Effect of diazinon and / or praziquantel on selected protein aspects in healthy and Schistosoma mansoni infected mice
Journal of the Egyptian Society of Parasitology. 2003; 33 (1): 145-62
in English
| IMEMR
| ID: emr-62832
ABSTRACT
The effect of 1/20 LD50 diazinon given orally to healthy and Schistosomiasis mansoni infected mice for 5-9 successive days and 17 weeks coupled with a therapeutic dose [2x500 mg/kg b. Wt.] of praziquantel two weeks before sacrificing. The results showed insignificant differences obtained from total proteins, albumin, globulins and albumin/globulin ratio. However, significant differences were revealed from alpha 1, alpha 2, beta 1, beta 2 and gamma-globulins in addition to plasma ceruloplasmin. Diazinon changed the levels of alpha 2, beta 1 and gamma-globulins, while diazinon coupled with schistosomiasis affected the levels of most of the studies parameters
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Praziquantel
/
Schistosoma mansoni
/
Ceruloplasmin
/
Proteins
/
Cholinesterase Reactivators
/
Diazinon
/
Albumins
/
Drug Combinations
/
Mice
Limits:
Animals
Language:
English
Journal:
J. Egypt. Soc. Parasitol.
Year:
2003
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