Adherence to inhalation therapy and quality of life in children with cystic fibrosis: a cross-sectional study
Clin. biomed. res
; 40(2): 105-110, 2020.
Article
in En
| LILACS
| ID: biblio-1148366
Responsible library:
BR18.1
ABSTRACT
Introduction:
Inhalation therapy is a crucial part of the cystic fibrosis (CF) treatment regimen. Drugs that assist in mucociliary clearance and inhaled antibiotics are used by most patients.Methods:
This is a cross-sectional study where patients with CF and their caregivers answered questionnaires regarding their adherence to inhalation therapy and QoL. Demographic, spirometric, and bacteriological data, as well as S-K scores and hospitalization frequencies were also collected.Results:
We included 66 patients in this study; participants had a mean age of 12.3 years and Z-scores of -1.4 for forced expiratory volume in 1 second and 48.6 for body mass index. Patients were divided into 2 groups according to their self-reported adherence to inhalation therapy high adherence (n = 46) and moderate/low adherence (n = 20). When comparing both groups, there was no statistically significant differences in age, sex, family income, and S-K score (p > 0.05). The high-adherence group had had shorter hospitalization periods in the previous year (p = 0.016) and presented better scores in the following domains of the QoL questionnaire emotion (p = 0.006), eating (p = 0.041), treatment burden (p = 0.001), health perception (p = 0.001), and social (p = 0.046).Conclusions:
A low self-reported adherence to inhalation therapy recommendations was associated with longer hospitalizations in the previous year and with a decrease in QoL in pediatric patients with CF. (AU)Key words
Full text:
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Index:
LILACS
Main subject:
Quality of Life
/
Respiratory Therapy
/
Cystic Fibrosis
/
Treatment Adherence and Compliance
Type of study:
Guideline
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Child
/
Female
/
Humans
/
Male
Language:
En
Journal:
Clin. biomed. res
Journal subject:
MEDICINA
Year:
2020
Type:
Article