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Bilateral hearing loss as an initial presentation of Creutzfeldt-Jakob disease / Perda auditiva bilateral como uma apresentação inicial da doença de creutzfeldt-jakob
Brito-Marques, Janaina Mariana de Araujo Miranda; Melo, Eduardo Sousa de; Medeiros, Fabíola Lys de; Carvalho, Cristiano Sobral de; Brito-Marques, Paulo Roberto de.
Affiliation
  • Brito-Marques, Janaina Mariana de Araujo Miranda; Department of Neurology, Hospital Universitário Oswaldo Cruz. Universidade de Pernambuco. Recife. BR
  • Melo, Eduardo Sousa de; Department of Neurology, Hospital Universitário Oswaldo Cruz. Universidade de Pernambuco. Recife. BR
  • Medeiros, Fabíola Lys de; Department of Neurology, Hospital Universitário Oswaldo Cruz. Universidade de Pernambuco. Recife. BR
  • Carvalho, Cristiano Sobral de; Department of Neurology, Hospital Universitário Oswaldo Cruz. Universidade de Pernambuco. Recife. BR
  • Brito-Marques, Paulo Roberto de; Department of Neurology, Hospital Universitário Oswaldo Cruz. Universidade de Pernambuco. Recife. BR
Dement. neuropsychol ; 15(4): 548-549, Oct.-Dec. 2021. graf, il
Article in En | LILACS | ID: biblio-1350690
Responsible library: BR15.3
Localization: BR15.3
ABSTRACT
ABSTRACT. We reported a case of a 61-year-old male patient with anacusis, cerebellar syndrome, myoclonus, and frontal signs. The brain magnetic resonance imaging showed bilateral striated hyperintensity of the fluid-attenuated inversion recovery and restricted diffusion in the diffusion-weighted imaging and hypointense areas corresponding to the apparent diffusion coefficient in the cerebral cortex. The autopsy revealed positive immunohistochemistry for the PrPSc protein. Creutzfeldt-Jakob disease presenting with hearing loss is unusual.
RESUMO
RESUMO. Relatamos o caso de um paciente do sexo masculino, 61 anos, com anacusia, síndrome cerebelar, mioclonia e sinais frontais. A ressonância magnética cerebral mostrou hiperintensidade estriada bilateral do fluid-attenuated inversion recovery (FLAIR) e difusão restrita no diffusion-weighted imaging (DWI) e áreas hipointensas correspondendo ao coeficiente de difusão aparente no córtex cerebral. A autópsia revelou imuno-histoquímica positiva para a proteína PrPSc. A doença de Creutzfeldt-Jakob que se apresenta com perda auditiva é incomum.
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Full text: 1 Index: LILACS Main subject: Creutzfeldt-Jakob Syndrome Limits: Humans / Male Language: En Journal: Dement. neuropsychol Journal subject: NEUROCIENCIAS / NEUROLOGIA / PSICOLOGIA / PSIQUIATRIA Year: 2021 Type: Article
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Full text: 1 Index: LILACS Main subject: Creutzfeldt-Jakob Syndrome Limits: Humans / Male Language: En Journal: Dement. neuropsychol Journal subject: NEUROCIENCIAS / NEUROLOGIA / PSICOLOGIA / PSIQUIATRIA Year: 2021 Type: Article