Disseminated Intravascular Coagulation Following Induction of Labour with Misoprostol
Niger. j. med. (Online)
; 17(2): 156-158, 2008.
Article
in En
| AIM
| ID: biblio-1267258
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Background:
Disseminated Intravascular coagulopathy (DIC) has been reported following use of Misoprostol which is an old drug with new indications in Obstetrics and Gynecology. Its effectiveness; low cost; stability in tropical conditions and ease of administration as well as side effects like gastrointestinal effect; uterine rupture and post partum haemorrhage (PPH) have been documented.Method:
This is to report a case of disseminated intravascular coagulopathy (DIC) associated with use of misoprostol for induction of labour and to call for extra vigilance in its use.Result:
This was a case of 22-year old gravida 2 para 1 at 42 weeks gestation that was induced with 100?g of isoprostol and delivered a live female baby with good Apgar score. She subsequently developed PPH and epistaxis simultaneously; then conjunctival haemorrhage 30 minutes later. She was managed with fresh whole blood and had a satisfactory recovery.Conclusion:
Life threatening complication could result from use of Misoprostol. More research and high index of suspicion are needed to establish the association of prostaglandins with DIC
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Index:
AIM
Main subject:
Labor, Obstetric
/
Misoprostol
/
Disseminated Intravascular Coagulation
Language:
En
Journal:
Niger. j. med. (Online)
Year:
2008
Type:
Article