Common HBV genotype in southeastern Iranian patients
Archives of Iranian Medicine. 2010; 13 (2): 147-149
in En
| IMEMR
| ID: emr-98457
Responsible library:
EMRO
ABSTRACT
Asymptomatic hepatitis B infection is characterized as a type of hepatitis in which hepatitis B surface antigen is present in the patient's peripheral blood despite the absence of clinical symptoms. Previous studies have shown that a particular genotype may effect clinical manifestations of hepatitis B infection; hence, the aim of the current study was to determine the frequency of hepatitis B virus genotypes among asymptomatic carriers of hepatitis B. In this experimental study, the plasma samples of 100 asymptomatic carriers were collected and tested for HBsAg and anti-HBs using ELISA. The genotype of hepatitis B virus was determined by the GAP-PCR technique. The results of this study showed that all samples were positive for hepatitis B surface antigen and anti-hepatitis B core antigen was present in 60 [60%] cases. Our results also indicated that all patients had the D genotype of hepatitis B virus
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Index:
IMEMR
Main subject:
Polymorphism, Genetic
/
Enzyme-Linked Immunosorbent Assay
/
Polymerase Chain Reaction
/
Genotype
/
Hepatitis B Surface Antigens
Limits:
Humans
Language:
En
Journal:
Arch. Iran. Med.
Year:
2010