Cell Journal [Yakhteh]. 2017; 18 (4): 532-539
in English
| IMEMR
| ID: emr-185778
ABSTRACT
Objective:
CRISPR/Cas9 technology provides a powerful tool for targeted modification of genomes. In this system, a donor DNA harboring two flanking homology arms is mostly used for targeted insertion of long exogenous DNA. Here, we introduced an alternative design for the donor DNA by incorporation of a single short homology arm into a circular plasmid
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Genetic Engineering
/
Gene Targeting
/
Embryonic Stem Cells
/
Gene Knock-In Techniques
/
Homologous Recombination
/
Mice
Language:
English
Journal:
Cell J. [Yakhteh]
Year:
2017
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