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El objetivo de esta revisión fue examinar la efectividad del cuestionario Global de actividad física y el Cuestionario Internacional de actividad física forma corta, en relación con las evaluaciones prácticas que valoran la condición física saludable como instrumento de valoración del sedentarismo. Se realizó una búsqueda digital en bases de datos científicas de alto factor de impacto según referencia electrónica de Scimagojr, Scopus, Pubmed y Ebsco. La efectividad del cuestionario internacional y global de actividad física, en la valoración del sedentarismo y prescripción del ejercicio físico parecen condicionados en comparación con las evaluaciones prácticas, que valoran factores similares, sin embargo, proveen indicadores básicos que debe tomarse en cuenta al inicio de prescribir actividad física, se evidencia la necesidad de aplicar parámetros de nivel sedentario y aptitud física en población adulta establecidos por evaluaciones prácticas(AU)
The objective of this review was to examine the effectiveness of the Global Physical Activity Questionnaire and the International Short Form Physical Activity Questionnaire, in relation to practical evaluations that assess healthy physical condition as an instrument for assessing sedentary lifestyle A digital search was conducted in scientific databases of high impact factor according to electronic reference of Scimagojr, Scopus, Pubmed, and Ebsco. The effectiveness of the international and global physical activity questionnaire, in assessing sedentary lifestyle and prescribing physical exercise seem conditioned, compared to practical evaluations, which assess similar factors, however they provide basic indicators that should be taken into account at the beginning of prescribing physical activity, the need to apply sedentary level and physical fitness parameters in the adult population established by practical evaluations is evident(AU)
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Humains , Organisation mondiale de la santé , Activité motrice/physiologie , Enquêtes et questionnaires/normesRésumé
Objective:To observe the clinical efficacy of acupuncture plus umbilicus application with Chinese medicine for detrusor underactivity.Methods:A total of 46 male patients with detrusor underactivity who were admitted to our hospital between January and December 2017 were randomized into a control group and an observation group,with 23 cases in each group.The control group received intermittent catheterization and routine nursing,and the observation group was treated with acupuncture plus umbilicus application with Chinese medicine on the basis of the treatment of the control group.The comprehensive efficacy,the improvement of bladder urine residue and maximum flow rate of the two groups were observed.Results:No cases dropped out in the two groups.After the intervention,the total effective rate of the observation group was 78.3%,which was significantly higher than 52.2% of the control group (P<0.05).After intervention,the improvements of bladder urine residue and maximum flow rate in the observation group were statistically different from those in the control group (both P<0.05).Conclusion:The combination of acupuncture and umbilicus application with Chinese medicine added on the basis of intermittent catheterization and routine nursing has a certain effect in treating male patients with detrusor underactivity,and is worth further clinical study.
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Objective To study the impact of Yindan Xinnaotong capsules on learning and memory abilities and Bcl-2 and Bax expressions in the hippocampal CA1 region of rats with vascular dementia (VD).Methods All rats were randomly divided into normal group,sham-operated group,vehicle group and low-,middle-and high-dose Yindan Xinnaotong capsule treatment groups.The animal models of VD in all the groups,excepted the normal group and sham-operated group,were established by two-vesssel-occlusion+sodium nitroprusside method.Yindan Xinnaotong capsule treatment groups were intragastrically given Yindan Xinnaotong capsules by dose of 0.24 g/(kg·d),0.48 g/(kg· d) and 0.96 g/(kg ·d) for 28 days,respectively.The Bcl-2 and Bax expressions were detected by immunohistochemistry staining; the capabilities of learning and memory were tested by Morris water maze.Results Morris water maze test showed that the escape latency of the vehicle group was (94.32±16.53),which was significantly longer than that of the normal group and sham-operated group (P<0.05); the middle dose and high dose Yindan Xinnaotong capsule treatment groups had the escape latency of (74.36±15.67) and (65.73 ±14.84),which were significantly shorter than that of vehicle group (P<0.05).As compared with the normal group and sham-operated groups,number of the number of crossing the platform and target quadrant dwell time in the vehicle group were significantly reduced (P<0.05); in the middle dose and high dose Yindan Xinnaotong capsule treatment group,crossing the platform and the target quadrant dwell time were (2.30 ±0.42) and (79.85 ±5.58),(2.71 ±0.45) and (83.38 ±5.36),which were significantly increased than those in the vehicle group (1.15±0.24) and (66.80±7.20,P<0.05).As compared with those in the normal group and sham-operated group,the Bcl-2 and Bax positive expressions in the other groups were significantly increased (P<0.05),and the changes in the vehicle group were the most obvious (P<0.05); as compared with those in the vehicle group,the Bcl-2 expression were significantly increased and the Bax expression was obviously reduced in groups of middle dose and high dose (P<0.05).Conclusion Yindan Xinnaotong capsules can improve the learning and memory abilities; it can also increase the Bcl-2 expression and decrease the Bax expression.
