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Analysis of COI and ITS2 regions of DNA obtained from Paragonimus westermani eggs in ancient coprolites on Joseon dynasty mummies
Hong, Jong Ha; Oh, Chang Seok; Seo, Min; Shin, Dong Hoon.
Affiliation
  • Hong, Jong Ha; Seoul National University College of Medicine. Laboratory of Bioanthropology. Paleopathology and History of Diseases. Seoul. KR
  • Oh, Chang Seok; Seoul National University College of Medicine. Laboratory of Bioanthropology. Paleopathology and History of Diseases. Seoul. KR
  • Seo, Min; Dankook University College of Medicine. Department of Parasitology. Cheonan. KR
  • Shin, Dong Hoon; Seoul National University College of Medicine. Laboratory of Bioanthropology. Paleopathology and History of Diseases. Seoul. KR
Mem. Inst. Oswaldo Cruz ; 114: e180595, 2019. tab, graf
Article in En | LILACS | ID: biblio-1040622
Responsible library: BR1.1
ABSTRACT
The genetic information of ancient Paragonimus westermani, the oriental lung fluke infecting over 20 million people worldwide, has not been thoroughly investigated thus far. We analysed genetic markers (COI and ITS2) of P. westermani from coprolite specimens (n = 6) obtained from 15th to 18th century Korean mummies. Our results indicated that all P. westermani sequences were generally distinct from the other species of the genus Paragonimus. The sequences were clustered into three groups Group I for East Asia; Group II for South and Southeast Asia; and Group III for India and Sri Lanka. In this study, we found that ancient P. westermani sequences in Korea belong to Group I, adding invaluable information to the existing knowledge of Paragonimus paleogenetics.
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Full text: 1 Index: LILACS Main subject: Mummies / Electron Transport Complex IV / DNA, Helminth / DNA, Ribosomal Spacer / Paragonimus westermani / Feces Limits: Animals / Humans Country/Region as subject: Asia Language: En Journal: Mem. Inst. Oswaldo Cruz Journal subject: MEDICINA TROPICAL / PARASITOLOGIA Year: 2019 Type: Article

Full text: 1 Index: LILACS Main subject: Mummies / Electron Transport Complex IV / DNA, Helminth / DNA, Ribosomal Spacer / Paragonimus westermani / Feces Limits: Animals / Humans Country/Region as subject: Asia Language: En Journal: Mem. Inst. Oswaldo Cruz Journal subject: MEDICINA TROPICAL / PARASITOLOGIA Year: 2019 Type: Article