In vitro antifungal susceptibility of Candida speciesisolated from diabetic patients
Rev. Soc. Bras. Med. Trop
; 51(4): 542-545, July-Aug. 2018. tab
Article
in En
| LILACS
| ID: biblio-1041473
Responsible library:
BR1.1
ABSTRACT
Abstract INTRODUCTION This study aims to evaluate the antifungal susceptibility of different species of Candida isolated from diabetic patients against eight antifungal agents. METHODS Susceptibility testing of 111 clinical isolates of Candida species was performed against 8 antifungals using the M27-A3 protocol of the Clinical and Laboratory Standards Institute (CLSI). RESULTS Voriconazole, lanoconazole, and caspofungin showed the highest in vitro activity against all the isolates of C. albicans. Resistance against the tested antifungals was only observed in the C. albicans isolates. CONCLUSIONS Our finding revealed that resistance against amphotericin B, itraconazole, ketoconazole, posaconazole, and fluconazole can be observed in C. albicans.
Key words
Full text:
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Index:
LILACS
Main subject:
Candida
/
Diabetes Mellitus
/
Antifungal Agents
Type of study:
Guideline
Limits:
Adult
/
Aged
/
Aged80
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Female
/
Humans
/
Male
Language:
En
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
MEDICINA TROPICAL
Year:
2018
Type:
Article