Are Pneumococci resistant to microlides?
EJMM-Egyptian Journal of Medical Microbiology [The]. 2015; 24 (4): 59-65
in English
| IMEMR
| ID: emr-175723
ABSTRACT
Background:
Streptococcus pneumoniae is the most common cause of acute community - acquired pneumonia and accounts for 30-40% of lower respiratory tract infections. It accounts also for about 50% of hospital-acquired pneumonia. Macrolides remain the primary antibiotic of choice for physicians treating such infections. Macrolide resistance in Strept. pneumoniae is primarily due to two mechanisms; target site modification [encoded by the erm [B] gene] and efflux pump expulsion [encoded by the mef gene]
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Pneumococcal Infections
/
Streptococcus pneumoniae
/
Tetracycline
/
Drug Resistance, Microbial
/
Clindamycin
/
Macrolides
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
English
Journal:
Egypt. J. Med. Microbiol.
Year:
2015
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