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Fatores que Afetam a Trombose da Falsa Luz na Dissecção Aórtica Tipo B / Factors Affecting False Lumen Thrombosis In Type B Aortic Dissection
Tang, Qian-hui; Chen, Jing; Yang, Han; Qin, Zhong; Lin, Qiu-ning; Qin, Xiao.
Affiliation
  • Tang, Qian-hui; Guangxi Medical University. The First Affiliated Hospital. Department of Vascular and Endovascular Surgery. Guangxi. CN
  • Chen, Jing; Guangxi Medical University. The First Affiliated Hospital. Department of Vascular and Endovascular Surgery. Guangxi. CN
  • Yang, Han; Guangxi Medical University. The First Affiliated Hospital. Department of Vascular and Endovascular Surgery. Guangxi. CN
  • Qin, Zhong; Guangxi Medical University. The First Affiliated Hospital. Department of Vascular and Endovascular Surgery. Guangxi. CN
  • Lin, Qiu-ning; Guangxi Medical University. The First Affiliated Hospital. Department of Vascular and Endovascular Surgery. Guangxi. CN
  • Qin, Xiao; Guangxi Medical University. The First Affiliated Hospital. Department of Vascular and Endovascular Surgery. Guangxi. CN
Arq. bras. cardiol ; Arq. bras. cardiol;120(8): e20220939, 2023. tab, graf
Article in Pt | LILACS-Express | LILACS | ID: biblio-1447329
Responsible library: BR1.1
RESUMO
Resumo Fundamento A trombose completa da falsa luz facilita a remodelação da dissecção aórtica tipo B (DATB). As características morfológicas afetam a trombose na falsa luz. Objetivos Discutir os fatores pré-admissão presentes, que influenciam a trombose da falsa luz em pacientes com DATB. Metodologia Ao todo, 282 pacientes diagnosticados com DATB em nosso hospital foram estudados, no período entre janeiro de 2008 e dezembro de 2017. Os indivíduos foram divididos em um grupo trombótico e um grupo não trombótico, com base na detecção de qualquer trombo na falsa luz. Analisamos as diferenças entre os dois grupos com relação aos dados clínicos, o comprimento vertical da dissecção e o diâmetro da aorta. Valores de p < 0,05 foram considerados estatisticamente diferentes de modo significativo. Resultados Diferenças significativas entre o grupo trombótico e o grupo não trombótico foram encontradas com relação à idade (53,92 ± 11,40 vs. 50,36 ± 10,71, p = 0,009) e proporção de pacientes com insuficiência renal (7,83% vs. 16,38%, p = 0,026). Nas zonas 3-9, o diâmetro da luz verdadeira do grupo trombótico foi significativamente maior do que no grupo não trombótico (p < 0,05). A análise de regressão logística binária mostrou que o diâmetro da luz verdadeira na zona 5 e a insuficiência renal foram preditores independentes de trombose da falsa luz. Conclusões A idade e a função renal estiveram associadas à trombose na falsa luz. Potencialmente, a diferença entre o diâmetro da luz verdadeira e o da falsa luz pode influenciar na trombose da falsa luz.
ABSTRACT
Abstract Background Complete thrombosis of the false lumen facilitates remodeling of type B aortic dissection (TBAD). Morphological characteristics affect thrombosis in the false lumen. Objectives Discuss the factors present before admission that influence false lumen thrombosis in patients with TBAD. Methods We studied 282 patients diagnosed with TBAD in our hospital between January 2008 and December 2017. We divided the subjects into a thrombotic group and a non-thrombotic group based on whether any thrombus was detectable in the false lumen. We analyzed the differences between the two groups with respect to clinical data, the vertical length of the dissection, and the diameter of the aorta. P values < 0.05 were considered statistically significantly different. Results Significant differences between the thrombotic group and non-thrombotic group were found with respect to age (53.92 ± 11.40 vs. 50.36 ± 10.71, p = 0.009) and proportion of patients with renal insufficiency (7.83% vs. 16.38%, p = 0.026). In zones 3-9, the true lumen diameter of the thrombotic group was significantly larger than in the non-thrombotic group (p < 0.05). Binary logistic regression analysis showed that true lumen diameter in zone 5 and renal insufficiency were independent predictors of false lumen thrombosis. Conclusions Age and renal function were associated with thrombosis in the false lumen. Potentially, the difference between the diameter of the true lumen diameter and that of the false lumen may influence the thrombosis of the false lumen.
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Full text: 1 Index: LILACS Type of study: Prognostic_studies Language: Pt Journal: Arq. bras. cardiol Journal subject: CARDIOLOGIA Year: 2023 Type: Article / Project document

Full text: 1 Index: LILACS Type of study: Prognostic_studies Language: Pt Journal: Arq. bras. cardiol Journal subject: CARDIOLOGIA Year: 2023 Type: Article / Project document