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1.
J. Health Biol. Sci. (Online) ; 10(1): 1-8, 01/jan./2022. tab, graf, ilus
Article in Portuguese | LILACS | ID: biblio-1378478

ABSTRACT

Objetivos: descrever os aspectos epidemiológicos, espaciais e temporais da leishmaniose visceral humana, no município de Sobral, no período de 2007 a 2019. Métodos: foi realizado um estudo epidemiológico descritivo e ecológico de análise espacial e temporal, com uso dos programas Quantum-Gis e Joinpoint. Resultados: foram confirmados 316 casos novos, predominantemente, no sexo masculino, nas faixas etárias de 1 a 4 anos (26,3%) e de 20 a 39 anos (24,0%), na zona urbana. Febre (95,9%), fraqueza (85,1%), emagrecimento (80,1%), palidez (73,7%), esplenomegalia (75,6%) e hepatomegalia (69,3%) foram os sinais clínicos mais frequentes. A doença se concentrou em quatro bairros: Terrenos Novos, Centro, Expectativa e Sinhá Saboia, expressando áreas mais densas (quentes). A incidência e a letalidade foram crescentes no início do período e decrescentes no final, com uma inversão destes indicadores no ano de 2014. Conclusão: em Sobral, a leishmaniose visceral humana é um agravo considerado relevante para o serviço de vigilância em saúde com necessidade de intensificação das ações de controle entomológico, zoonótico e de manejo ambiental, principalmente nas áreas mais densas.


Objectives: the objective was to describe the epidemiological, spatial, and temporal aspects of human visceral leishmaniasis, in the municipality of Sobral, from 2007 to 2019. Methods: A descriptive, spatial and temporal ecological study was carried out using Quantum-Gis and Joinpoint programs. Results: 316 new cases were confirmed, predominantly in males, in the age groups of 1 to 4 years (26.3%) and 20 to 39 years (24.0%), mainly in the urban area. Fever (95.9%), weakness (85.1%), weight loss (80.1%), pallor (73.7%), splenomegaly (75.6%), and hepatomegaly (69.3%) were the most frequent clinical signs. The disease was concentrated in four neighborhoods (Terrenos Novos, Centro, Expectativa, and Sinhá Saboia), hot spots. The incidence and case-fatality increased at the beginning of the period but decreased at the end, with an inversion in these in the year 2014. Conclusion: In Sobral, human visceral leishmaniasis is a disease considered relevant to the health surveillance service, with the need to intensify entomological, zoonotic, and environmental management actions, especially in denser areas.


Subject(s)
Leishmaniasis, Visceral , Signs and Symptoms , Health Surveillance , Epidemiology , Mortality , Indicators and Reagents , Age Groups
2.
Oncología (Ecuador) ; 32(2): 129-140, 2 de Agosto del 2022.
Article in Spanish | LILACS | ID: biblio-1391883

ABSTRACT

In troducción:La mortalidad de los pacientes con cáncer,ingresados en unaunidad de terapia intensiva puede ser estimada usando las escalas de sepsis. El objetivo del presente estudio fue realizar una prueba diagnóstica entre las principales escalas en un grupo de pacientes oncológicos de un centro de referencia de Guayaquil-Ecuador.Met odología: Se realizó un estudio transversal, en la unidad de terapia intensiva del Instituto Oncológico Nacional "Dr Juan Tanca Marengo" de SOLCA-Guayaquil, en el período octubre 2019a noviembre del 2020. La muestrafue probabilística, de pacientes con diagnóstico oncológicos clínicos ingresado en UCI. Se registró edad, tipo de cáncer, antecedentes familiares, mortalidad y las escalas SOFA y APACHE II. Se utiliza estadística descriptiva, se realiza una prueba diagnóstica y un análisis de supervivencia.R esultados: Se analizan 99 casos, de 57 ± 16 añosde edad, 37 hombres (37.4%). Con Hipertensión arte-rial (39.4%) y diabetes mellitus tipo 2 (17.1%). 12.1 %casos de linfoma no Hodgkiny cáncer intestinal 11.1%; 17 fallecimientos (17.2%). La puntuación global SOFA fue de 6.8 ± 3.0. La puntuación global APACHE II de 18.6 ± 7.0. El riesgo de mortalidad fue estadísticamente significativo a partir del 5to día. La puntuación SOFA >6 tuvo una sensibilidad del 88.24 %, valor predictivo (VP) positivo fue muy bajo, así como la especificidad; el VP negativo fue de 97%. La escala APACHE II, tuvo una sensibilidad del 94.12 %, con una especificidad de 96.34 %; VP positivo, comparada a la escala SOFA fue el doble.Co nclusión: La escala APACHE II en pacientes oncológicos clínicos ingresados en UCI predice de la ma-nera más exacta la mortalidad cuando la puntuación es mayor a 18


Subject(s)
Neoplasms , Survival Analysis , Mortality , Hospital Mortality , Critical Care , Neoplasm Metastasis
3.
Oncología (Ecuador) ; 32(2): 141-156, 2 de Agosto del 2022.
Article in Spanish | LILACS | ID: biblio-1391889

ABSTRACT

Introducción: El Linfoma de Hodgkin (LH), es una neoplasia hematológica poco frecuente, donde las células neoplásicas forman una minoría del tumor y están rodeados por un medio inflamatorio reactivo que incluye linfocitos, eosinófilos, neutrófilos, histiocitos y células plasmáticas. El objetivo del presente estudio fue describir una población con esta patología y su supervivencia en 7 años de seguimiento. Metodología Este estudio longitudinal, se realizó en el Hospital Carlos Andrade Marín, de Quito, Ecuador, del período 2013-2019, con una muestra no probabilística, de pacientes con LH. Se registraron variables demográficas, clínicas, de laboratorio, clasificación Ann Arbor, clasificación histológica, tratamiento y respuesta, mortalidad y tiempo de supervivencia. Se utiliza estadística descriptiva; bivariado y un análisis de supervivencia. Resultados: Se analizan 73 casos, 43 hombres (58.9 %). El grupo de 61 a 70 años fue el más prevalente con 19 casos (26%). 1 caso (4.1 %) con VIH, 7 casos (9.6%) con inmunosupresores. Síntomas B en 49 casos (67.1%). Adenomegalias en 15 casos (20.5 %). Masa Bulky 5 casos (6.8 %). Fallecieron 22 casos (30.1 %). Supervivencia de 52.8 meses, el 83.6% de recibieron Adriamicina, Bleomicina, Vincristina y Dacarbazina como 1ra línea de tratamiento, con remisión completa en el 61.7%. El estadio IV de Ann Arbor con Hazard Ratio (HR): 3.47,(IC95%: 1.20 ­6.11, P= 0.04), depleción linfocitaria HR: 4.98 (IC95%: 1.31 ­9.47, P= 0.04).Hemoglobina < 10.5 g/dL HR: 2.40,(IC95%: 1.47­5.94, P= 0.03), Albúmina < 4 g/dL HR: 4.02, IC95%: 1.94­7.26, P= 0.01) y linfocitos < 600 células/µL HR: 4.57, (IC95%: 1.85 ­11.28, P= 0.001)Conclusión: La prevalencia de LH fue ligeramente mayor en hombres, con una relación de 1.1: 1. LA incidencia fue bimodal, entre 31-40 años y entre 61-70 años, con síntomas B y adenomegalias. Los estadios II y III (Ann Arbor) fueron los más frecuentes. La Hemoglobina y albúmina fue menor en los fallecidos. El tratamiento de primera línea tuvo remisión completa en el 61.7% de los casos. La ausencia de síntomas B, se relacionó con una mayor supervivencia; los estadios avanzados se relacionaron con peor supervivencia; la supervivencia fue mayor en pacientes que obtuvieron remisión completa con la primera línea de tratamiento; la supervivencia general fue menor a la encontrada en países desarrollados


