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Transcriptome profiling reveals differential expression of genes potentially involved in muscle and adipose tissue development of cattle
Wang, Sihu; Abbas Raza, Sayed Haidar; Mei, Chugang; Zhu, Kai; Garcia, Matthew; Schreurs, Nicola M; Liang, Chengcheng; Yang, Xinran; Zan, Linsen.
  • Wang, Sihu; Northwest A&F University. College of Animal Science and Technology. CN
  • Abbas Raza, Sayed Haidar; Northwest A&F University. College of Animal Science and Technology. CN
  • Mei, Chugang; Northwest A&F University. College of Animal Science and Technology. CN
  • Zhu, Kai; Northwest A&F University. College of Animal Science and Technology. CN
  • Garcia, Matthew; Utah State University. School of Animal Dairy and Veterinary Science. Logan. US
  • Schreurs, Nicola M; Massey University. Animal Science, School of Agriculture and Environment. Palmerston North. NZ
  • Liang, Chengcheng; Northwest A&F University. College of Animal Science and Technology. CN
  • Yang, Xinran; Northwest A&F University. College of Animal Science and Technology. CN
  • Zan, Linsen; Northwest A&F University. College of Animal Science and Technology. CN
Electron. j. biotechnol ; 48: 72-77, nov. 2020. tab, ilus
Article in English | LILACS | ID: biblio-1254810
ABSTRACT

BACKGROUND:

To identify differentially expressed genes (DEGs) between muscle and adipose in cattle, we analyzed the data from the RNA sequencing of three Angus×Qinchuan crossbred cattle.

RESULTS:

Searched the Gene Expression Omnibus (GEO) for a microarray dataset of Yan yellow cattle, GSE49992. After the DEGs were identified, we used STRING and Cytoscape to construct a protein­protein interaction (PPI) network, subsequently analyzing the major modules of key genes. In total, 340 DEGs were discovered, including 21 hub genes, which were mainly enriched in muscle contraction, skeletal muscle contraction, troponin complex, lipid particle, Z disc, tropomyosin binding, and actin filament binding.

CONCLUSIONS:

In summary, these genes can be regarded as candidate biomarkers for the regulation of muscle and adipose development.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Adipose Tissue / Muscle Development / Transcriptome Limits: Animals Language: English Journal: Electron. j. biotechnol Journal subject: Biotechnology Year: 2020 Type: Article Affiliation country: China / New Zealand / United States Institution/Affiliation country: Massey University/NZ / Northwest A&F University/CN / Utah State University/US

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Full text: Available Index: LILACS (Americas) Main subject: Adipose Tissue / Muscle Development / Transcriptome Limits: Animals Language: English Journal: Electron. j. biotechnol Journal subject: Biotechnology Year: 2020 Type: Article Affiliation country: China / New Zealand / United States Institution/Affiliation country: Massey University/NZ / Northwest A&F University/CN / Utah State University/US