Dengue fever as a potential cause of sickle cell intrahepatic cholestasis: A report of two cases
Rev. Soc. Bras. Med. Trop
; 54: e00102021, 2021. tab
Article
in En
| LILACS
| ID: biblio-1288093
Responsible library:
BR1.1
ABSTRACT
Abstract Sickle cell intrahepatic cholestasis is a potentially fatal syndrome characterized by jaundice, painful hepatomegaly, and organ dysfunction. Two cases of sickle cell intrahepatic cholestasis associated with dengue fever were described. Endothelial damage/dysfunction is a mechanism involved in severe hepatobiliary complications related to sickle cell diseases. However, the reasons for the lack of increase in the admission of patients with sickle cell disease having severe acute hepatobiliary complications triggered by endothelial damage/dysfunction due to dengue fever remain unknown. This study describes the first association between sickle cell intrahepatic cholestasis and dengue fever.
Key words
Full text:
1
Index:
LILACS
Main subject:
Cholestasis, Intrahepatic
/
Dengue
/
Anemia, Sickle Cell
Language:
En
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
MEDICINA TROPICAL
Year:
2021
Type:
Article