In troduction: Hodgkin's Lymphoma (HL) is a rare hematological neoplasm where neoplastic cells form a minority of the tumor and are surrounded by a reactive inflammatory medium that includes lympho-cytes eosinophils, neutrophils, histiocytes, and plasma cells. The objective of the present study was to describe a population with this pathology and its survival in 7 years of follow-up.Met hodology: This longitudinal study was carried out at the Carlos Andrade Marín Hospital, in Quito, Ec-uador, from 2013-2019, with a non-probabilistic sample of patients with HL. Demographic, clinical, labor-atory variables, Ann Arbor classification, histological classification, treatment and response, mortality, and survival time were recorded. Descriptive statistics are used; bivariate and survival analysis.R esults: 73 cases were analyzed, 43 men (58.9%). The group of 61 to 70 years was the most prevalent, with 19 cases (26%). 1 case (4.1%) with AIDS and 7 cases (9.6%) with immunosuppressants. B symp-toms in 49 cases (67.1%). Enlarged lymph nodes in 15 cases (20.5%). Bulky mass 5 cases (6.8%). 22 cases died (30.1%). Survival of 52.8 months, 83.6% received Adriamycin, Bleomycin, Vincristine, and Dacarbazine as1st line of treatment, with complete remission in 61.7%. Ann Arbor stage IV with Hazard Ratio (HR): 3.47, (95% CI: 1.20 ­6.11, P= 0.04), lymphocyte depletion HR: 4.98 (95% CI: 1.31 ­9.47, P= 0.04). Hemoglobin < 10.5 g/dL HR: 2.40, (95% CI: 1.47 ­5.94, P= 0.03), Albumin < 4 g/dL HR: 4.02, 95% CI: 1.94 ­7.26, P= 0.01) and lymphocytes < 600 cells/ µL HR: 4.57, (95% CI: 1.85 ­11.28, P= 0.001).C o nclusion: The prevalence of HL was slightly higher in men, with a ratio of 1.1: 1. The incidence was bimodal, between 31-40 years and between 61-70 years, with B symptoms and enlarged lymph nodes. Stages II and III (Ann Arbor) were the most frequent. Hemoglobin and albumin were lower in the de-ceased. First-line treatment had complete remission in 61.7% of cases. The absence of B symptoms was related to more remarkable survival; advanced stages were related to worse survival; survival was higher in patients who achieved complete remission with the first line of treatment; overall survival was lower than that found indeveloped countries


Subject(s)
Hodgkin Disease , Survival Analysis , Mortality , Lymphoma, AIDS-Related , Hospital Mortality
4.
Medicina UPB ; 41(2): 100-106, julio-diciembre 2022. tab
Article in Spanish | LILACS, COLNAL | ID: biblio-1392112

ABSTRACT

Objetivo: el virus SARS-COV-2 llegó a Medellín el 9 de marzo del 2020, afectando hasta el 8 de octubre 2021 a 397.395 personas en esta ciudad. Este estudio busca describir el comportamiento clínico de los pacientes hospitalizados en la Clínica SOMA en el periodo entre julio 1 de 2020 y enero 31 de 2021, así como identificar variables clínicas y paraclínicas asociadas a su ingreso a UCI y la mortalidad. Metodología: cohorte retrospectiva con datos de historias clínicas de adultos admitidos en la Clínica SOMA por Covid-19 entre julio 1 de 2020 y enero 31 de 2021. Resultados: se identificaron 849 individuos adultos con Covid-19, de los cuales 326 fueron hospitalizados (38.4%), la mortalidad fue del 13%. Los factores más asociados a severidad fueron la disnea, hipertensión arterial, enfermedad cardiovascular, dímero D elevado, deshidrogenasa láctica, linfopenia y una mayor edad. Conclusiones: nuestro estudio evidenció un comportamiento similar al descrito en otros estudios en el mundo frente a variables al ingreso por Covid-19, que se asocian con peores desenlaces clínicos.


Objective: SARS COV-2 virus arrived in Medellin on March 9, 2020, affecting 397 395 people in Medellin by Oct 8, 2021. This study aims to describe the clinical behavior of patients hospitalized in SOMA Clinic between July 1st, 2020, and January 31st, 2021, and to identify clinical and paraclinical variables associated with ICU entry and mortality. Methodology: retrospective cohort with data from medical records of all patients over 18 years of age admitted to the SOMA Clinic for Covid-19 between July 1st, 2020, and January 31st, 2021. Results: 849 patients with Covid-19 consulted the emergency room of the SOMA Clinic, out of which 326 were hospitalized (38.4%) with a mortality of 13%. Dyspnea, hypertension, cardiovascular disease, elevated D-dimer values, lactic dehydrogenase, and lymphopenia and older age were associated with severity. Conclusions: like other studies worldwide, we evidenced clinical and paraclinical parameters at entry that are associated with worst clinical outcomes in a SARS-COV-2 infection.


Objetivo: o vírus SARS-COV-2 chegou a Medellín em 9 de março de 2020, afetando 397.395 pessoas nesta cidade até 8 de outubro de 2021. Este estudo busca descrever o comportamento clínico dos pacientes internados na Clínica SOMA no período entre 1º de julho de 2020 e 31 de janeiro de 2021, bem como identificar variáveis clínicas e paraclínicas associadas à sua admissão na UTI e mortalidade. Metodologia: coorte retrospectiva com dados de prontuários de adultos internados na Clínica SOMA por Covid-19 entre 1º de julho de 2020 e 31 de janeiro de 2021.Resultados: foram identificados 849 indivíduos adultos com Covid-19, dos quais 326 foram hospitalizados (38,4%), a mortalidade foi de 13%. Os fatores mais associados à gravidade foram dispneia, hipertensão arterial, doença cardiovascular, D-dímero elevado, desidrogenase lática, linfopenia e idade avançada. Conclusões: nosso estudo mostrou um comportamento semelhante ao descrito em outros estudos no mundo frente às variáveis na admissão por Covid-19, que estão associadas a piores desfechos clínicos.


