Evaluation of insulin-like growth factor binding protein-1 in cervico-vaginal secretions as an indicator of premature rupture of membranes: a comparison with nitrazine test and amniotic fluid index

ABSTRACT

Objective: To evaluate the diagnostic potential of insulin-like growth factor binding protein-1 [IGFBP-1] in cervicovaginal secretions as an indicator of premature rupture of membranes [PROM] in comparison with the nitrazine test and amniotic fluid index [AFI]. The predictivity of these tests on the latency of pregnancy in patients with PROM was also studied