Successful treatment of cutaneous leishmaniasis with intralesional meglumine antimoniate: A case series
Rev. Soc. Bras. Med. Trop
; Rev. Soc. Bras. Med. Trop;52: e20180211, 2019. tab, graf
Article
in En
| LILACS
| ID: biblio-1003136
Responsible library:
BR1.1
ABSTRACT
Abstract Cutaneous leishmaniasis (CL) is a high-morbidity, vector-borne disease endemic to Colombia. Unlike conventional systemic antileishmanial therapy, intralesional meglumine antimoniate administration has fewer adverse effects and can be as effective and safe. We describe 12 patients treated with intralesional meglumine antimoniate seven with primary and five with recurrent lesions. The majority (11/12) met all cure criteria after 1-7 sessions of meglumine antimoniate administration (1-5 mL). Adverse effects comprised mainly of local pain and edema. Intralesional meglumine antimoniate administration could be an excellent alternative treatment for uncomplicated CL; however, controlled clinical trials are needed to test the efficacy and safety thereof.
Key words
Full text:
1
Index:
LILACS
Main subject:
Leishmaniasis, Cutaneous
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Meglumine Antimoniate
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Antiprotozoal Agents
Limits:
Adult
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Female
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Humans
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Infant
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Male
Language:
En
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
MEDICINA TROPICAL
Year:
2019
Type:
Article