Predictive factors for premature birth and respiratory exacerbation in pregnancies of women with cystic fibrosis
J. pediatr. (Rio J.)
; 98(1): 33-38, Jan.-Feb. 2022. tab
Article
in En
| LILACS
| ID: biblio-1360554
Responsible library:
BR1.1
ABSTRACT
Abstract Objective:
In this present study, the authors evaluated the predictive factors for adverse maternal-fetal outcomes in pregnancies of women with cystic fibrosis (CF). Patients were followed up by a referral center for adults in southern Brazil.Methods:
This is a retrospective cohort study that used data from electronic medical records regarding pregnancies of women diagnosed with CF.Results:
The study included 39 pregnancies related to 20 different women. The main adverse outcomes were high prevalence rates of premature birth (38.5%) and maternal respiratory exacerbation (84.6%). Lower body mass index (BMI) values (< 20.8) and younger ages of CF diagnosis increased the risk of premature birth. The presence of methicillin-resistant and absence of methicillin-sensitive Staphylococcus aureus, as well as a younger age of diagnosis, increased the risk of maternal respiratory exacerbation during pregnancy.Conclusions:
Conception in women with CF is often associated with maternal and fetal complications. Continuous monitoring by a multidisciplinary team should emphasize appropriate nutritional status, investigation of bacterial colonization, and immediate attention to respiratory exacerbations.Key words
Full text:
1
Index:
LILACS
Main subject:
Pregnancy Complications
/
Cystic Fibrosis
/
Premature Birth
Type of study:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
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Female
/
Humans
/
Pregnancy
Language:
En
Journal:
J. pediatr. (Rio J.)
Journal subject:
PEDIATRIA
Year:
2022
Type:
Article