Genomic surveillance of the Chikungunya Virus (CHIKV) in Northeast Brazil after the first outbreak in 2014
Rev. Soc. Bras. Med. Trop
; 53: e20190583, 2020. tab, graf
Article
in En
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1136797
Responsible library:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
We performed an epidemiological surveillance of the Chikungunya (CHIKV) lineages in Bahia after the 2014 East/Central/South African (ECSA) genotype outbreak.METHODS:
Reverse-transcription polymerase chain reaction (RT-PCR), viral isolation, and phylogenetic analyses were conducted on serum samples from 605 patients with CHIKV-like symptoms during 2014-2018.RESULTS:
Of the 605 samples, 167 were CHIKV-positive. Viral isolation was achieved for 20 samples; their phylogenetic analysis (E2 protein) revealed the presence of ECSA lineage and reinforced the phylogenetic relationship between ECSA and Indian Ocean lineages.CONCLUSIONS:
The genomic surveillance of CHIKV showed that only ECSA lineage circulated in Bahia since the 2014 outbreak.Key words
Full text:
1
Index:
LILACS
Main subject:
Chikungunya virus
/
Genome, Viral
/
Chikungunya Fever
Type of study:
Screening_studies
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
America do sul
/
Brasil
Language:
En
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
MEDICINA TROPICAL
Year:
2020
Type:
Article