Glanzmann's thrombasthenia and pregnancy

ABSTRACT

Glanzmann's thrombasthenia is rare autosomal recessive platelet disorder caused by abnormal platelet glycoprotein complex [GP IIb-IIIa] leading to excessive mucosal bleeding. Patients with Glanzmann's thrombasthenia may present with hemorrhagic symptoms including mucosal bleeding, easy bruising and post-surgical bleeding. We report a 37-year old lady, who underwent a cesarean section at term. She received recombinant factor VIIa at the time of surgery. She had uneventful post operative period and she was discharged home in good general conditions