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Correlation between salivary biomarkers and plaque-induced gingivitis exacerbated by pregnancy
Aragon-Martinez, Othoniel; Loredo-Escobar, Karen; Cepeda-Bravo, Juan; Martinez-Morales, Flavio; Gonzalez-Rivera, Maria; Aranda-Romo, Saray.
Affiliation
  • Aragon-Martinez, Othoniel; Autonomous University of San Luis Potosi. School of Medicine. Department of Pharmacology. San Luis Potosi. MX
  • Loredo-Escobar, Karen; Autonomous University of San Luis Potosi. Dentistry School. Periodontics Postgraduate Program. San Luis Potosi. MX
  • Cepeda-Bravo, Juan; Autonomous University of San Luis Potosi. Dentistry School. Periodontics Postgraduate Program. San Luis Potosi. MX
  • Martinez-Morales, Flavio; Autonomous University of San Luis Potosi. School of Medicine. Department of Pharmacology. San Luis Potosi. MX
  • Gonzalez-Rivera, Maria; Autonomous University of San Luis Potosi. School of Medicine. Department of Pharmacology. San Luis Potosi. MX
  • Aranda-Romo, Saray; Autonomous University of San Luis Potosi. Dentistry School. Periodontics Postgraduate Program. San Luis Potosi. MX
J. oral res. (Impresa) ; 11(3): 1-12, jun. 30, 2022. ilus, tab
Article in En | LILACS | ID: biblio-1427927
Responsible library: CL30.1
ABSTRACT
Objetive To evaluate the correlation between salivary biomarkers (the salivary antioxidant ability, salivary level of polyphenols, and other antioxidants) with plaque-induced gingivitis exacerbated by pregnancy in pregnant and nonpregnant women. Material and

Methods:

For this observational study, medical records, dental examinations, and analyses of saliva samples were carried out in pregnant and nonpregnant women. A p-value of <0.05 was considered significant.

Results:

The pregnant women (n =17) exhibited a lower antioxidant capacity (p-value=0.0041), higher levels of polyphenols, gingival index, bleeding on probing, and subjects consuming mineral-enriched products (p-value from <0.0001 to 0.0466), and unchanged levels of phosphotungstic acid reactive substances, proteins, oral hygienic habits, plaque index and probing depth (p-value from 0.0683 to 0.8358), in comparison with the nonpregnant women (n=9). Also, a positive correlation between the gingival index and salivary polyphenol content was observed (r-value = 0.4087, p-value = 0.0202).

Conclusion:

The salivary polyphenols correlate with plaque-induced gingivitis exacerbated by pregnancy, suggesting a deficiency of salivary antioxidant protection.
RESUMEN

Objetivo:

Evaluar la correlación entre los biomarcadores salivales (la capacidad antioxidante salival, el nivel salival de polifenoles y otros antioxidantes) con la gingivitis inducida por placa exacerbada por el embarazo en mujeres embarazadas y no embarazadas. Material y

Métodos:

Para este estudio observacional, se realizaron registros médicos, exámenes dentales y análisis de muestras de saliva en mujeres embarazadas y no embarazadas. Se consideró significativo un valor de p<0,05.

Resultados:

Las gestantes (n=17) presentaron menor capacidad antioxidante (p=0,0041), mayores niveles de polifenoles, índice gingival, sangrado al sondaje y los sujetos que consumían productos enriquecidos con minerales (p<0,0001 a p<0,0466), y no hubo diferencias en los niveles de sustancias reactivas al ácido fosfotúngstico, proteínas, hábitos de higiene bucal, índice de placa y profundidad de sondaje (p=0,0683 a 0,8358), en comparación con las mujeres no embarazadas (n=19). Además, se observó una correlación positiva entre el índice gingival y elcontenido de polifenoles salivales (r = 0,4087, p= 0,0202).

Conclusión:

Los polifenoles salivales se correlacionan con la gingivitis inducida por placa y exacerbada por el embarazo, lo que sugiere una deficiencia de protección antioxidante salival.
Subject(s)
Key words

Full text: 1 Index: LILACS Main subject: Saliva / Biomarkers / Gingivitis Type of study: Observational_studies Limits: Female / Humans / Pregnancy Language: En Journal: J. oral res. (Impresa) Journal subject: ODONTOLOGIA Year: 2022 Type: Article

Full text: 1 Index: LILACS Main subject: Saliva / Biomarkers / Gingivitis Type of study: Observational_studies Limits: Female / Humans / Pregnancy Language: En Journal: J. oral res. (Impresa) Journal subject: ODONTOLOGIA Year: 2022 Type: Article