Your browser doesn't support javascript.
loading
How aluminum is taken up by red blood cells: a study in relation to hypochromic microcytic anemia in hemodialyzed patients
Medical Journal of the Islamic Republic of Iran. 1993; 7 (2): 87-93
in En | IMEMR | ID: emr-29323
Responsible library: EMRO
Investigation of aluminium uptake by human erythrocytes was the major aim of this study. Packed red blood cells were incubated in Earle's medium [pH 7.4] containing varying concentrations of aluminium [0-160 micro g/l] as A1K[SO[4]][2] and aluminium content of the cells were determined using flameless atomic absorption. There was significant increase in aluminium content of the cells. Addition of 5 mM glucose caused an elevation of red cell aluminium, whereas depletion of red cells from ATP caused a marked reduction in aluminium uptake. Both ouabain and vanadate, when added to the medium, caused a significant reduction in aluminium uptake in line with a decrease in ATP ase activity
Subject(s)
Search on Google
Index: IMEMR Main subject: Aluminum / Anemia, Hypochromic / Kidney Failure, Chronic Language: En Journal: Med. J. Islamic Rep. Iran Year: 1993
Search on Google
Index: IMEMR Main subject: Aluminum / Anemia, Hypochromic / Kidney Failure, Chronic Language: En Journal: Med. J. Islamic Rep. Iran Year: 1993