Subject(s)
Humans , COVID-19 , Viruses , Mortality , Emergency Service, Hospital , Infections , Intensive Care Units , Lymphopenia
5.
Nursing (Säo Paulo) ; 25(291): 8430-8447, ago.2022.
Article in English, Portuguese | LILACS, BDENF | ID: biblio-1392129

ABSTRACT

Objetivo: mapear o conhecimento na literatura científica acerca dos efeitos da pandemia da covid-19 na hospitalização e mortalidade, em pacientes adultos, por doenças crônicas transmissíveis. Método: revisão de escopo, realizada em janeiro de 2022, nas seguintes bases de dados: CINAHL, Embase, LILACS, MEDLINE, e Web of Science. Os descritores utilizados na busca foram: Doenças Transmissíveis, Hospitalização, Mortalidade e COVID-19. O processo de seleção foi feito por dois revisores independentes por meio da plataforma Rayyan®. Resultados: foram incluídos 36 estudos, dos quais geraram-se as categorias: Internações e mortalidade relacionadas à covid-19 e às doenças crônicas transmissíveis; possíveis causas de agravamento dos pacientes com a covid-19 e doenças crônicas transmissíveis; e Controle das doenças crônicas transmissíveis no contexto da pandemia. Conclusão: observou-se que as hospitalizações e as mortes pelas doenças crônicas transmissíveis estiveram associadas à coinfecção com a covid-19, apesar de fatores sociodemográficos e epidemiológicos também interferirem na ocorrência.(AU)


Objective: to map the knowledge in the scientific literature about the effects of the covid-19 pandemic on hospitalization and mortality, in adult patients, due to chronic communicable diseases. Method: scoping review, carried out in January 2022, in the following databases: CINAHL, Embase, LILACS, MEDLINE, and Web of Science. The descriptors used in the search were: Communicable Diseases, Hospitalization, Mortality and COVID-19. The selection process was carried out by two independent reviewers through the Rayyan® platform. Results: 36 studies were included, from which the following categories were generated: Hospitalizations and mortality related to covid-19 and chronic communicable diseases; Possible causes of worsening of patients with covid-19 and chronic communicable diseases; and Control of chronic communicable diseases in the context of the pandemic. Conclusion: it was observed that hospitalizations and deaths from chronic communicable diseases were associated with coinfection with covid-19, although sociodemographic and epidemiological factors also interfere in the occurrence.(AU)


Objetivo: mapear el conocimiento en la literatura científica sobre los efectos de la pandemia de covid-19 en la hospitalización y mortalidad, en pacientes adultos, por enfermedades crónicas transmisibles. Método: revisión de alcance, realizada en enero de 2022, en las siguientes bases de datos: CINAHL, Embase, LILACS, MEDLINE y Web of Science. Los descriptores utilizados en la búsqueda fueron: Enfermedades Transmisibles, Hospitalización, Mortalidad y COVID-19. El proceso de selección fue realizado por dos revisores independientes a través de la plataforma Rayyan®. Resultados: se incluyeron 36 estudios, a partir de los cuales se generaron las siguientes categorías: Hospitalizaciones y mortalidad relacionadas con covid-19 y enfermedades crónicas transmisibles; Posibles causas de empeoramiento de pacientes con covid-19 y enfermedades crónicas transmisibles; y Control de enfermedades crónicas transmisibles en el contexto de la pandemia. Conclusión: se observó que las hospitalizaciones y muertes por enfermedades crónicas transmisibles se asociaron con la coinfección por covid-19, aunque factores sociodemográficos y epidemiológicos también interfieren en la ocurrencia.(AU)


Subject(s)
Communicable Diseases , Mortality , COVID-19 , Hospitalization
6.
RECIIS (Online) ; 16(2): 221-226, abr.-jun. 2022. graf
Article in Portuguese | LILACS | ID: biblio-1378340

ABSTRACT

A dinâmica da pandemia de covid-19 vem evoluindo segundo fases marcadas por uma maior ou menor taxa de infecção, e diferentes impactos sobre o sistema de saúde e a mortalidade. Essas fases foram estudadas segundo quatro indicadores disponibilizados no sistema MonitoraCovid-19: positividade de testes de diagnóstico, número de casos, número de óbitos e o número de pessoas com ao menos duas doses de vacinas ­ padronizados numa série histórica para permitir sua comparação. São distinguidas cinco fases, marcadas pela circulação de diferentes variantes do vírus, estratégias de implementação ­ ou mesmo boicote ­ de medidas de controle e a vacinação gradativa da população. Esses indicadores podem ser usados no futuro para monitorar tendências e apontar políticas públicas adequadas.


The dynamics of the covid-19 pandemic has evolved according to phases marked by a higher or lower rate of infection, the different impacts on the health system and mortality. These phases were studied according to four indicators made available by the MonitoraCovid-19 system: positivity rates of diagnostic tests, number of cases, number of deaths and number of people who received at least two vaccine doses, standardized in a historical series to allow their comparison. Five phases are discerned, evidenced by the circulation of different virus variants, strategies employed to implement -or even undermine ­ disease control measures and the gradual vaccination of the population. These indicators can be used in the future to monitor trends and point out appropriate public policies.


La dinámica de la pandemia de covid-19 ha evolucionado según fases marcadas por una mayor o menor tasa de contagios, sus diferentes impactos en el sistema de salud y mortalidad. Estas fases se estudiaron según cuatro indicadores disponibles en el sistema MonitoraCovid-19: positividad de las pruebas diagnósticas, número de casos, número de defunciones y el número de personas vacunadas con al menos dos dosis, estandarizados en una serie histórica para permitir su comparación. Se distinguen cuatro fases, marcadas por la circulación de diferentes variantes del virus, las estrategias de implementación - o mismo el boicoteode medidas de control y la paulatina vacunación de la población. Estos indicadores pueden utilizarse en el futuro para monitorear tendencias y señalar políticas públicas apropiadas.


Subject(s)
Humans , Pandemics , COVID-19 , Health Policy , Indicators and Reagents , Brazil , Mass Vaccination , Mortality , Diagnostic Techniques and Procedures
7.
Rev. colomb. cir ; 37(3): 393-400, junio 14, 2022. tab
Article in Spanish | LILACS | ID: biblio-1378693

ABSTRACT

Introducción. El trauma cervical penetrante es una entidad poco frecuente, con tendencia al alza, de considerable morbimortalidad. Es fundamental conocer su manejo por cirujanos en entrenamiento, quienes en su mayoría son comúnmente los proveedores del tratamiento en las áreas de urgencias. El objetivo de este estudio fue demostrar la experiencia de un centro de trauma en México en el tratamiento de trauma cervical penetrante administrado por cirujanos en entrenamiento. Métodos. Estudio retrospectivo de pacientes con diagnóstico de trauma cervical penetrante sometidos a exploración cervical entre los años 2014 y 2019. Se identificaron 110 expedientes, se excluyeron 26 por falta de datos indispensables para la investigación y se analizaron los datos de 84 pacientes. Resultados. El 96,4 % de los pacientes fueron hombres, la mayoría entre 16 y 50 años (83,3 %) y la zona anatómica II fue la más comúnmente lesionada (65,4 %). Las etiologías más frecuentes fueron heridas por arma cortopunzante (67,9 %) y heridas por proyectil de arma de fuego (25 %). El 95 % de los procedimientos fueron realizados por residentes de cuarto y quinto año. La mediana de días de estancia hospitalaria fue de 2 días. La incidencia de complicaciones fue de 9,5 % y la mortalidad de 1,2 %. Conclusiones. Los cirujanos generales en etapa de formación entrenados en centros de trauma tienen la capacidad de tratar de forma óptima el trauma cervical penetrante sin modificación de las tasas de morbimortalidad descritas en la literatura internacional.


