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Comorbidity patterns and mortality among hospitalized patients with psychiatric disorders and COVID-19
Sánchez-Rico, Marina; Rezaei, Katayoun; Delgado-Álvarez, Alfonso; Limosin, Frédéric; Hoertel, Nicolas; Alvarado, Jesús M..
Affiliation
  • Sánchez-Rico, Marina; Assistance Publique-Hôpitaux de Paris, Hôpital Corentin-Celton. Département Médico-Universitaire de Psychiatrie et Addictologie. Issy-les-Moulineaux. FR
  • Rezaei, Katayoun; Assistance Publique-Hôpitaux de Paris, Hôpital Corentin-Celton. Département Médico-Universitaire de Psychiatrie et Addictologie. Issy-les-Moulineaux. FR
  • Delgado-Álvarez, Alfonso; Universidad Complutense de Madrid, Campus de Somosaguas. Facultad de Psicología. Departamento de Psicobiología y Ciencias del Comportamiento. Pozuelo de Alarcon. ES
  • Limosin, Frédéric; Assistance Publique-Hôpitaux de Paris, Hôpital Corentin-Celton. Département Médico-Universitaire de Psychiatrie et Addictologie. Issy-les-Moulineaux. FR
  • Hoertel, Nicolas; Assistance Publique-Hôpitaux de Paris, Hôpital Corentin-Celton. Département Médico-Universitaire de Psychiatrie et Addictologie. Issy-les-Moulineaux. FR
  • Alvarado, Jesús M.; Universidad Complutense de Madrid, Campus de Somosaguas. Facultad de Psicología. Departamento de Psicobiología y Ciencias del Comportamiento. Pozuelo de Alarcon. ES
Braz. J. Psychiatry (São Paulo, 1999, Impr.) ; Braz. J. Psychiatry (São Paulo, 1999, Impr.);45(4): 327-333, Aug. 2023. tab, graf
Article in En | LILACS-Express | LILACS | ID: biblio-1513819
Responsible library: BR1.1
ABSTRACT

Objectives:

To examine the association between psychiatric and non-psychiatric comorbidity and 28-day mortality among patients with psychiatric disorders and COVID-19.

Methods:

Multicenter observational retrospective cohort study of adult patients with psychiatric disorders hospitalized with laboratory-confirmed COVID-19 at 36 Greater Paris university hospitals (January 2020-May 2021) (n=3,768). First, we searched for different subgroups of patients according to their psychiatric and non-psychiatric comorbidities through cluster analysis. Next, we compared 28-day all-cause mortality rates across the identified clusters, while taking into account sex, age, and the number of medical conditions.

Results:

We found five clusters of patients with distinct psychiatric and non-psychiatric comorbidity patterns. Twenty-eight-day mortality in the cluster of patients with mood disorders was significantly lower than in other clusters. There were no significant differences in mortality across other clusters.

Conclusion:

All psychiatric and non-psychiatric conditions may be associated with increased mortality in patients with psychiatric disorders and COVID-19. The lower risk of death among patients with mood disorders might be in line with the potential beneficial effect of certain antidepressants in COVID-19, but requires further research. These findings may help identify at-risk patients with psychiatric disorders who should benefit from vaccine booster prioritization and other prevention measures.
Key words

Full text: 1 Index: LILACS Language: En Journal: Braz. J. Psychiatry (São Paulo, 1999, Impr.) Journal subject: PSIQUIATRIA Year: 2023 Type: Article

Full text: 1 Index: LILACS Language: En Journal: Braz. J. Psychiatry (São Paulo, 1999, Impr.) Journal subject: PSIQUIATRIA Year: 2023 Type: Article