Focal Cortical Dysplasia with hippocampal sclerosis
Autops. Case Rep
;
13: e2023420, 2023. graf
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1420275
ABSTRACT
ABSTRACT Focal Cortical Dysplasia (FCD) is a group of focal developmental malformations of the cerebral cortex cytoarchitecture. FCD usually manifests as medically intractable epilepsy, especially in young children. Live patients are diagnosed by radiological examination such as magnetic resonance imaging (MRI), fluorodeoxyglucose positron emission tomography (FDG PET), magnetoencephalography (MEG), diffusion-tensor imaging (DTI), and intracranial electroencephalogram (EEG). While some cases can be missed by radiological examination, they are usually diagnosed on the histopathological examination of the surgically removed specimens of medically intractable epilepsy patients. We report a case of a young girl with cerebral palsy, mental retardation, and seizure disorder who died in her sleep. The deceased was diagnosed with FCD type III with hippocampal sclerosis on histopathological examination at autopsy. H & E stain and NeuN immunohistochemistry neuronal cell marker were used to demonstrate the findings of FCD.
Full text:
Available
Index:
LILACS (Americas)
Language:
English
Journal:
Autops. Case Rep
Journal subject:
Anatomia
/
Patologia Cl¡nica
/
Patologia Legal
Year:
2023
Type:
Article
Affiliation country:
India
Institution/Affiliation country:
All India Institute of Medical Sciences/IN
/
Vardhman Mahavir Medical College and Safdarjung Hospital/IN
Similar
MEDLINE
...
LILACS
LIS