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Background The characteristics of anisometropic amblyopia in ocular morphology are becoming a hot topic in amblyopia field.And the interocular difference in corneal parameters of anisometropic amblyopia is to be understood here.Corneal topography is a non-invasive method for in vivo corneal examination and applied in our study.Objective This study was to investigate the interocular difference of corneal topography in anisometropic amblyopic patients Methods This was a serial cases observation.Thirty anisometropic amblyopes were selected in Center for Optometry and Visual Science,People's Hospital of Guangxi Zhuang Autonomous Region.The patients were divided into amblyopic eye group and fellow eye group based on the best corrected distance visual acuity.Corneal topography was examined with Orbscan Ⅱ z,and corneal morphological parameters such as Diff values of the anterior and posterior corneal surface,Sim K 's astigmatism,Kmax,angle kappa and central corneal thickness (CCT) were measured.The interocular differences in these parameters were evaluated by paired t test,and the correlations in these parameters between the amblyopic eyes and the fellow eyes were analyzed by Pearson linear correlation and simple regression analysis.Results The Diff values of the anterior corneal surface were (0.011±0.006)mm and (0.011±0.017)mm,and those in the posterior corneal surface were (0.031 ±0.012)mm and (0.026 ±0.008)mm in the amblyopic eye group and the fellow eye group,respectively.In addition,Sim K's astigmatism were (1.8± 1.1)D and (1.1 ±0.6) D,JCC were (77±80) °and (100±80) °,J0 values were (-0.17±0.72) D and (0.02±0.41) D,J45 values were (-0.16±0.79) D and (0.13 ±0.48) D,CCT values were (551 ±37) μm and (551 ±31) μm,angle kappa values were (6.4± 1.4) ° and (4.9 ± 1.2) ° in the amblyopic eye group and the fellow eye group,respectively.Significant differences were found in the Diff values of the anterior and posterior corneal surface,Sim K's astigmatism and angle kappa between the two groups (t=-3.041,P=0.005 ;t=-4.317,P=0.000 ;t=-4.571,P=0.000).Pearson's linear correlation test demonstrated significant interocular positive correlations in parameters such as the anterior corneal surface Diff values (r =0.444),J0 (r =0.383),posterior Diff values (r =0.600),and Sim K 's astigmatism (r =0.479),and CCT (r =0.948,P<0.05).The linear regression equation between the two groups was Y =-0.005 +1.392X (R2 =0.197,F=6.858,P=0.014) in the Diff values in the anterior corneal surface,Y =-0.013+0.421X (R2=0.360,F=15.761,P=0.000) in the Diff values in the posterior corneal surface,Y =0.616+0.27X (R2=0.230,F=8.348,P=0.007) in the Sim K's astigmatism,Y=0.060+0.219X (R2 =0.147,F=4.814,P=0.037) in theJo and Y=i08.289+0.804X (R2 =0.899,F=250.293,P=0.000) in CCT.Conclusions Corneal morphological interocular differences exist significantly in anisometropic amblyopic patients.
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Visual perceptual learning refers to the special improvement of perceptual performance benefit from repetitive training with a visual task.A typical time course of visual perceptual learning presents an initial rapid improvement,and then gradually processes like an asymptote in gain.During the process of perceptual learning,the influence of critical amount and perceptual learning rules on learning effect,memory consolidation and interference,and the role of sleep on preventing interference and promoting consolidation in perceptual learning,all get involved.This article reviewed the aforesaid content and then elaborated some strategies in application of visual perceptual learning in the treatment of amblyopia.
