Design and development of modified mRNA encoding core antigen of hepatitis C virus: a possible application in vaccine production
IBJ-Iranian Biomedical Journal. 2019; 23 (1): 57-67
in English
| IMEMR
| ID: emr-202862
ABSTRACT
Introduction:
Hepatitis C virus [HCV] is a ?blood-borne pathogen, resulting in liver cirrhosis and liver cancer. Despite of many efforts in development of treatments for HCV, no vaccine has been licensed yet. The purpose of this study was ?to design and prepare a specific mRNA, without 5' cap and poly [A] tail transcribed in vitro capable of coding core protein and also to determine its functionality
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Index:
IMEMR (Eastern Mediterranean)
Language:
English
Journal:
Iran. Biomed. J.
Year:
2019
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