Introduction. Penetrating cervical trauma is a rare entity, with an upward trend, of considerable morbidity and mortality. It is essential to acknowledge its management by surgeons in training, who are usually the providers in the emergency areas. The objective of this study was to demonstrate the experience of a trauma center in Mexico in the treatment of penetrating cervical trauma by surgeons in training. Methods. This was a retrospective study of patients diagnosed with penetrating cervical trauma who underwent cervical examination between 2014 and 2019; 110 records were identified, 26 were excluded due to lack of essential data for the analysis, and the data of 84 patients were included. Results. 96.4% of the patients were men, the majority between 16 and 50 years old (83.3%) and the anatomic zone II was the most frequently injured (65.4%). The most common etiologies were stab wounds (67.9%) and gunshot wounds (25%). Ninety five percent of the procedures were performed by fourth- and fifth-year residents. The median number of days of hospital stay was 2 (2-4) days. The incidence of complications was 9.5% and mortality in 1.2%. Conclusions. General surgeons in the trauma training stage can optimally treat penetrating cervical trauma with the same morbidity and mortality rates described in the international literature.


Subject(s)
Humans , General Surgery , Trauma Centers , Wounds and Injuries , Surgical Procedures, Operative , Mortality , Education, Medical, Graduate , Neck
8.
Rev. colomb. cir ; 37(3): 401-407, junio 14, 2022. tab, fig
Article in Spanish | LILACS | ID: biblio-1378694

ABSTRACT

Introducción. A nivel mundial los tumores gastrointestinales tienen un impacto importante en la mortalidad y se asocian a diferentes factores, entre ellos regionales y sociodemográficos. El objetivo de este estudio fue describir la variación en el tiempo del cáncer gastrointestinal en una población del centro occidente de Colombia, dada su alta incidencia y desenlace frecuentemente fatal.Métodos. Se realizó un estudio retrospectivo observacional con muestreo no probabilístico en un tiempo de seis años. Se seleccionaron pacientes diagnosticados con algún tipo de neoplasia del tracto digestivo, en un hospital de tercer nivel del centro occidente de Colombia. Resultados. Se evaluaron un total de 1152 pacientes. Los tumores del tracto digestivo superior (esófago, unión esófago-gástrica y estómago) fueron los más frecuentes (44 %), seguidos de los tumores del tracto digestivo medio e inferior (intestino delgado, colon, recto y ano; 31 %) y de los tumores hepato-bilio-pancreáticos (25 %). La edad media de presentación fue 64,6 años, con una mayor frecuencia en el sexo masculino (51,6 %). El adenocarcinoma fue el tipo histológico más común.Conclusión. Los resultados de este estudio muestran que los tumores gastrointestinales son una neoplasia frecuente en nuestro país, siendo los tumores gástricos los que se presentan con mayor prevalencia, seguidos de los tumores colorrectales y las neoplasias biliopancreáticas, las cuales se mantiene en el tiempo.


Introduction. Worldwide, gastrointestinal tumors have a significant impact on mortality and are associated with different factors, including regional and sociodemographics. The objective of this study was to describe the variation over time of gastrointestinal cancer in a population from Central-Western Colombia, given its high incidence and frequently fatal outcome. Methods. An observational retrospective study with non-probabilistic sampling was carried out over a period of six years. Patients diagnosed with some type of neoplasm of the digestive tract were selected in a tertiary care hospital in the Central-Western Colombia. Results. A total of 1152 patients were evaluated. Tumors of the upper digestive tract (esophagus, esophagogastric junction, and stomach) were the most frequent (44%), followed by tumors of the middle and lower digestive tract (small intestine, colon, rectum and anus; 31%), and hepatobiliary-pancreatic tumors (25%). The mean age of presentation was 64.6 years with a higher frequency in males (51.6%). Adenocarcinoma was the most common histological type.Conclusion. The results of this study show that gastrointestinal tumors are a frequent neoplasm in our country, with gastric tumors being the most prevalent, followed by colorectal tumors and biliopancreatic neoplasms, which are maintained over time.


Subject(s)
Humans , Mortality , Gastrointestinal Neoplasms , Stomach , Incidence , Colon , Neoplasms
9.
Rev. colomb. cir ; 37(3): 417-427, junio 14, 2022. fig, tab
Article in Spanish | LILACS | ID: biblio-1378696

ABSTRACT

Introducción. El hígado continúa siendo uno de los órganos más afectados en los pacientes con trauma. Su evaluación y manejo han cambiado sustancialmente con los avances tecnológicos en cuanto a diagnóstico y las técnicas de manejo menos invasivas. El objetivo de este estudio fue realizar un análisis de los resultados del manejo no operatorio del trauma hepático en cuanto a incidencia, eficacia, morbimortalidad, necesidad de intervención quirúrgica, tasa y factores relacionados con el fallo del manejo no operatorio. Métodos. Se realizó un estudio descriptivo observacional retrospectivo, analizando pacientes con trauma hepático confirmado con tomografía o cirugía, durante un periodo de 72 meses, en el Hospital Universitario San Vicente Fundación, un centro de IV nivel de atención, en Medellín, Colombia. Resultados. Se incluyeron 341 pacientes con trauma hepático, 224 por trauma penetrante y 117 por trauma cerrado. En trauma penetrante, 208 pacientes fueron llevados a cirugía inmediatamente, el resto fueron manejados de manera no operatoria, con una falla en el manejo en 20 pacientes. En trauma cerrado, 22 fueron llevados a cirugía inmediata y 95 sometidos a manejo no operatorio, con una falla en 9 pacientes. La mortalidad global fue de 9,7 % y la mortalidad relacionada al trauma hepático fue de 4,4 %. El grado del trauma, el índice de severidad del trauma y las lesiones abdominales no hepáticas no se consideraron factores de riesgo para la falla del manejo no operatorio. Conclusiones. El manejo no operatorio continúa siendo una alternativa segura y efectiva para pacientes con trauma hepático, sobretodo en trauma cerrado. En trauma penetrante se debe realizar una adecuada selección de los pacientes.