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<p><b>OBJECTIVE</b>To explore young hypertensive people's vascular endothelial dysfunction and the early atherosclerosis changes.</p><p><b>METHODS</b>Rural youth subjects aged 20 to 35 in 6 villages were randomly selected from 20 villages of 3 townships, including Qili, Laojun and Shayan, in Hanzhong, Shanxi, China, from March to April of 2005, to survey their blood pressure and other related factors. 97 subjects with high blood pressure (hypertensive group) were detected while 400 with normal blood pressure (normal group). We measured their brachial artery flow-mediated vascular endothelial-dependent diastolic function (FMD) and the carotid intima-media thickness (IMT) by high resolution vascular ultrasound method, and other biochemical indexes.</p><p><b>RESULTS</b>The body mass index (BMI) ((24.7 ± 4.3) kg/m²), waistline ((84.1 ± 11.7) cm), hipline ((92.5 ± 7.4) cm), TC ((4.6 ± 0.8) mmol/L), LDL-C ((2.8 ± 0.5) mmol/L), TG ((1.7 ± 1.1) mmol/L) and the blood insulin (INS) ((8.6 ± 4.4) mIu/L) were all significantly increased in young hypertensive group than those in normotensive group (respectively were (22.1 ± 3.0) kg/m(2), (76.7 ± 8.9) cm, (88.9 ± 5.6) cm, (4.3 ± 0.7) mmol/L, (2.6 ± 0.4) mmol/L, (1.4 ± 0.8) mmol/L and (6.9 ± 2.1) mIu/L) (P < 0.05). The FMD of the brachial artery in hypertensive group was markedly lower than normal group ((0.103 ± 0.04)% and (0.117 ± 0.05)%, P < 0.05). The IMT of two groups were (0.49 ± 0.07) mm and (0.48 ± 0.07) mm, but there was no statistically significant differences (P > 0.05).</p><p><b>CONCLUSION</b>Young hypertensive people with a few cardiovascular risk factors earlier appear dysfunction of the flow-mediated vascular endothelial-dependent dilation, which is prior to the increase in carotid IMT.</p>
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Adulte , Femelle , Humains , Mâle , Jeune adulte , Artères , Anatomopathologie , Athérosclérose , Anatomopathologie , Pression sanguine , Endothélium vasculaire , Anatomopathologie , Hypertension artérielle , Anatomopathologie , Facteurs de risqueRésumé
<p><b>OBJECTIVE</b>Salt-sensitivity is associated with more severe target organ injury and higher mortality in patients with essential hypertension. We compared the vascular endothelial function between salt-sensitive subjects (SS) and non-salt-sensitive subjects (NSS) with normal or mildly increased blood pressure.</p><p><b>METHODS</b>Ninety-nine subjects (aged 16 - 60 years) with normal blood pressure or mild hypertension (degree 1) were enrolled. The test program included 3 days baseline investigation, 1 week low-salt loading phase and 1 week high-salt loading phase. Endothelial function was assessed by measuring the flow mediated dilatation (FMD) of the brachial artery using high resolution ultrasound.</p><p><b>RESULTS</b>There was 17.2% SS. Plasma NOx level [(61.2 ± 13.3) µmol/L vs (82.5 ± 14.6) µmol/L, P < 0.05] and FMD [(10.2 ± 2.5)% vs (14.5 ± 1.6)%, P < 0.05] were significantly lower in SS subjects than in NSS subjects.</p><p><b>CONCLUSION</b>Vascular endothelial dysfunction was evidenced in SS subjects with normal blood pressure or in the early stage of hypertension.</p>
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Adolescent , Adulte , Femelle , Humains , Mâle , Adulte d'âge moyen , Jeune adulte , Pression sanguine , Études cas-témoins , Endothélium , Métabolisme , Endothélium vasculaire , Métabolisme , Sodium alimentaireRésumé
<p><b>OBJECTIVE</b>To investigate the prevalence, type and distribution of astigmatism in children with amblyopia.</p><p><b>METHODS</b>A total of 2023 children with amblyopia (aged 4-11 years, 3657 eyes) were recruited. The prevalence of astigmatism was investigated.</p><p><b>RESULTS</b>Of the 3657 amblyopic eyes, 91.9% presented astigmatism (≥0.5 D). The proportion of eyes with astigmatism decreased with the increasing age. Compound hyperopic astigmatism was the most common type of astigmatism (38.8%) and its prevalence increased with the increasing age in children with amblyopia. Astigmatism with the rule was the most common (90.1%) in the axial distribution test. There were statistical significances in the axial distribution of astigmatism in different age groups. Statistical significances were also found in the degree, type and axis of astigmatism among the children with mild, moderate and severe amblyopia (P<0.05).</p><p><b>CONCLUSIONS</b>The prevalence of astigmatism in children with amblyopia is high but is reduced with age. The age and the degree of amblyopia might be influential factors in the distribution of astigmatism.</p>
