Nebulette expression is associated with lymph node metastasis in patients with colorectal cancer

ABSTRACT

Background:Colorectal cancer [CRC] is one of the most common cancers among men and women worldwide. Cancer metastasis is the main cause of death in patients with cancer. NEBL [nebulette, Gene ID 10529] protein interacts with thin filaments in the cell and may functionally destabilize focal adhesion composition. There are some studies on NEBL gene expression alteration in cancer. In the presented study we aimed to analyze NEBL gene expression in patients with colorectal cancer to explore possible association of this gene with clinicopathological features in CRC