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Biomed. environ. sci ; Biomed. environ. sci;(12): 373-375, 2017.
Article de Anglais | WPRIM | ID: wpr-311403

RÉSUMÉ

Post-exposure prophylaxis (PEP) has proved to be the most important measure for rabies prevention and control. There is little information regarding adverse reactions to the Essen and 2-1-1 regimens in preschool children (aged 0-6). We reexamined the outcomes of 1,109 preschool children who were vaccinated using SPEEDA under the Essen regimen between January 2011 and December 2012 and 1,267 preschool children under the 2-1-1 regimen between January 2013 and December 2014. We find that, in preschool children, the febrile reaction after the first 2-dose injection in the 2-1-1 regimen was significantly higher than that induced by the first 1-dose in the Essen procedure. Thus, we recommend that the Essen regimen should still be used for rabies PEP in preschool children.


Sujet(s)
Enfant , Enfant d'âge préscolaire , Humains , Nourrisson , Allemagne , Prophylaxie après exposition , Normes de référence , Rage (maladie) , Vaccins antirabiques , Vaccination
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