Introduction. The liver continues to be one of the most affected organs in trauma patients. Its evaluation and management have changed substantially with technological advances in diagnosis and less invasive techniques. The objective of this study was to perform an analysis of the results of non-operative management of liver trauma in terms of incidence, efficacy, morbidity and mortality, need for surgical intervention, rate and factors related to the failure of non-operative management.Methods. A retrospective observational descriptive study was performed, analyzing patients with hepatic trauma confirmed by tomography or surgery, during a period of 72 months at the Hospital Universitario San Vicente Fundación level 4 medical center, in Medellín, Colombia.Results. 341 patients with liver trauma were analyzed, 224 with penetrating trauma and 117 with blunt trauma. In the penetrating trauma group, 208 patients were taken to surgery immediately, the rest were managed nonoperatively with a failure in 20 patients. In the blunt trauma group, 22 were taken to immediate surgery and 95 underwent nonoperative management, with failure in nine patients. Overall mortality was 9.7% and mortality related to liver trauma was 4.4%. Trauma grade, trauma severity index, and non-hepatic abdominal injuries were not considered risk factors for failure of nonoperative managementConclusions. Nonoperative management continues to be a safe and effective alternative for patients with liver trauma, especially in blunt trauma. In penetrating trauma, an adequate selection of patients must be made.


Subject(s)
Humans , Surgical Procedures, Operative , Mortality , Liver , Wounds and Injuries , Head Injuries, Closed , Conservative Treatment
10.
Rev. colomb. cir ; 37(3): 434-447, junio 14, 2022. tab
Article in Spanish | LILACS | ID: biblio-1378718

ABSTRACT

Introducción. En las últimas décadas, la terapia endovascular en aneurismas aórticos abdominales ha ganado un papel representativo en los escenarios quirúrgicos, lo que nos motivó a conocer los resultados de este procedimiento en nuestra población. Métodos. Estudio analítico retrospectivo en el cual se incluyeron los primeros 50 casos de aneurismas aórticos abdominales con terapia endovascular, en la ciudad de Manizales, Colombia, entre los años 2015 y 2021. Se describió la población estudiada, la relación de los antecedentes prequirúrgicos con las complicaciones posoperatorias, la estancia hospitalaria y la mortalidad. Resultados.La edad promedio fue de 73 años, el sexo predominante fue el femenino (72 %), el aneurisma fusiforme fue el tipo más frecuente (63,3 %), con un diámetro promedio de 70 mm (+/- 17,3 mm). En relación con los antecedentes, el más frecuente fue hipertensión arterial (86 %), encontrándose una asociación entre la presencia de enfermedad pulmonar obstructiva crónica e hipertensión arterial con las complicaciones. Se encontró también relación entre el valor de creatinina con las complicaciones. Las complicaciones tempranas fueron de carácter leve en la mayoría de los casos (30,6 %), a diferencia de las tardías, que fueron principalmente graves (12,5 %), asociadas a una mortalidad del 10,2 % y una estancia hospitalaria promedio de 10,8 días (mediana de 5 días). Conclusiones. La población analizada tiene una alta carga de morbilidad, en la cual factores como los antecedentes médicos prequirúrgicos y la función renal, se asocian con una mayor morbilidad postquirúrgica y mortalidad.


Introduction. In recent decades, endovascular therapy in abdominal aortic aneurysms has gained a representative role in surgical scenarios, which motivated us to learn about the results of this procedure in our population. Methods. Retrospective analytical study, which included the first 50 cases of abdominal aortic aneurysms with endovascular therapy, in the city of Manizales, Colombia, between 2015 and 2021. The study population was described as the relationship between pre-surgical history and post-operative complications, hospital stay and mortality. Results. The average age was 73 years, the predominant sex was female (72%), the fusiform aneurysm was the most frequent type (63.3%), with an average diameter of 70 mm (± 17.3 mm). In relation to history, the most frequent was arterial hypertension (86%), finding an association between the presence of chronic obstructive pulmonary disease and arterial hypertension with complications. A relationship was also found between the creatinine value and complications. Early complications were mild in most cases (30.6%), unlike late complications, which were mainly serious (12.5%), associated with a mortality of 10.2% and a hospital stay average of 10.8 days (median of 5 days). Conclusions. The analyzed population has a high burden of morbidity, in which factors such as pre-surgical medical history and renal function are associated with greater post-surgical morbidity and mortality.


Subject(s)
Humans , Aortic Aneurysm, Abdominal , Endovascular Procedures , Aorta, Abdominal , Postoperative Complications , Risk Factors , Mortality
11.
Rev. colomb. cir ; 37(3): 448-454, junio 14, 2022. tab
Article in Spanish | LILACS | ID: biblio-1378727

ABSTRACT

Introducción. La peritonitis secundaria es una enfermedad con altos índices de mortalidad, por lo que se considera de gran importancia identificar los factores que inciden en ella. Método. Se realizó un estudio analítico entre 2019 y 2020 en el que se incluyeron pacientes con peritonitis secundaria, se caracterizaron las variables más relacionadas con el pronóstico, como aspectos demográficos y clínicos, y se analizó la asociación entre la mortalidad y estas variables. Resultados. La mortalidad hospitalaria fue del 30,7 %, encontrando como condiciones relacionadas con la mortalidad la ubicación de la fuente séptica en abdomen superior, la presencia de dolor en abdomen superior, atención en UCI, control del foco en la primera intervención, pacientes que cursaron con falla renal, edad del paciente y valores de hemoglobina. Conclusiones. En la cohorte estudiada se encontraron índices de mortalidad dos veces superiores a los reportados en Suramérica y 1,5 veces a los del resto del país. El mayor poder predictivo de mortalidad en el análisis bivariado fue dado por la presencia de falla renal y el valor de la hemoglobina.


Introduction. Secondary peritonitis is a disease with high mortality rates, so it is considered of great importance to identify the factors that affect it. Methods. An analytical study was carried out between 2019 and 2020 in which patients with secondary peritonitis were included, the variables most related to prognosis were characterized, such as demographic and clinical aspects, and the association between mortality and these variables was analyzed. Results. Hospital mortality was 30.7%, finding conditions related to mortality to be the location of the septic source in the upper abdomen, the presence of pain in the upper abdomen, care in the ICU, control of the focus in the first intervention, patients who underwent kidney failure, patient age, and hemoglobin values. Conclusion. Mortality rates were found in the studied cohort twice higher than those reported in South America and 1.5 times higher than those of the rest of the country. The greatest predictive power of mortality in the bivariate analysis was given by the presence of kidney failure and hemoglobin.


Subject(s)
Humans , Peritonitis , Risk Factors , General Surgery , Morbidity , Mortality
12.
Rev. Ciênc. Méd. Biol. (Impr.) ; 21(1): 31-39, maio 05,2022. tab, ilus
Article in Portuguese | LILACS | ID: biblio-1370551

ABSTRACT

Objetivo: analisar a tendência da mortalidade por câncer de laringe no Brasil e regiões no período de 1980 a 2019. Metodologia: trata-se de um estudo ecológico de série temporal. Os dados foram provenientes do SIM/DATASUS, e foram estratificados segundo faixa etária, ano, local e sexo. Foi calculada a taxa padronizada de mortalidade (TPM) e utilizada para análise de tendência, por intermédio do modelo JoinPoint. Resultados: foi possível observar que o Brasil apresentou alto número de mortes em toda série temporal com cerca de 112.693 óbitos. No tocante as suas regiões destacaram-se o Sudeste, seguido do Sul com 62.111 e 23.356 mortes pelo agravo, respectivamente. Dentre as faixas etárias analisadas, o grupo de 60-79 anos apresentou predominância em ambos os sexos, com 56.947 ocorrências. Já para o sexo, o masculino apresentou mais de 98 mil mortes em detrimento de mais de 13 mil para o feminino, uma diferença 85,6%. Avaliando a tendência, o Brasil apresentou estabilidade em boa parte da série temporal, com diminuição significativa a partir de 2009 (APC -1,6). Nas regiões, o Nordeste apresentou a maior tendência de crescimento (AAPC 2,7) e o Norte também demonstrou crescimento a partir de 1990 (APC 1,8), as demais apresentaram redução considerável e significativa, exceto Centro-oeste que não apresentou JoinPoints. Conclusão: ressalta-se a importância da revisão, melhoria e até implementação de novas políticas de rastreamento a fim de aumentar o quantitativo de diagnóstico precoce e evitar, a longo prazo, a mortalidade.


