Facial processing in bipolar disorder is mediated by clinical and biological aspects
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
; 44(6): 602-610, Nov.-Dec. 2022. tab, graf
Article
in En
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LILACS-Express
| LILACS
| ID: biblio-1420522
Responsible library:
BR1.1
ABSTRACT
Objective:
The process of detecting faces can be considered one of the initial steps in face recognition, which is essential for human interaction. We sought to investigate whether a face perception task reliably detects subtle perceptual disturbances between patients with bipolar disorder (BD) and healthy controls.Methods:
In this multisite study, we examined differences between BD patients and matched healthy controls. Participants were instructed to detect the orientation (either left or right) of a face when it was presented as a face/non-face pair on a computer screen using Bayesian entropy estimation. Data analyses compared performance between the groups.Results:
Overall, BD patients exhibited more perceptual disturbances compared with controls. BD patients who took olanzapine had better performance and faster reaction times (RTs) than patients who took lithium or were medication-naive. BD patients who took lithium had better performance and faster RTs than medication-naive patients. The medication-naive BD group exhibited greater disturbances than all other groups.Conclusion:
These findings highlight the reliability of the face perception task used herein and may be important for public health initiatives and follow-up studies that seek to understand the diverse effects of other variables that can affect sensory processing in this population.
Full text:
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Index:
LILACS
Type of study:
Observational_studies
/
Prognostic_studies
Language:
En
Journal:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Journal subject:
PSIQUIATRIA
Year:
2022
Type:
Article
/
Project document