Chemical Composition and Antibacterial Effect of Plantago Major Extract on Periodontal Pathogens
Pesqui. bras. odontopediatria clín. integr
; 20: e0012, 2020. tab, graf
Article
in En
| BBO, LILACS
| ID: biblio-1135525
Responsible library:
BR1264.1
ABSTRACT
Abstract Objective:
To determine the in vitro antibacterial effect of different concentrations of the ethanol extract of Plantago major (plantain) on Porphyromonas gingivalis and Fusobacterium nucleatum. Material andMethods:
Bacterial susceptibility tests were used in conjunction with the agar diffusion test and the minimum inhibitory concentration (MIC) test using the broth macrodilution technique.Results:
Different concentrations of ethanol extract (25%, 50%, 75% and 100%) dissolved in 70% ethanol were used, with a positive control (0.12% chlorhexidine + 0.05% cetyl-pyridinium chloride) and a negative control (70% alcohol). The extracts at 75% and 100% showed inhibition halos against both strains studied. With 0.12% chlorhexidine + 0.05% cetyl-pyridinium chloride, inhibition halos averaged 14.9 mm, in contrast to 70º alcohol, where no bacterial inhibition was observed. The MIC was 50% for both species.Conclusion:
The ethanol extract of Plantago major presents an in vitro antibacterial effect on Porphyromonas gingivalis, they may have potential applications in food and pharmaceutical products.Key words
Full text:
1
Index:
LILACS
Main subject:
Plants, Medicinal
/
In Vitro Techniques
/
Plantago major
/
Porphyromonas gingivalis
/
Gram-Negative Bacteria
Country/Region as subject:
America do sul
/
Peru
Language:
En
Journal:
Pesqui. bras. odontopediatria clín. integr
Journal subject:
ODONTOLOGIA
Year:
2020
Type:
Article