SAMe-TT2 R2 Score: a useful tool in oral anticoagulation decision-making for venous thromboembolism patients? / Escore SAMe-TT2 R2: uma ferramenta útil na tomada de decisão de anticoagulação oral para pacientes com tromboembolismo venoso?
Int. j. cardiovasc. sci. (Impr.)
;
31(5)set.-out. 2018. tab, graf
Article
in English
| LILACS
| ID: biblio-914718
ABSTRACT
Background:
The SAMe-TT2R2 score was introduced to identify atrial fibrillation patients with a high risk of not achieving a good time in therapeutic range (TTR) during vitamin K antagonists (VKA) therapy.Objective:
The aim of this study was to evaluate this score in venous thromboembolism (VTE) patients. Patients andmethods:
A retrospective cohort study of patients receiving care at the outpatient anticoagulation clinic of a tertiary care teaching hospital. Patients were classified as having low (score 0-1) or high risk (score ≥2) of not achieving a good TTR. The area under the ROC curve was calculated to assess the ability of the score to predict a TTR ≥ 65%. Adverse event-free survival curves according to the SAMe-TT2 R2 score were calculated by the Kaplan-Meier method and compared by the log-rank test. A p-value < 0.05 was considered statistically significant.Results:
We investigated 111 patients during a median follow-up of 2.3 (0.7-6.4) years. Mean age was 54.1 ± 15.7 years and 71 (64.0%) were women. Low- and high-risk groups had similar mean TTR (51.9 vs. 49.6%; p = 0.593). The two groups did not differ significantly in the percentage of patients achieving a TTR ≥ 65% (35.6 vs. 25.8%; p =0.370). The c-statistic was 0.595 (p = 0.113) for TTR ≥ 65%. Adverse event-free survival during anticoagulation was also similar in both groups (p = 0.136).Conclusions:
The SAMe-TT2R2 score does not seem to be a useful tool in oral anticoagulation decision-making for patients with VTE and should not be used in thissetting:
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Decision Support Techniques
/
Venous Thromboembolism
/
Anticoagulants
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Int. j. cardiovasc. sci. (Impr.)
Journal subject:
Cardiology
Year:
2018
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Hospital de Clínica de Porto Alegre/BR
/
Hospital de Clínicas de Porto Alegre/BR
/
Hospital de Clínicas e Porto Alegre/BR
Similar
MEDLINE
...
LILACS
LIS