Objective: to analyze the trend of mortality from laryngeal cancer in Brazil and regions from 1980 to 2019. Methods: this is an ecological time series study. Data came from SIM/DATASUS, and were stratified according to age group, year, location and sex. Age Standard Rates (ASR) were calculated and these were used for trend analysis, performed using the Joinpoint model. Results: it was possible to observe that Brazil had a high number of deaths in the entire time series, with about 112,693 deaths. Regarding its regions, the Southeast stood out, followed by the South with 62,111 and 23,356 deaths from the disease, respectively. Among the age groups analyzed, the 60-79 age group showed a predominance in both sexes, with 56,947 occurrences. As for gender, males had more than 98 thousand deaths at the expense of more than 13 thousand for females, a difference of 85.6%. Assessing the trend, Brazil showed stability in most of the time series, with a significant decrease as of 2009 (APC -1.6). In the regions, the Northeast showed the greatest growth trend (AAPC 2.7) the North also showed growth from 1990 (APC 1.8), the others showed a considerable and significant reduction, except for the Midwest, which did not present Joinpoints. Conclusion: we emphasize the importance of reviewing, improving and even implementing new screening policies in order to increase the number of early diagnoses and prevent, in the long term, mortality.


Subject(s)
Humans , Male , Female , Aged , Laryngeal Neoplasms , Time Series Studies , Ecological Studies , Larynx , Mortality
13.
Hematol., Transfus. Cell Ther. (Impr.) ; 44(2): 218-224, Apr.-June 2022. tab
Article in English | LILACS | ID: biblio-1385064

ABSTRACT

Abstract Introduction The novel SARS-CoV-2 infection has been spreading around the world since January 2020 causing the Corona Virus Disease 2019. Leukopenia, lymphopenia and hypercoagulability with elevated D- Dimers have been described in COVID-19 patients to date. This study aimed to clarify if some blood parameters can be used as biomarkers to facilitate diagnosis and establish prognosis. Methods: We selected patients who had tested positive for SARS-CoV-2 and had had a hemogram performed between the March 15 and April 15, 2020. Socio-demographic and analytical data were obtained from 274 patients at admission in two Portuguese public hospitals. We then analyzed the hemogram parameters at admission in the intensive care and collected data on patient survival during the SARS-CoV-2 disease follow-up. The data were analyzed using appropriate statistical tests. Results: Patients requiring the intensive care unit (ICU) present an increase in leukocytes and neutrophils (+3.1 × 109/L and +6.4 × 109/L, respectively), a lymphocyte decrease and a platelet rise (-1.6 × 109/L and +60.8 × 109/L, respectively). The erythrocytes, hemoglobin and median globular volume tend to decrease (-0.5 × 1012, - 1.2 g/dL; -3 fL, respectively). The lactic acid dehydrogenase (LDH) at admission was significantly higher (+58.1 U/L). The age, sex, platelets, lymphocyte count neutrophil counts, neutrophil/lymphocyte ratio, erythrocytes and cell hemoglobin concentration mean (CHCM) are independently associated with mortality (odds ratio (OR) = 0.046, p < 0.001; OR = 0.2364, p= 0.045; OR = 9.106, p= 0.001; OR = 0.194, p= 0.033; OR = 0.062, p= 0.003; OR = 0.098, p= 0.002; OR = 9.021, p < 0.001; OR = 7.016, p= 0.007, respectively). Conclusion The hematological data at admission in the health care system can predict the mortality of the SARS-CoV-2 infection and we recommend its use in the clinical decisions and patient prognosis evaluation.


Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Young Adult , SARS-CoV-2 , COVID-19/mortality , Hematologic Diseases , Reference Standards , Blood Cell Count , Biomarkers , Mortality , Thrombophilia , Intensive Care Units , Leukopenia , Lymphopenia
14.
Hematol., Transfus. Cell Ther. (Impr.) ; 44(2): 177-185, Apr.-June 2022. tab, graf
Article in English | LILACS | ID: biblio-1385051

ABSTRACT

Abstract Introduction There is a demand to update national mortality trends data related to sickle cell disease (SCD) in Brazil. This study describes causes of death and mortality issues related to SCD using the multiple-cause-of-death methodology. Methods The annual SCD mortality data was extracted from the public databases of the Mortality Information System by researching deaths in rubric D57 "sickle-cell disorders" of the International Classification of Diseases, Tenth Revision and processed by the Multiple Cause Tabulator. Results From 2000 to 2018 in Brazil, a total of 9817 deaths related to SCD occurred during the 19-year period, as the underlying cause in 6924 (70.5%) and as the associated cause of death in 2893 (29.5%). The mean and median ages at death during the entire period were significantly lower for males, 29.4 (±19.6) and 27.5 (15.5-41.5), respectively, than for females, 33.3 (±20.3) and 31.0 (19.5-46.5), respectively. The leading SCD overall associated causes of death were septicemias (32.1%), followed by pneumonias (19.4%) and respiratory failure (18.2%). On certificates with SCD as an associated cause, the underlying causes of death were circulatory system diseases (8.7%), followed, in males, by digestive system and infectious diseases and respiratory system failures, while in females, maternal deaths, included in the chapter on pregnancy, childbirth and the puerperium, accounting for 4.6% of female deaths, were succeeded by digestive system and infectious diseases. Conclusion This study revised mortality data on death rate trends, underlying and associated causes of death, age at death and regional distribution of death in Brazil.


Subject(s)
Humans , Male , Female , Pregnancy , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Young Adult , Mortality/trends , Anemia, Sickle Cell/mortality , Maternal Mortality , Communicable Diseases , Cause of Death
15.
Rev. colomb. gastroenterol ; 37(1): 103-106, Jan.-Mar. 2022. graf
Article in English | LILACS-Express | LILACS | ID: biblio-1376913

ABSTRACT

Abstract In the spectrum of patients with intestinal obstruction, volvulus is one of the least frequent etiologies (5-15 %). Synchronous volvulus of two colonic segments in a patient is regarded as rare, with few cases reported in the literature. The present report of synchronous cecal and sigmoid volvulus documents one of them: a patient who underwent subtotal colectomy and formation of ileostomy. Although the preoperative diagnosis of this entity is rare, it should be considered in these intraoperative findings for both intraoperative management, with resection and anastomosis or resection and stoma, and postoperative management. It has a significant impact on mortality if patients are treated with broad-spectrum antibiotic coverage, given the bacterial translocation and sepsis that they experience.


