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Frequency of hepatitis D virus infection in hepatitis B surface antigen-positive liver diseases
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2011; 21 (1): 23-25
in English | IMEMR | ID: emr-112813
ABSTRACT
To determine the frequency of HDV among hepatitis B surface antigen [HBsAg]-positive liver disorders. An observational cross-sectional study. Medical Unit I, Chandka Medical College Hospital, Larkana, from July 2003 to June 2008. Adult patients with HBs liver related disorders were evaluated for the presence of delta antibodies using commercially available ELISA kits. Descriptive statistcs were used for describing data. Proportions of anti D antibodies between gender and age were compared using chi-square test with significance at p < 0.05. Of the 774 cases, 438 were males [60.4%] and 336 were females [39.6%]. The mean age was 36.5 +/- 14.39 for males and 34.03 +/- 13.16 years for females ranging from 15 to 60 years. Anti-HDV was positive in 183 patients [23.6%].The frequency of HDV was not significantly different between the gender groups [p=0.718]. HDV infection was markedly higher in chronic than acute liver disorders. The HBV/HDV co-infection is frequent in the studied area. Therefore, practitioners and health care managers should be made aware of the risk of dual infection with HBV and HDV
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Index: IMEMR (Eastern Mediterranean) Main subject: Hepatitis Delta Virus / Seroepidemiologic Studies / Cross-Sectional Studies / Hepatitis B Surface Antigens / Liver Diseases Type of study: Prevalence study Limits: Female / Humans / Male Language: English Journal: J. Coll. Physicians Surg. Pak. Year: 2011

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Index: IMEMR (Eastern Mediterranean) Main subject: Hepatitis Delta Virus / Seroepidemiologic Studies / Cross-Sectional Studies / Hepatitis B Surface Antigens / Liver Diseases Type of study: Prevalence study Limits: Female / Humans / Male Language: English Journal: J. Coll. Physicians Surg. Pak. Year: 2011