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Enfant , Enfant d'âge préscolaire , Femelle , Humains , Mâle , Amblyopie , Épidémiologie , Astigmatisme , Épidémiologie , Chine , Épidémiologie , PrévalenceRésumé
<p><b>OBJECTIVE</b>To establish a uremic apolipoprotein E knockout (apoE-/-) mouse model and explore the relationship between accelerated atherosclerosis and Treg/Teff balance.</p><p><b>METHODS</b>Using apoE-/- mice with C57BL/6J background, uremic apoE-/- mice were created by electrocautery of the right kidney and nephrectomy of the left, and the control apoE-/- mice received a sham-operation. Two weeks after inducing uremia, the renal function of the mice were evaluated to assess the validity of the model. Ten weeks after the operation, blood samples were obtained from the mice to assess the renal function and serum total cholesterol (TCH); the serum concentrations of transforming growth factor-beta(1) (TGF-beta(1)) and interferon-gamma (IFN-gamma) were detected by ELISA, and CD4(+)CD25(+)Foxp3(+)Treg ratio in the spleen was determined by flow cytometry. RT-PCR was used to detect the expression of Foxp3 and IFN-gamma mRNA in the aorta, and oil red O staining used to investigate the relative atherosclerotic area on the frozen sections of the aortic root. The correlation between the renal function parameters and Treg quantity was analyzed.</p><p><b>RESULTS</b>Renal function detection confirmed successful establishment of the uremic apoE-/- mouse model. Ten weeks after the operation, the relative atherosclerotic plaque area in the aortic root plaque increased significantly, the spleen Treg ratio decreased, the serum concentrations of TGF-beta(1) decreased and IFN-gamma and TCH increased, the expression of aortic Foxp3 mRNA decreased and IFN-gamma mRNA increased as compared with those in the control apoE-/- mice. A significant inverse correlation was found between the renal function parameters and Treg quantity in uremic apoE-/- mice.</p><p><b>CONCLUSION</b>In uremic apoE-/- mice, accelerated aortic atherosclerosis is correlated to the T cell subset (Treg/Teff) imbalance shown by decreased quantity and impaired function of Treg and enhanced activity of Teff.</p>
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Animaux , Femelle , Mâle , Souris , Aorte , Anatomopathologie , Apolipoprotéines E , Génétique , Athérosclérose , Allergie et immunologie , Anatomopathologie , Cholestérol , Sang , Évolution de la maladie , Facteurs de transcription Forkhead , Métabolisme , Techniques de knock-out de gènes , Interféron gamma , Sang , Métabolisme , Répartition aléatoire , Sous-populations de lymphocytes T , Allergie et immunologie , Lymphocytes T régulateurs , Allergie et immunologie , Facteur de croissance transformant bêta-1 , Sang , Urémie , Génétique , Allergie et immunologieRésumé
<p><b>OBJECTIVE</b>Essential hypertension may begin at childhood. The aim of this study is to identify the risk factors of hypertension and detect the evolvement tracking of blood pressure in childhood.</p><p><b>METHODS</b>In this study, we followed up blood pressure changes in 4623 school children (6 - 15 years-old) from 1987 to 2005 in Hanzhong rural area. A total of 152 children were grouped to higher blood pressure group [systolic blood pressure (P(SBP)) >or= 75(th) (P(75))] and 140 children grouped to normal blood pressure group [P(SBP) < 50(th) (P(50))] and their blood pressure were re-measure 18-years later.</p><p><b>RESULTS</b>The total follow-up rate was 70.2%. Follow-up blood pressure was significantly higher in higher blood pressure group at baseline than that in normal blood pressure group at baseline (P < 0.05). The hypertension rate at follow up was significantly higher in higher blood pressure group at baseline than that in normal blood pressure group at baseline (28.0% vs. 4.1%, P < 0.01). The risk for hypertension was 6.88 greater in higher blood pressure group at baseline than that in normal blood pressure group at baseline.</p><p><b>CONCLUSIONS</b>Higher blood pressure at childhood is a risk of developing hypertension at adulthood.</p>
