Risk factors and determinants of pulmonary function impairments in chronic respiratory diseases in Ethiopia: A hospital-based cross-sectional study
Ethiop. Med. j
;
62(1): 3-14, 2024.
Article
in English
| AIM
| ID: biblio-1524532
ABSTRACT
Introduction:
Chronic respiratory diseases (CRDs) are diseases of the lung airways and parenchyma. Globally, they are the leading causes of morbidity and mortality. This study aimed to characterize the common CRDs, along with their lung function and possible determinants in symptomatic patients attending Bishoftu General Hospital, Ethiopia.Methods:
A cross-sessional study was conducted at the outpatient of Bishoftu Hospital, Ethiopia from June 2019 to March 2020. Consecutive adult patients aged 18 and above with CRDs (≥8 weeks) were recruited. Questionnaires were used to collect data on demographics, symptoms, diagnoses, and putative risk factors. Lung function was measured by spirometry.Result:
A total of 170 participants were recruited, the majority 102(60.0%) were female. The mean age was 49 years (SD=16). The most common symptoms were wheezing in the last twelve months 156 (91.8%), cough 138 (81.2%), and severe exertional breathlessness 137 (80.6%). Thirty-nine (22.9%) were either active or passive smokers. Half of the patients (50.3%) were exposed daily to vapors, dust, gases, or fumes and 58 (34.3%) were exposed to biomass smoke. In total, 138 (81.2%) had a positive allergen skin prick test. Chronic bronchitis (49.1%) and asthma (36.1%) were the most common clinical diagnoses. Classification of lung function revealed 23 (15%) normal, 29 (19%) obstructive, 36(23.5%) restrictive and 61(39.9%) mixed patterns. Airflow obstruction was independently associated with increasing age (p<0.05), exertional breathlessness (p<0.001), previous history of asthma (p<0.05), BMI (p<0.05), and doctor-diagnosed chronic obstructive pulmonary disease (p<0.001) and asthma (p<0.05).Conclusion:
This study shows a high burden of abnormal lung function in patients attending clinics because of CRDs symptoms. These findings support the critical need for spirometry services to determine lung abnormality in patients with chronic respiratory symptoms.Subject(s)
Fulltext
- https://emjema.org/index.php/EMJ/article/view/2199/947
- https://indexmedicus.afro.who.int/iah/fulltext/Risk factors and determinants of pulmonary function impairments in chronic respiratory diseases in Ethiopia A hospital-based cross-sectional study_Binegdie B.pdf
- https://fi-admin.bvsalud.org/document/view/2hzcj
Full text:
Available
Index:
AIM (Africa)
Type of study:
Etiology study
/
Observational study
/
Prevalence study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Ethiop. Med. j
Year:
2024
Type:
Article
Institution/Affiliation country:
Bishoftu General Hospital, Oromia, Ethiopia/ET
/
Department of Respiratory Medicine, Liverpool School of Tropical Medicine, UK/GB
/
Division of Epidemiology Biostatistics, School of Public Health & Family Medicine, University of Cape Town, South Africa/ZA
/
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, College of Health Sciences, Addis Ababa University, Ethiopia/ET
/
Epidemiological for Public Health, Research and Development/ET
/
Kenya Medical Research Institute (KEMRI), Kenya/KE
/
National Heart and Lung Institute, Imperial College London, UK/GB
/
Spirometry Training Services South Africa/ZA
/
University of California, San Francisco, USA/US
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