Animal models of obesity in rodents. An integrative review
Acta cir. bras
; 31(12): 840-844, Dec. 2016. tab
Article
in En
| LILACS
| ID: biblio-837656
Responsible library:
BR1.1
ABSTRACT
ABSTRACT PURPOSE:
To perform an integrative review of the main animal disease models in rodents used for obesity.METHODS:
Research was conducted in the CAPES Portal database using the following keywords "obesity animal models, diet and rodents", published between the years 2010 to 2016. We found 108 articles, of which 19 were selected and analyzed in full for this study.RESULTS:
Larger part of publications occurred in the last 6 years, the rats (n = 10) were used in the same proportion mice (n = 10). The choice of male animals (n = 18) and age greater than 21 days (n = 17) showed a major highlight. The greater than 5 week follow-up period (n = 18) was the most applied. A High Fat Diet was the most used in studies (n = 18) .CONCLUSIONS:
Male rodents continue to be considered the species most used in experimental studies to induce obesity, also was found variations of age to the beginning of the experiment. For the most part are follow-up time studies along with the use of High Fat Diet.Key words
Full text:
1
Index:
LILACS
Main subject:
Rodentia
/
Animal Experimentation
/
Diet
/
Disease Models, Animal
/
Obesity
Type of study:
Systematic_reviews
Limits:
Animals
Language:
En
Journal:
Acta cir. bras
Journal subject:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2016
Type:
Article