Effect of Sambucus ebulus extract on neural stem cell prolifration under oxidative stress condition

ABSTRACT

Background and Aim: Recently, several studies have indicated that the central nervous system has the capacity for endogenous repair. But, the proliferation capacity of endogenous neural stem cells [NSCs] isn't sufficient for the treatment of neurodegenerative diseases. So, it sounds that stimulation of endogenous NSC proliferation is essential for neuroregeneration. The aim of this study was to examine the effects of Sambucus ebulus extract on the proliferation of neonatal rat hippocampus-derived neural stem cells [NSCs] under oxidative stress condition induced by H2O2