Combination therapy with liposomal amphotericin b (ambisome), n-methylglucamine antimoniate (glucantime), and pentamidine isethionate in a refractory visceral leishmaniasis case
Rev. Soc. Bras. Med. Trop
; Rev. Soc. Bras. Med. Trop;51(3): 393-396, Apr.-June 2018. tab, graf
Article
in En
| LILACS
| ID: biblio-957422
Responsible library:
BR1.1
ABSTRACT
Abstract Visceral leishmaniasis is a systemic disease that is potentially severe and endemic in Brazil. It clinically manifests as fever, weight loss, swelling, hepatosplenomegaly, paleness, and edema. In this study, we discuss a case of a 1-year-old child diagnosed with refractory visceral leishmaniasis after being treated with liposomal amphotericin B in two distinct occasions. Considering the persistent clinical features and weak response to conventional treatment, a combination therapy with liposomal amphotericin B (ambisome), n-methylglucamine antimoniate (glucantime), and pentamidine isethionate was initiated, and response to treatment was good.
Key words
Full text:
1
Index:
LILACS
Main subject:
Organometallic Compounds
/
Pentamidine
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Amphotericin B
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Leishmaniasis, Visceral
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Meglumine
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Antiprotozoal Agents
Limits:
Humans
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Infant
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Male
Language:
En
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
MEDICINA TROPICAL
Year:
2018
Type:
Article