRI, although this comes at a higher cost. We performed a cost-effective analysis comparing US and dual-sequence non-contrast-enhanced MRI (NCEMRI) for HCC surveillance in the local setting.@*METHODS@#Cost-effectiveness analysis of no surveillance, US surveillance and NCEMRI surveillance was performed using Markov modelling and microsimulation. At-risk patient cohort was simulated and followed up for 40 years to estimate the patients' disease status, direct medical costs and effectiveness. Quality-adjusted life years (QALYs) and incremental cost-effectiveness ratio were calculated.@*RESULTS@#Exactly 482,000 patients with an average age of 40 years were simulated and followed up for 40 years. The average total costs and QALYs for the three scenarios - no surveillance, US surveillance and NCEMRI surveillance - were SGD 1,193/7.460 QALYs, SGD 8,099/11.195 QALYs and SGD 9,720/11.366 QALYs, respectively.@*CONCLUSION@#Despite NCEMRI having a superior diagnostic accuracy, it is a less cost-effective strategy than US for HCC surveillance in the general at-risk population. Future local cost-effectiveness analyses should include stratifying surveillance methods with a variety of imaging techniques (US, NCEMRI, contrast-enhanced MRI) based on patients' risk profiles.
Subject(s)
Humans , Adult , Carcinoma, Hepatocellular/diagnostic imaging , Liver Neoplasms/diagnostic imaging , Cost-Effectiveness Analysis , Cost-Benefit Analysis , Quality-Adjusted Life Years , Magnetic Resonance Imaging/methodsABSTRACT
BACKGROUND@#Dilated cardiomyopathy (DCM) has a high mortality rate and is the most common indication for heart transplantation. Our study sought to develop a multiparametric nomogram to assess individualized all-cause mortality or heart transplantation (ACM/HTx) risk in DCM patients.@*METHODS@#The present study is a retrospective cohort study. The demographic, clinical, blood test, and cardiac magnetic resonance imaging (CMRI) data of DCM patients in the tertiary center (Fuwai Hospital) were collected. The primary endpoint was ACM/HTx. The least absolute shrinkage and selection operator (LASSO) Cox regression model was applied for variable selection. Multivariable Cox regression was used to develop a nomogram. The concordance index (C-index), area under the receiver operating characteristic curve (AUC), calibration curve, and decision curve analysis (DCA) were used to evaluate the performance of the nomogram.@*RESULTS@#A total of 218 patients were included in the present study. They were randomly divided into a training cohort and a validation cohort. The nomogram was established based on eight variables, including mid-wall late gadolinium enhancement, systolic blood pressure, diastolic blood pressure, left ventricular ejection fraction, left ventricular end-diastolic diameter, left ventricular end-diastolic volume index, free triiodothyronine, and N-terminal pro-B type natriuretic peptide. The AUCs regarding 1-year, 3-year, and 5-year ACM/HTx events were 0.859, 0.831, and 0.840 in the training cohort and 0.770, 0.789, and 0.819 in the validation cohort, respectively. The calibration curve and DCA showed good accuracy and clinical utility of the nomogram.@*CONCLUSIONS@#We established and validated a circulating biomarker- and CMRI-based nomogram that could provide a personalized prediction of ACM/HTx for DCM patients, which might help risk stratification and decision-making in clinical practice.
