Nasal Septum Perforation Associated to Histoplasmosis: A Retrospective Study
Pesqui. bras. odontopediatria clín. integr
; 20: e5470, 2020. tab, graf
Article
in En
| BBO, LILACS
| ID: biblio-1135487
Responsible library:
BR1264.1
ABSTRACT
Abstract Objective:
To determine the prevalence of nasal septum perforation associated to Histoplasma sp. Material andMethods:
A retrospective descriptive study was conducted with patients who developed nasal septum perforation associated to histoplasmosis. The diagnosis was made based on clinical manifestations and confirmed with mycological direct examination with Giemsa stain, culture, serologic tests (immunodiffusion method), and histopathology with hematoxylin-eosin, Grocott methenamine (GMS) and Periodic Acid-Schiff stain (PAS).Results:
Out of 1654 medical records reviewed with diagnosis of histoplasmosis in the study period, we found 22 cases with nasal septum perforation. Autoimmune disease was present in 6 patients; all six were on immunosuppressive treatment. Two patients had HIV/AIDS, one of them had also paracoccidiodomycoses and the remaining had no apparent underlying disease or conditions.Conclusion:
Physicians of endemic areas such as Venezuela, must consider this entity in the differential diagnosis with other diseases.Key words
Full text:
1
Index:
LILACS
Main subject:
Acquired Immunodeficiency Syndrome
/
Diagnosis, Differential
/
Nasal Septal Perforation
/
Immunosuppressive Agents
/
Mycoses
Type of study:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
America do sul
/
Venezuela
Language:
En
Journal:
Pesqui. bras. odontopediatria clín. integr
Journal subject:
ODONTOLOGIA
Year:
2020
Type:
Article