Testicular seminoma: an experience from NCI, Cairo with a protocol for the treatment of stage I seminoma
Journal of the Egyptian National Cancer Institute. 1997; 9 (1): 21-29
in English
| IMEMR
| ID: emr-106394
ABSTRACT
This study was a retrospective analysis of 60 patients with pathologically documented testicular seminoma. The group comprised 21 patients with stage I disease, 17 stage IIa, 17 stage IIb and IIc and five stage III. Cryptorchidism was reported in nine patients and elevated beta subunit of human chorionic gonadotrophin [BHCG] in six. All stage I and IIa patients were treated with radiotherapy alone and reported a five year relapse free actuarial survival rate [RFS] of 93%. Six of stage IIb and IIc patients received radiotherapy and chemotherapy, seven received radiotherapy alone and four received chemotherapy alone. The five-year RFS was 53%. Cryptorchidism did not adversely affect the survival of the patients. High level beta HCG was more commonly encountered in patients with an advanced disease 5/22 in stages IIb, IIc and III compared with 1/38 in stages I and IIa
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Testicular Neoplasms
/
Orchiectomy
/
Seminoma
/
Neoplasm Staging
Type of study:
Practice guideline
Limits:
Humans
/
Male
Language:
English
Journal:
J. Egypt. Natl. Cancer Inst.
Year:
1997
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