Disturbances in the serum progesterone levels during the luteal phase

The major cause of female infertility is the disturbance of the hormones of hypothalamic-pituitary-gonadal axis and progesterone is a major component of this axis. The present study was carried out to determine the incidence of luteal phase defect of progesterone in a group of 150 regularly menstruating female subjects. Luteal phase defect to progesterone was seen in 43.3% patients, 40% having fairly low level of progesterone and 3.3% exhibiting higher levels