SARS-CoV-2 viremia may predict rapid deterioration of COVID-19 patients
Braz. j. infect. dis
;
24(6): 565-569, Nov.-Dec. 2020. tab, graf
Article
in English
| LILACS
| ID: biblio-1153489
ABSTRACT
ABSTRACT COVID-19 has raised worldwide concern as spiraling into a pandemic. Reports about comprehensive investigation of COVID-19 viremia are extremely scanty. Herein, we present four COVID-19 patients with positive SARS-CoV-2 nucleic acid test in blood, accounting for 12.12% of 33 detected cases. Rapid deterioration of these cases with septic shock, accompanying with lung CT images enlarged rapidly, decrease of blood oxygen, heart rate drop (with asynchrony of hypoxemia) accompanied with SARS-CoV-2 viremia. It indicates that massive replication and releasing into blood of SARS-CoV-2 and secondary inflammation storm may lead to injury of multiple organs and poor prognosis. So, positive COVID-19 nucleic acid test in blood may be a good forecasting marker of rapid deterioration of COVID-19 pneumonia. In addition, clearance of viremia may indicate tendency for recovery.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Pneumonia, Viral
/
Coronavirus Infections
/
Betacoronavirus
/
COVID-19
Type of study:
Prognostic study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2020
Type:
Article
Affiliation country:
China
Institution/Affiliation country:
Sun Yat-Sen University/CN
/
Sun Yat-sen University/CN
Similar
MEDLINE
...
LILACS
LIS