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Adolescent , Enfant , Humains , Pression sanguine , Physiologie , Mesure de la pression artérielle , Études de suivi , Hypertension artérielle , Facteurs de risqueRésumé
Objective To study the effects of salt sensitivity on evolution of blood pressure and develope- ment to hypertension from adolescents to youth.Methods A baseline survey was carried out in 4623 adolescents aged 6-15 years old in Hanzhong rural area in 1987,310 of them were recruited for determination of salt sensitiv- ity using the tests of oral saline load and furosemide sodium-volume depletion.Salt sensitivity (SS) were diag- nosed in 101 while 209 subjects as no-sah sensitivity (NSS).This cohort of adolescents were followed up for av- erage 18 years.Results The response rate for this cohort of adolescents was 71.9%.At the end of follow up period,BP in subjects with baseline SS was higher in youth than that in NSS (SBP:122.9?13.1 vs 117.3?12.4, P
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<p><b>OBJECTIVE</b>To assess the efficacy and safety of Zhongyan-4 (ZY-4, a Chinese herbal preparation worked out according to the therapeutic principle of supplementing qi, nourishing Yin, clearing heat and detoxication) in treating HIV/AIDS patients in the early or middle stage.</p><p><b>METHODS</b>Adopted was randomized double-blinded and placebo-parallel-controlled method, with 72 HIV/AIDS patients randomly divided into the ZY-4 group (36 patients) treated with ZY-4 and the control group (36 patients) treated with placebo. The treatment course was six months. The index of CD(4)(+), CD(8)(+) counts, body weight, clinical symptom scoring were estimated at 4 time points (0, 1, 3 and 6 month in the course), and also the viral load before and after treatment. The whole course of observation was completed in 63 patients, 30 in the ZY-4 group and 33 in the control group.</p><p><b>RESULTS</b>CD(4)(+) count in the ZY-4 group got elevated by 7.70 +/- 150.96/mm(3) on average, while that in the control group lowered by 27.33 +/- 85.28/mm(3). Fifteen out of the 30 patients in the ZY-4 group had their CD(4)(+) count increased, which was evidently much higher than that in the control group (8/33, P < 0.05), suggesting that the efficacy of ZY-4 is superior to that of placebo in elevating CD(4)(+) count. Moreover, ZY-4 showed actions in elevating CD(45)RA(+) and CD(8)(+) count, reducing HIV virus load, improving clinical symptom/sign and increasing body weight of patients. No obvious adverse reaction was found in the clinical trial.</p><p><b>CONCLUSION</b>ZY-4 has an immunity-protective and/or rebuilding function in HIV/AIDS patients in the early and middle stage, and also shows effects in lowering viral load, increasing body weight and improving symptoms and signs to a certain degree.</p>
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Adulte , Femelle , Humains , Mâle , Adulte d'âge moyen , Syndrome d'immunodéficience acquise , Traitement médicamenteux , Allergie et immunologie , Virologie , Agents antiVIH , Utilisations thérapeutiques , Poids , Numération des lymphocytes CD4 , Rapport CD4-CD8 , Méthode en double aveugle , Médicaments issus de plantes chinoises , Utilisations thérapeutiques , Infections à VIH , Traitement médicamenteux , Allergie et immunologie , Virologie , Antigènes CD45 , Phytothérapie , Charge viraleRésumé
<p><b>OBJECTIVE</b>Salt-sensitivity plays an important role in essential hypertension and is associated with more severe target organ injury and higher mortality in patients with essential hypertension. However, the pathologic mechanism of salt-sensitivity is poorly understood and endothelial dysfunction might be involved in salt-sensitive hypertension. We, therefore, observed the endothelial function changes by measuring plasma and urine nitric oxide (NO) concentrations in salt-sensitive (SS) normotensive and mild hypertensive subjects underwent various salt loading protocols and the effects of potassium supplement.</p><p><b>METHODS</b>Thirty-nine normotensive and mild hypertensive subjects (< 160/100 mm Hg), aged 16-60, were enrolled and the study protocol is as follows: 3 days baseline investigation, 1 week low-salt loading (3 g/day), 1 week. high-salt loading (18 g/day) and 1 week high-salt loading plus potassium chloride (4.5 g/day).</p><p><b>RESULTS</b>Plasma and urine NO levels were significantly lower in SS (n = 8) subjects at baseline, low-salt and high-salt loading phases compared with salt-resistant subjects (SR, n = 31) and oral potassium supplement to SS subjects with high salt loading significantly increased plasma and urine NO levels.</p><p><b>CONCLUSION</b>Endothelial function is impaired in normotensive and mild hypertensive SS subjects. Oral potassium supplement could improve endothelial function in normotensive and mild hypertensive SS subjects.</p>
