Cardiac magnetic resonance and amyloidosis: review / Ressonância magnética cardíaca e amiloidose: revisão
Int. j. cardiovasc. sci. (Impr.)
;
32(2): 177-189, mar.-abr. 2019. ilus
Article
in English
| LILACS
| ID: biblio-988239
ABSTRACT
Amyloidosis is a disease caused by extracellular deposition of insoluble protein fibrils, that results in changes in tissue architecture and consequently modification of the organ structure. Cardiac involvement is common in amyloidosis. Two major types of systemic amyloidosis affect the myocardium immunoglobulin light chain and transthyretin amyloidosis each leading to different prognosis. Early detection and diagnosis of cardiac amyloidosis are the main objectives in the assessment of the disease. New techniques of magnetic resonance imaging have minimized the need for biopsies for the diagnosis. Late gadolinium enhancement technique, and more recently T1 mapping, have allowed a simplified evaluation of amyloid deposits and extracellular volume. The aim of this review was to describe basic concepts and updates of the use of magnetic resonance imaging for the diagnosis amyloidosis and evaluation of its severity
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Magnetic Resonance Imaging
/
Amyloidosis
Type of study:
Diagnostic study
/
Prognostic study
/
Screening study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Int. j. cardiovasc. sci. (Impr.)
Journal subject:
Cardiology
Year:
2019
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Complexo Hospitalar de Niterói/BR
/
Universidade Federal Fluminense/BR
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