Classification of fundus autofluorescence abnormal patterns in diabetic macular edema
Gac. méd. Méx
;
155(5): 458-462, Sep.-Oct. 2019. tab, graf
Article
in English
| LILACS
| ID: biblio-1286543
ABSTRACT
Introduction:
Patients with diabetic macular edema can develop fundus autofluorescence alterations; thus far, these alterations have been more widely studied with scanning or confocal laser systems.Objective:
To describe and classify fundus autofluorescence abnormal patterns in patients with diabetic macular edema using the fundus autofluorescence system with a flash camera.Method:
Observational, retrospective, cross-sectional, descriptive study. Fundus autofluorescence digital images of non-comparative cases with untreated diabetic macular edema, obtained and stored with a flash camera system, were assessed. Inter-observer variability was evaluated.Results:
37 eyes of 20 patients were included. Lens opacity was the most common cause of inadequate image quality. Five different fundus autofluorescence patterns were observed decreased (13%), normal (40%), single-spot hyper-autofluorescent (17 %), multiple-spot hyper-autofluorescent (22 %) and plaque-like hyper-autofluorescent (8 %). The kappa coefficient was 0.906 (p = 0.000).Conclusions:
Different fundus autofluorescence phenotypic patterns are observed with flash camera systems in patients with diabetic macular edema. A more accurate phenotypic classification could help establish prognostic factors for visual loss or for the design of clinical trials for diabetic macular edema.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Macular Edema
/
Diabetic Retinopathy
/
Optical Imaging
Type of study:
Etiology study
/
Observational study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Mexico
Language:
English
Journal:
Gac. méd. Méx
Journal subject:
Medicine
Year:
2019
Type:
Article
Affiliation country:
Mexico
Institution/Affiliation country:
Clínica David/MX
/
Hospital Civil de Guadalajara/MX
/
Hospital Dr. Luis Sánchez Bulnes/MX
/
Secretaría de Salud/MX
/
Universidad Anáhuac Norte/MX
Similar
MEDLINE
...
LILACS
LIS