Resumen En el espectro de los pacientes con obstrucción intestinal, el vólvulo es una de las etiologías menos frecuentes, siendo esta del 5 % al 15 %. La presentación sincrónica de dos segmentos colónicos volvulados en el mismo paciente se considera una entidad rara, con pocos casos reportados en la literatura. El presente caso de vólvulo sincrónico del ciego y del sigmoide documenta uno de ellos, en un paciente que se llevó a colectomía subtotal con ileostomía. Aunque el diagnóstico preoperatorio de esta entidad es poco frecuente, se debe tener en cuenta a la hora de encontrarse estos hallazgos intraquirúrgicos para el manejo tanto intraoperatorio, con resección y anastomosis o resección y estoma, como posoperatorios, lo que tiene un impacto importante en la mortalidad, si se manejan los pacientes con cubrimiento antibiótico de amplio espectro, dada la translocación bacteriana y septicemias con los que cursan estos pacientes.


Subject(s)
Humans , Male , Middle Aged , Colon, Sigmoid , Ileostomy , Cecum , Colectomy , Intestinal Volvulus , Mortality , Intestinal Obstruction
16.
Acta neurol. colomb ; 38(1): 12-22, ene.-mar. 2022. tab
Article in Spanish | LILACS | ID: biblio-1374127

ABSTRACT

RESUMEN INTRODUCCION: El ataque cerebrovascular (ACV) de etiología isquémica es una patología cuya incidencia y mortalidad aumentaron en la última década. Cuando se maneja oportunamente, mediante trombólisis como terapia inicial, mejora su desenlace y funcionalidad. En el departamento del Tolima (Colombia) no hay registros de esta patología y en el país la bibliografía al respecto es limitada. El objetivo de este estudio es evaluar los desenlaces clínicos del manejo agudo con r-tPA en los pacientes que presentaron ACV isquémico en dos instituciones de la ciudad de Ibagué, capital de dicho departamento, entre junio del 2019 y junio del 2020, e identificar los tiempos de atención hospitalaria y las principales variables asociadas con el grupo de pacientes que fallecieron. MATERIALES Y METODOS: Estudio descriptivo de corte transversal del manejo del ACV isquémico con r-tPA, en el que se describen las variables sociodemográficas, la escala NIHSS como evaluación neurológica inicial, los tiempos de atención (inicio-aguja, puerta-tac y puerta-aguja), los desenlaces postoperatorios y el Rankin modificado al egreso. RESULTADOS: Se incluyeron 38 pacientes con una media de 67,37 años, el 60,53 % fueron mujeres. La escala NIHSS al ingreso fue 13,47 puntos (DE 5,24). Los tiempos de atención fueron 183 minutos (DE 72,63) inicio-aguja, 41 minutos (RIQ 17-72) puerta-TAC y 101,50 minutos (RIQ 77 - 137,25) puerta-aguja. La mortalidad fue del 23,68 %. CONCLUSION: La mortalidad y el desenlace funcional del ACV en nuestra población fueron similares a los reportados en la literatura nacional e internacional, sin embargo, es preciso implementar protocolos de atención del infarto cerebral para incrementar el número de pacientes con desenlace favorable, acortando los tiempos de atención en toda la cadena del tratamiento adecuado del infarto cerebral.


ABSTRACT INTRODUCTION: Ischemic stroke is a growing disease in the last decade, increasing both its incidence and its mortality. However, timely thrombolysis management as initial therapy can improve both disease progression as well as an individual's functionality. In Tolima, there are no registries of this disease and in Colombia in general, the literature is limited. The objective of this study is to investigate the clinical outcomes of the acute management of ischemic stroke using r-tPA as well as identifying in-hospital treatment times, at two institutions in Ibague between 2019 and 2020. METHODS AND MATERIALS: Using a cross-sectional descriptive study, we describe the management of ischemic stroke using r-tPA, describing sociodemographic variables, NIHSS scale as the initial neurological evaluation, in-hospital treatment times (symptoms-to-needle, door-to-TAC, door-to-needle), the clinical outcomes, and lastly the modified Rankin score upon discharge. RESULTS: We included 38 patients with median age of 67,37 years, 60,53 % were females. The initial average NIHSS scale upon admission was 13,47 (DE 5,24). In-hospital attention time averages were: symptoms-to-needle 183 minutes (DE 72,63), door-to-CAT 41 minutes (RIQ 17-72), and door-to-needle 101,50 minutes (RIQ 77-137,25). Overall the rate of mortality was 23,68 %. CONCLUSIONS: Mortality and functionality outcomes of the stroke population observed was similar to previously reported, both nationally and internationally. However, protocols should be implemented for the timely ischemic stroke management to improve the number of patients with favorable outcomes, by reducing the in-hospital attention times in all areas of the management chain.


Subject(s)
Mortality , Colombia , Stroke
17.
Rev. Hosp. Ital. B. Aires (2004) ; 42(1): 12-20, mar. 2022. graf, ilus, tab
Article in Spanish | LILACS, BINACIS, UNISALUD | ID: biblio-1368801

ABSTRACT

Introducción: determinar la causa de muerte de los pacientes internados con enfermedad cardiovascular es de suma importancia para poder tomar medidas y así mejorar la calidad su atención y prevenir muertes evitables. Objetivos: determinar las principales causas de muerte durante la internación por enfermedades cardiovasculares. Desarrollar y validar un algoritmo para clasificar automáticamente a los pacientes fallecidos durante la internación con enfermedades cardiovasculares Diseño del estudio: estudio exploratorio retrospectivo. Desarrollo de un algoritmo de clasificación. Resultados: del total de 6161 pacientes, el 21,3% (1316) se internaron por causas cardiovasculares; las enfermedades cerebrovasculares representan el 30,7%, la insuficiencia cardíaca el 24,9% y las enfermedades cardíacas isquémicas el 14%. El algoritmo de clasificación según motivo de internación cardiovascular vs. no cardiovascular alcanzó una precisión de 0,9546 (IC 95%: 0,9351-0,9696). El algoritmo de clasificación de causa específica de internación cardiovascular alcanzó una precisión global de 0,9407 (IC 95%: 0,8866-0,9741). Conclusiones: la enfermedad cardiovascular representa el 21,3% de los motivos de internación de pacientes que fallecen durante su desarrollo. Los algoritmos presentaron en general buena performance, particularmente el de clasificación del motivo de internación cardiovascular y no cardiovascular y el clasificador según causa específica de internación cardiovascular. (AU)


