Cost analysis of smear microscopy and the Xpert assay for tuberculosis diagnosis: average turnaround time
Rev. Soc. Bras. Med. Trop
; Rev. Soc. Bras. Med. Trop;53: e20200314, 2020. tab, graf
Article
in En
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1136805
Responsible library:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
Rapid and accurate tuberculosis detection is critical for improving patient diagnosis and decreasing tuberculosis transmission. Molecular assays can significantly increase laboratory costs; therefore, the average time and economic impact should be evaluated before implementing a new technology. The aim of this study was to evaluate the cost and average turnaround time of smear microscopy and Xpert assay at a university hospital.METHODS:
The turnaround time and cost of the laboratory diagnosis of tuberculosis were calculated based on the mean cost and activity based costing (ABC).RESULTS:
The average turnaround time for smear microscopy was 16.6 hours while that for Xpert was 24.1 hours. The Xpert had a mean cost of USD 17.37 with an ABC of USD 10.86, while smear microscopy had a mean cost of USD 13.31 with an ABC of USD 6.01. The sensitivity of smear microscopy was 42.9% and its specificity was 99.1%, while the Xpert assay had a sensitivity of 100% and a specificity of 96.7%.CONCLUSIONS:
The Xpert assay has high accuracy; however, the turnaround time and cost of smear microscopy were lower than those of Xpert.Key words
Full text:
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Index:
LILACS
Main subject:
Tuberculosis, Pulmonary
/
Biological Assay
/
Pathology, Molecular
Type of study:
Diagnostic_studies
/
Health_economic_evaluation
Limits:
Humans
Language:
En
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
MEDICINA TROPICAL
Year:
2020
Type:
Article