Egyptian Journal of Nutrition and Health. 2008; 3 (1): 25-40
in En
| IMEMR
| ID: emr-86259
Responsible library:
EMRO
ABSTRACT
The objective of this study was to evaluate the efficacy of the consumption of bioactive yogurt [probiotic] in combination with Nabq fruit [Zizyphus Spina Christi, ZSC] extract as bioavailable isoflavone in osteoporotic postmenopausal women..Analysis by HPLC of ZSC extract showed that the main constituents of this extract exhibited a chromatographic profile corresponding to rutin, quercereterin, quercin, kamaferol, chlorogenic and ferrulic. The study was conducted on 25 postmenopausal women.Our results revealed that the level of serum osteocalcin [OC] was significantly decreased on daily consumption of yogurt fortified with Bifidobacteria in combination with ZSC extract. This indicated down-regulation of bone turn-over. The level of serum parathyroid hormone [PTH] and ionized calcium [Ca2+] were also reduced significantly. This study proposed that phytoestrogens efficacy of ZSC extract in combination with probiotics prevent bone mineral loss due to ovarian estrogen deficiency possibly by promoting intestinal calcium absorption and enhancing antiresorptive agent in osteoporotic postmenopausal women
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Index:
IMEMR
Main subject:
Parathyroid Hormone
/
Whales
/
Women
/
Bifidobacterium
/
Plant Extracts
/
Osteocalcin
/
Calcium
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Chromatography, High Pressure Liquid
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Isoflavones
Limits:
Female
/
Humans
Language:
En
Journal:
Egypt. J. Nutr. Health
Year:
2008