Enoxaparin plus ticlopidine: an effective combination therapy for intracardiac thrombi in thalassemia intermedia

ABSTRACT

Patients with thalassemia intermedia have an increased risk of thrombotic events as compared to the general population. We describe two cases of thalassemia intermedia with intracardiac thrombi who failed to response to traditional anticoagulation therapy with Unfractionated Heparin and Aspirin; but thrombolysis occurred following combination therapy with Ticlopidine and Enoxaparin. Our experience in patients shown combination of Enoxaparin and Ticlopidine is effective for treatment of ventricular thrombus in TI patients