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Chinese Journal of Virology ; (6): 19-24, 2014.
Artigo em Chinês | WPRIM | ID: wpr-356644

RESUMO

Hepatitis B is one of the most serious global threats to human health. Phylogenetic analysis of hepatitis B virus (HBV) can reveal the evolutionary relationship between HBV sequences and thus provide a basis for the prediction and treatment of hepatitis B and other aspects. In this study, we performed sequence analyses on the HBV sequences of five clinical HBV samples and the HBV sequences retrieved from the GenBank, EMBL, and DDBJ to construct a phylogenetic tree and analyze sequence structures. The experimental results revealed that the C gene of one cloned sequence had a recombinant structure of HBV B/ C subtype. Moreover, the phylogenetic results proved the existence of a newly found subtype HBV/B6 in Xishuangbanna of Yunnan Province, China. The experimental conclusion represents certain value for phylogenetic studies of HBV in Yunnan ethnic minority groups.


Assuntos
Humanos , DNA Recombinante , Genética , Genes Virais , Genética , Técnicas de Genotipagem , Vírus da Hepatite B , Classificação , Genética , Filogenia
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