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Adulte , Femelle , Humains , Mâle , Antihypertenseurs , Pression sanguine , Endothélium , Physiologie , Hypertension artérielle , Épidémiologie , Monoxyde d'azote , Sang , Urine , Potassium alimentaireRésumé
<p><b>OBJECTIVE</b>To evaluate the effects of traditional Chinese medicine in 461 cases of severe acute respiratory syndrome(SARS) on glucocorticoid's dosage.</p><p><b>METHOD</b>By using the polycentric nonrandomized concurrent controled trial and under the condition of glucocorticoid use, the patierts were divided into two groups: the integrated traditional Chinese and western mendicine(ITCWM) and simplicity western mendicine alone(WM). The observation indexes were time in hospital, pneumonia duration, mortality, glucocorticoid's gross dosage, glucocorticoid's average dosage of days and glucocorticoid use time.</p><p><b>RESULT</b>In the ITCWM group, average time in hospital was shortened (P = 0.058), pneumonia duration was shortened (P = 0.057), mortality fell (P = -0.001). The median of glucocorticoid' s gross dosage was 1,277.0 mg x d(-1) in the ITCWM group, and that was 1,680.0 mg x d(-1) in the WM group (P = 0.083). The median of glucocorticoid's average dosage of days was 84.40 mg x d(-1) in the ITCWM group, and that was 115.33 mg x d(-1) in the WM group (P = 0.025). According to the analysis of 461 cases divided by stages and different ponderance, within 7 days after illness, in the ITCWM group, the glucocorticoid' s average dosage decreased. In the common type, the dosage in the ITCWM and in the WM was 146.43 mg x d(-1), and 183.64 mg x d(-1), respectively (P = 0.057), in the severe type, that was 137.71 and 177.86 mg x d(-1), respectively (P = 0.001).</p><p><b>CONCLUSION</b>Compared with the group of simplicity western mendicine, in the group of integratived Chinese and western mendicine, time in hospital shorten, pneumonia duration shorten, mortality fall, simultaneity, glucocorticoid's average dosage is decreased. The use of TCM in the forepart of treatment can be capable of decreasing glucocorticoid's dosage.</p>
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Adulte , Femelle , Humains , Mâle , Adulte d'âge moyen , Relation dose-effet des médicaments , Association de médicaments , Médicaments issus de plantes chinoises , Utilisations thérapeutiques , Durée du séjour , Méthylprednisolone , Utilisations thérapeutiques , Phytothérapie , Pneumopathie infectieuse , Traitement médicamenteux , Syndrome respiratoire aigu sévère , Traitement médicamenteux , MortalitéRésumé
<p><b>OBJECTIVE</b>To investigate the friction and wear behavior of different human enamels.</p><p><b>METHODS</b>24 enamel samples selected from aged, young permanent and faded deciduous teeth were classified into 3 groups and slid against artificial porcelain teeth in the presence of artificial saliva on an oscillating friction and wear test rig. The wear volume loss, microhardness and toughness of each group of the enamel specimens were measured, the wear scars were observed with a scanning electron microscope, and the elemental compositions of Ca, P, and Si of the wear scar and wear debris were determined with an energy dispersion spectrometer.</p><p><b>RESULTS</b>The wear volume losses of aged, young permanent and deciduous tooth enamels are (2.40 +/- 1.10) x 10(-12) m(3), (3.50 +/- 1.83) x 10(-12) m(3) and (4.86 +/- 2.49) x 10(-12) m(3). The data of aged tooth enamels are statistically greater than that of deciduous tooth enamels (P < 0.05). There is no significant difference between the wear volume loss of aged and young permanent tooth enamels or between the young permanent and deciduous tooth enamels (P > 0.05). However, the friction and wear behavior of each group of enamel specimens is different from each other.</p><p><b>CONCLUSIONS</b>In the present testing condition, the wear scars of each kind of enamel specimens is characterized by ploughing and cracking. The different wear resistance of the three kinds of enamels is attributed to the different microstructure of the enamel, while the hardness and toughness of the enamels are not correlated with the wear resistance.</p>