Subject(s)
Humans , Cardiomyopathy, Dilated/diagnostic imaging , Contrast Media , Nomograms , Retrospective Studies , Stroke Volume , Gadolinium , Ventricular Function, Left , Magnetic Resonance Imaging , Biomarkers , Magnetic Resonance SpectroscopyABSTRACT
BACKGROUND@#To perform anatomical anterior cruciate ligament reconstruction (ACLR), tunnels should be placed relatively higher in the femoral anterior cruciate ligament (ACL) footprint based on the findings of direct and indirect femoral insertion. But the clinical results of higher femoral tunnels (HFT) in double-bundle ACLR (DB-ACLR) remain unclear. The purpose was to investigate the clinical results of HFT and lower femoral tunnels (LFT) in DB-ACLR.@*METHODS@#From September 2014 to February 2016, 83 patients who underwent DB-ACLR and met the inclusion and exclusion criteria were divided into HFT-ACLR (group 1, n = 37) and LFT-ACLR (group 2, n = 46) according to the position of femoral tunnels. Preoperatively and at the final follow-up, clinical scores were evaluated with International Knee Documentation Committee (IKDC), Tegner activity, and Lysholm score. The stability of the knee was evaluated with KT-2000, Lachman test, and pivot-shift test. Cartilage degeneration grades of the International Cartilage Repair Society (ICRS) were evaluated on magnetic resonance imaging (MRI). Graft tension, continuity, and synovialization were evaluated by second-look arthroscopy. Return-to-sports was assessed at the final follow-up.@*RESULTS@#Significantly better improvement were found for KT-2000, Lachman test, and pivot-shift test postoperatively in group 1 ( P >0.05). Posterolateral bundles (PL) showed significantly better results in second-look arthroscopy regarding graft tension, continuity, and synovialization ( P <0.05), but not in anteromedial bundles in group 1. At the final follow-up, cartilage worsening was observed in groups 1 and 2, but it did not reach a stastistically significant difference ( P >0.05). No statistically significant differences were found in IKDC subjective score, Tegner activity, and Lysholm score between the two groups. Higher return-to-sports rate was found in group 1 with 86.8% (32/37) vs. 65.2% (30/46) in group 2 ( P = 0.027).@*CONCLUSION@#The HFT-ACLR group showed better stability results, better PL, and higher return-to-sports rate compared to the LFT-ACLR group.
Subject(s)
Humans , Follow-Up Studies , Anterior Cruciate Ligament/surgery , Knee Joint/surgery , Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Reconstruction/methods , Magnetic Resonance Imaging , Treatment OutcomeABSTRACT
In this study, we investigated how empathic neural responses unfold over time in different empathy networks when viewing same-race and other-race individuals in dynamic painful conditions. We recorded magnetoencephalography signals from Chinese adults when viewing video clips showing a dynamic painful (or non-painful) stimulation to Asian and White models' faces to trigger painful (or neutral) expressions. We found that perceived dynamic pain in Asian models modulated neural activities in the visual cortex at 100 ms-200 ms, in the orbitofrontal and subgenual anterior cingulate cortices at 150 ms-200 ms, in the anterior cingulate cortex around 250 ms-350 ms, and in the temporoparietal junction and middle temporal gyrus around 600 ms after video onset. Perceived dynamic pain in White models modulated activities in the visual, anterior cingulate, and primary sensory cortices after 500 ms. Our findings unraveled earlier dynamic activities in multiple neural circuits in response to same-race (vs other-race) individuals in dynamic painful situations.
Subject(s)
Adult , Humans , Brain Mapping , Pain , Empathy , Racism , Gyrus Cinguli/physiology , Magnetic Resonance Imaging , Brain/physiologyABSTRACT
The organization of the brain follows a topological hierarchy that changes dynamically during development. However, it remains unknown whether and how cognitive training administered over multiple years during development can modify this hierarchical topology. By measuring the brain and behavior of school children who had carried out abacus-based mental calculation (AMC) training for five years (starting from 7 years to 12 years old) in pre-training and post-training, we revealed the reshaping effect of long-term AMC intervention during development on the brain hierarchical topology. We observed the development-induced emergence of the default network, AMC training-promoted shifting, and regional changes in cortical gradients. Moreover, the training-induced gradient changes were located in visual and somatomotor areas in association with the visuospatial/motor-imagery strategy. We found that gradient-based features can predict the math ability within groups. Our findings provide novel insights into the dynamic nature of network recruitment impacted by long-term cognitive training during development.