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Hydrocortisone promotes differentiation of mouse embryonic stem cell-derived definitive endoderm toward Lunga alveolar epithelial cells
Cell Journal [Yakhteh]. 2019; 20 (4): 469-476
in English | IMEMR (Eastern Mediterranean) | ID: emr-199615
Responsible library: EMRO
ABSTRACT

OBJECTIVE:

The ability to generate lung alveolar epithelial type II [ATII] cells from pluripotent stem cells [PSCs] enables the study of lung development, regenerative medicine, and modeling of lung diseases. The establishment of defined, scalable differentiation methods is a step toward this goal. This study intends to investigate the competency of small molecule induced mouse embryonic stem cell-derived definitive endoderm [mESC-DE] cells towards ATII cells

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Index: IMEMR (Eastern Mediterranean) Language: English Journal: Cell J. [Yakhteh] Year: 2019