[ influence of cerebrospinal fluid accompanied by retinoic acid on differentiation of bone marrow mesenchymal stem cells into neuron-like cells in vitro]
Modares Journal of Medical Sciences, Pathobiology. 2016; 18 (4): 79-91
in Persian
| IMEMR
| ID: emr-185187
ABSTRACT
Objective:
Cerebrospinal fluid [CSF] has a broad range of molecules and neurotrophic factors essential for neurogenesis. Bone marrow mesenchymal stem cells [BMSCs] are multipotent stem cells that can differentiate into the cells with neural-like phenotype under the induction of appropriate growth factors. According to the significant role of retinoic acid [RA] in neurogenesis, this study aims to differentiate BMSCs into neuronlike cells using CSF, RA, and the combination of CSF and RA
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Index:
IMEMR (Eastern Mediterranean)
Language:
Persian
Journal:
Modares J. Med. Sci., Pathobiol.
Year:
2016
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