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Adolescent , Sujet âgé de 80 ans ou plus , Enfant , Enfant d'âge préscolaire , Femelle , Humains , Nourrisson , Nouveau-né , Mâle , Adulte d'âge moyen , Facteurs âges , Émail dentaire , Anatomopathologie , Denture permanente , Techniques in vitro , Abrasion dentaire , Anatomopathologie , Dent de laitRésumé
<p><b>OBJECTIVES</b>To determine changes of insulin-like growth factor-1 (IGF-1) and IGF binding protein-3 (IGFBP-3) in serum samples from benign prostatic hyperplasia (BPH) patients and to evaluate the value of these molecules as possible etiologic factors for BPH.</p><p><b>METHODS</b>The serum IGF-1 and IGFBP-3 levels were measured with immunoradiometric assay(IRMA) in 64 cases of BPH and in 30 healthy subjects as controls. The cases of BPH were divided into 3 groups according to the prostate volume(PV). There were 18 cases(PV < or = 30 ml) in group A, 24 cases(PV31 approximately 50 ml) in group B, 22 cases(PV > or = 50 ml) in group C.</p><p><b>RESULTS</b>There were no statistical differences between the levels of Both IGF-1 and IGFBP-3 in BPH groups and healthy groups (both P > 0.05), but there were statistical differences among three groups of BPH. Both IGF-1 and IGFBP-3 levels in group C of BPH were significantly higher than those in group A (both P < 0.05). A positive correlation between the serum levels of IGF-1 and PV displayed(r = 0.58), as well as IGFBP-3 (r = 0.48).</p><p><b>CONCLUSIONS</b>Together these observations implicate IGF-1 and IGFBP-3 as important factors during the progression of BPH. It shows the value of non-operation treatment for this disease.</p>
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Sujet âgé , Humains , Mâle , Protéine-3 de liaison aux IGF , Sang , Facteur de croissance IGF-I , Hyperplasie de la prostate , Sang , Dosage radioimmunologiqueRésumé
Objective To explore the correlation of city school-aged children′s intelligence quotients(IQ) with family factors.Methods Picking up 180 healthy children which aged 10-14 and their parents.Children′s IQ were tested with Wechsler intelligence Scale for Children- Revised(WISC-R).Their parents were investigated by using the questionnaire designed by ourselves about some factors of family which includes Eysenck Personality Questionnaire(EPQ), Home Education Index Measuring Scale (HEIMS),and so on. We analyzed the associations between children′s IQ and family factors with the applicable data about 114 only child. Results Multiple stepwise regression analyses show that some factors have significant effects on IQ of children(P
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Objective To study the effects of hormone,anesthetie and contrast medium on the activities of collagenase lysis.Methods Nuclear tissues were divided into equal amount for different groups and same units of collagenase were used for the lysis.The only difference in the control group from experimental groups was that there were no dexamethasone,lidocaine or omnipaque but existing in experimental groups.Twenty four hours later,the concentrations of the hydroxyproline were determined in different groups and the data were analyzed by statistical software with computer.Results 1.The concentrations of hydroxyproline in the dexamcthasone group,lidocaine group and omnipaque group were significantly lower than that of control group,especially that of lidocaine group,P value was<0.05 or 0.01.2. The concentrations of hydroxyproline in the dexamethasone+lidocaine group,dexamethasone+omnipaque group,lidocaine+omnipaque group and dexamethasone+lidocaine+omnipaque group were significantly lower than that of control group;and simultaneously lower in dexamethasone group,lidocaine group,omnipaque group respectively;P value was also<0.05 or 0.01.Conclusion Dexamethasone,lidocaine and omnipaque can individually inhibit the activity of collagenase at different degrees,so they shouldn't be used together with collagenase in treating the lumber disc herniation.