Introduction: determining the cause of death of hospitalized patients with cardiovascular disease is of the utmost importance in order to take measures and thus improve the quality of care of these patients and prevent preventable deaths. Objectives: to determine the main causes of death during hospitalization due to cardiovascular diseases.To development and validate a natural language processing algorithm to automatically classify deceased patients according to their cause for hospitalization. Design: retrospective exploratory study. Development of a natural language processing classification algorithm. Results: of the total 6161 patients in our sample who died during hospitalization, 21.3% (1316) were hospitalized due to cardiovascular causes. The stroke represent 30.7%, heart failure 24.9%, and ischemic cardiac disease 14%. The classification algorithm for detecting cardiovascular vs. Non-cardiovascular admission diagnoses yielded an accuracy of 0.9546 (95% CI 0.9351, 0.9696), the algorithm for detecting specific cardiovascular cause of admission resulted in an overall accuracy of 0.9407 (95% CI 0.8866, 0.9741). Conclusions: cardiovascular disease represents 21.3% of the reasons for hospitalization of patients who die during hospital stays. The classification algorithms generally showed good performance, particularly the classification of cardiovascular vs non-cardiovascular cause for admission and the specific cardiovascular admission cause classifier. (AU)


Subject(s)
Humans , Artificial Intelligence/statistics & numerical data , Cerebrovascular Disorders/mortality , Myocardial Ischemia/mortality , Heart Failure/mortality , Hospitalization , Quality of Health Care , Algorithms , Reproducibility of Results , Factor Analysis, Statistical , Mortality , Cause of Death , Electronic Health Records
18.
Rev. Bras. Saúde Mater. Infant. (Online) ; 22(1): 115-119, Jan.-Mar. 2022. tab
Article in English | LILACS | ID: biblio-1376209

ABSTRACT

Abstract Objectives: evaluate maternal mortality from January 2019 to January 2020 in the state of Ceará. Methods: this is a descriptive and retrospective ecological study. Data collection was carried out from October to November 2020, considering the time interval from January 2019 to January 2020, through information registered in a public domain database in the State of Ceará, Brazil. The variables considered to outline the profile of maternal deaths were: age group, causes, marital status, color/race and education. Data analysis was performed using descriptive statistics by frequency distribution and presented through tables. Results: 135 maternal deaths were registered, considering external, direct (most prevalent), indirect and late causes. The maternal mortality ratio in Ceará was 60.43%, whose profile of deaths was characterized by women with incomplete higher education (41.5%), brown (80%), in their 20-29 years (43%) and single (66.7%). Conclusion: the information in this study is extremely importance, as it allows the understanding of a key population, women, in addition to assisting in the design of strategies for coping with maternal mortality.


Resumo Objetivos: avaliar a mortalidade materna de janeiro de 2019 a janeiro de 2020 no estado do Ceará. Métodos: trata-se de um estudo ecológico descritivo e retrospectivo. A coleta de dados foi realizada no período outubro a novembro de 2020, considerando o intervalo temporal de janeiro de 2019 a janeiro de 2020, através das informações registradas em banco de dados de domínio público do estado do Ceará. As variáveis consideradas para delinear o perfil dos óbitos maternos foram: faixa etária, as causas, estado civil, cor/raça e escolaridade. A análise dos dados ocorreu pela estatística descritiva por distribuição de frequências e foi apresentada por meio de tabelas. Resultados: foram registrados 135 óbitos maternos, considerando causas externas, diretas (mais prevalentes), indiretas e tardias. A razão de mortalidade materna no Ceará foi de 60.43%, cujo perfil dos óbitos foi caracterizado por mulheres com nível superior incompleto (41.5%), pardas (80%), na faixa etária de 20-29 anos (43%) e solteiras (66.7%). Conclusão: as informações apresentadas neste estudo são de extrema relevância, pois possibilitam a compreensão de uma população-chave, as mulheres, além de auxiliar no delineamento de estratégias para o enfrentamento da mortalidade materna.


Subject(s)
Humans , Female , Pregnancy , Socioeconomic Factors , Maternal Mortality , Mortality , Cause of Death , Brazil , Ecological Studies
19.
Rio de Janeiro; SES-RJ; 01/02/2022. 50 p.
Non-conventional in Portuguese | LILACS, SES-RJ | ID: biblio-1370087

ABSTRACT

O Boletim de Análise da Situação de Saúde ­ BASIS, nasce da necessidade da produção de informação que permita descrever, explicar e avaliar o perfil de saúde-doença da população, incluindo os agravos ou problemas de saúde, assim como seus determinantes de uma forma mais global, uma vez que cada área técnica já vem produzindo e divulgando especificamente sobre as doenças e agravos sob sua vigilância.


Subject(s)
Diagnosis of Health Situation , Unified Health System , Health-Disease Process , Oral Health , Mortality , Environmental Monitoring , Delivery of Health Care , Public Health Surveillance , Data Analysis , Mental Health Services
20.
Rev. Méd. Inst. Mex. Seguro Soc ; 60(1): 33-39, 17-feb-2022. tab
Article in Spanish | LILACS | ID: biblio-1359821

ABSTRACT

Introducción: en diciembre de 2019 se reportó por primera vez un brote de COVID-19. Esta enfermedad ha ocasionado millones de muertes a nivel mundial. A la fecha se han probado multiples fármacos, sin encontrar un tratamiento eficaz aún. Objetivo: describir la evolución y el tratamiento farmacológico utilizado en pacientes hospitalizados por COVID-19. Material y métodos: estudio observacional en 200 pacientes hospitalizados por COVID-19 en un hospital regional de Acapulco que ingresaron entre marzo y julio de 2020. Se identificaron las características, el tratamiento farmacológico y la evolución de los pacientes. Se realizó analisis univarido, bivariado y multivariado. Resultados: el 60% de los pacientes fueron del sexo masculino, 83% presentaron al menos una comorbilidad, 56% fallecieron. El fármaco más utilizado fue la enoxaparina, del cual recibir dosis de 60 mg se asoció a menor riesgo de fallecer comparado con recibir 40 mg. Haber recibido hidroxicloroquina, metilprednisolona, moxifloxacino y tener 60 años o más se asoció a un mayor riesgo de morir. Conclusiones: se presentó una elevada mortalidad. El fármaco más utilizado fue la enoxaparina, del cual utilizar dosis de 60 mg disminuyó el riesgo de fallecer


Background: In December 2019, an outbreak of COVID-19 was reported for the first time. This disease has caused millions of deaths worldwide. To date multiple drugs have been tried, without finding an effective treatment yet. Objective: To describe the evolution and the pharmacological treatment used in patients hospitalized due to COVID-19. Material and methods: Observational study in 200 patients hospitalized due to COVID-19 in a regional hospital of Acapulco who were admitted between March and July 2020. The characteristics, pharmacological treatment and evolution of the patients were identified. Univariate, bivariate and multivariate analyses were performed. Results: 60% of the patients were male, 83% had at least one comorbidity, 56% died. The most used drug was enoxaparin, of which receiving a 60 mg dose was associated with a lower risk of death, compared to receiving 40 mg. Having received hydroxychloroquine, methylprednisolone, moxifloxacin and being 60 years or older was associated with a higher risk of progressing to death. Conclusions: There was a high mortality. The most used drug was enoxaparin, of which using doses of 60 mg reduced the risk of death


Subject(s)
Humans , Animals , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Therapeutics , Mortality , Drug Interactions , COVID-19 , Comorbidity , Enoxaparin , Mexico
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